Pilocarpine nitrate

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Pilocarpine nitrate

Product Name: Pilocarpine nitrate
CAS No.: 148-72-1
Chemical Name: Pilocarpine nitrate
Synonyms: Nitrat;Pilocarpine nitrate for system suitability CRS;Pilagan;pilofrin;Pilocarpinnitrat;Einecs 205-723-7;Pilocarpin Nitrate;Pilocarpini nitras;PILOCARPINE NITRATE;p.v.carpineliquifilm
CBNumber: CB4237796
Molecular Formula: C11H17N3O5
Formula Weight: 271.27
MOL File: 148-72-1.mol

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Pilocarpine nitrate Property

Melting point:: 173,5-174°C
alpha: D +77 to +83° (c = 10)
refractive index: 81 ° (C=2, H2O)
storage temp.: 2-8°C
solubility: H₂O: 0.1 g/mL, clear, very faintly yellow
form: powder
color: white
optical activity: [α]25/D +83°, c = 10 in H2O(lit.)
Merck: 14,7424
BRN: 4171406
CAS DataBase Reference: 148-72-1(CAS DataBase Reference)
EPA Substance Registry System: Pilocarpine nitrate (148-72-1)

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Safety

Hazard Codes: Xn,T+
Risk Statements: 22-26/28
Safety Statements: 1-25-45
RIDADR: 3087
WGK Germany: 3
RTECS: TK1455000
F: 3-10
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 2939800000
Toxicity: LD50 oral in rat: 911mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H272May intensify fire; oxidizer

H302Harmful if swallowed

H330Fatal if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P220Keep/Store away from clothing/…/combustible materials.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P0597
Product name: Pilocarpine nitrate
Purity: meets USP testing specifications
Packaging: 5g
Price: $439
Updated: 2024/03/01

Sigma-Aldrich

Product number: P0597
Product name: Pilocarpine nitrate
Purity: meets USP testing specifications
Packaging: 25g
Price: $918
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP503
Product name: Pilocarpine nitrate
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 200MG
Price: $223
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0000106
Product name: Pilocarpine nitrate for system suitability
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000106
Price: $153
Updated: 2024/03/01

Sigma-Aldrich

Product number: P6628
Product name: Pilocarpine nitrate salt
Purity: ≥98% (HPLC)
Packaging: 10g
Price: $244
Updated: 2024/03/01

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Pilocarpine nitrate Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, sensitive to light.

Uses

antiglaucoma agent, miotic

Uses

Antiglaucoma drug;Cholinergic

Uses

Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.

brand name

Pilagan (Allergan).

General Description

Pilocarpine mononitrate occursas shining white crystals that are not hygroscopic butare light sensitive. It is soluble in water (1:4) and alcohol(1:75) but insoluble in chloroform and ether. Aqueoussolutions are slightly acid to litmus and may be sterilizedin the autoclave. The alkaloid is incompatible with alkalies,iodides, silver nitrate, and reagents that precipitatealkaloids.

Biochem/physiol Actions

Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.

Pilocarpine nitrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pilocarpine nitrate manufacturers

Henan Fengda Chemical Co., Ltd

Product: Pilocarpine nitrate 148-72-1
Price: US $35.00-1.30/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

Dideu Industries Group Limited

Product: Pilocarpine nitrate 148-72-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-27

148-72-1, Pilocarpine nitrateRelated Search:

(+)-Pilocarpine hydrochloride Tribenuron methyl Thiophanate-methyl Thiamine nitrate Econazole nitrate NITRATE N-Ethylmethylamine Methyl acetate SECURININE METSULFURON METHYL PILOCARPINE 13,14-Didehydromatridin-15-one Imidazole Kresoxim-methyl Miconazole Nitrate Methyl salicylate Methyl Potassium nitrate

3-ETHYLDIHYDRO-4-[(1-METHYL-1H-IMIDAZOL-5-YL)-METHYL]-2-(3H)-FURANONE NITRATE

2(3H)-Furanone, 3-ethyldihydro-4-(1-methyl-1H-imidazol-5-yl)methyl-, (3S,4R)-, mononitrate

PILOCARPINENITRATE,CRYSTAL,USP

Pilagan

Pilocarpinnitrat

(3S)-3-Ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one nitrate

(3S,4R)-3-Ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone mononitrate

Pilocarpini nitras

(3S,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate

2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S,4R)-, nitrate (1:1)

2(3H)-Furanone, 3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-, (3S-cis)-, mononitrate

Einecs 205-723-7

Pilocarpine Nitrate (200 mg)

Pilocarpin Nitrate

PILOCARPINE NITRATE, PH EUR

Nitrat

Pilocarpine Nitrate Impurity Ⅰ:(3R,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate

PILOCARPINE NITRATE

PILOCARPINE NITRATE SALT

3-ethyldihydro-4-[(1-methyl-1h-imidazol-5-yl)methyl]-2(3h)-furanon(3s-cis)

p.v.carpineliquifilm

pilocarpine,mononitrate

Pilocarpinenitrateusp

pilocarpinesubnitrate

pilofrin

Pilocarpine nitrate for system suitability CRS

Pilocarpine nitrate CRS

Pilocarpine nitrate USP/EP/BP

Pilocarpine NitrateQ: What is Pilocarpine Nitrate Q: What is the CAS Number of Pilocarpine Nitrate Q: What is the storage condition of Pilocarpine Nitrate Q: What are the applications of Pilocarpine Nitrate

Pilocarpine Nitrate Impurity Ⅰ:(3R,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate

Pilocarpine Nitrate (1539009)

Pilocarpinenitratesal

Pilocarpine,Inhibitor,inhibit,mAChR,Muscarinic acetylcholine receptor,Pilocarpine nitrate

(2R,3R)-2-ethyl-3-(hydroxymethyl)-4-(1-methyl-1H-imidazol-5-yl)butanoic acid (isopilocarpic acid)

Ametryn Impurity 21(Simetryne)

148-72-1

C11H16N2O2HNO3

Alkaloids (Others)

Alkaloids

Inhibitors

AgonistsDrugs of Abuse

Chemical Structure

Cholinergics

Neurotransmitters

Others

Alkaloids

Alkaloids (Others)

Biochemistry

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