ChemicalBook > CAS DataBase List > N-Hydroxyethylphthalimide

N-Hydroxyethylphthalimide

Product Name
N-Hydroxyethylphthalimide
CAS No.
3891-07-4
Chemical Name
N-Hydroxyethylphthalimide
Synonyms
N-(2-HYDROXYETHYL)PHTHALIMIDE;AKOS BBS-00004429;TIMTEC-BB SBB003638;2-PHTHALIMIDOETHANOL;N-Hydroxyethylphthal;Amlodipine Impurity Q;Alogliptin impurity Q;N-hydroethyl phthalimide;N-HYDROXYETHYLPHTHALIMIDE;2-Hydroxyethylphthalimide
CBNumber
CB4241489
Molecular Formula
C10H9NO3
Formula Weight
191.18
MOL File
3891-07-4.mol
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N-Hydroxyethylphthalimide Property

Melting point:
126-128 °C(lit.)
Boiling point:
326.92°C (rough estimate)
Density 
1.2722 (rough estimate)
refractive index 
1.5310 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
14.40±0.10(Predicted)
color 
White
BRN 
147214
InChIKey
MWFLUYFYHANMCM-UHFFFAOYSA-N
CAS DataBase Reference
3891-07-4(CAS DataBase Reference)
NIST Chemistry Reference
N-2-hydroxyethyl phthalimide(3891-07-4)
EPA Substance Registry System
1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)- (3891-07-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36/37/39-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29251900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
138339
Product name
N-(2-Hydroxyethyl)phthalimide
Purity
99%
Packaging
100g
Price
$106
Updated
2024/03/01
TCI Chemical
Product number
H0245
Product name
N-(2-Hydroxyethyl)phthalimide
Purity
>98.0%(HPLC)(N)
Packaging
25g
Price
$43
Updated
2024/03/01
TCI Chemical
Product number
H0245
Product name
N-(2-Hydroxyethyl)phthalimide
Purity
>98.0%(HPLC)(N)
Packaging
500g
Price
$352
Updated
2024/03/01
Alfa Aesar
Product number
A14259
Product name
N-(2-Hydroxyethyl)phthalimide, 98+%
Packaging
100g
Price
$53.65
Updated
2024/03/01
Alfa Aesar
Product number
A14259
Product name
N-(2-Hydroxyethyl)phthalimide, 98+%
Packaging
500g
Price
$178.65
Updated
2024/03/01
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N-Hydroxyethylphthalimide Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

N-(2-Hydroxyethyl)phthalimide is used as a reagent to synthesize (-)-R-rolipram is a phosphodiesterase 4 inhibitor that is used to treat depression. N-(2-Hydroxyethyl)phthalimide is also used as a reagent to synthesize FR252921, a compound that acts as an immunosuppressant. Amlodipine Impurity 6

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 4, p. 106, 1963
The Journal of Organic Chemistry, 24, p. 1122, 1959 DOI: 10.1021/jo01090a601

General Description

N-(2-Hydroxyethyl)phthalimide is the precursor for chloromethyl ethers used in the synthesis of purine acyclic nucleosides.

N-Hydroxyethylphthalimide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Hydroxyethylphthalimide Suppliers

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View Lastest Price from N-Hydroxyethylphthalimide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
N-Hydroxyethylphthalimide 3891-07-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Weibang Biotechnology Co., Ltd
Product
N-Hydroxyethylphthalimide 3891-07-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01
Hebei Chuanghai Biotechnology Co,.LTD
Product
N-Hydroxyethylphthalimide 3891-07-4
Price
US $30.00-10.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100000kg
Release date
2024-08-22

3891-07-4, N-HydroxyethylphthalimideRelated Search:

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  • AKOS BBS-00004429
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  • 2-(2-hydroxyethyl)-1h-isoindole-3(2h)-dione
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  • Phthalimide, N-(2-hydroxyethyl)-
  • N- hydroxyethyl ortho - two - methimide
  • AMlodipine Related IMpurity 6 (N-(2-Hydroxyethyl)phthaliMide)
  • N-(2-Hydroxyethyl)phthaliMide, >=97.0%
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  • N-(2-Hydroxyethyl)phthalimide, 98+%
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  • N-(2-Hydroxyethyl)phthaliMide, 99% 25GR
  • Amlodipine Impurity Q
  • N-(2-Hydroxyethyl)phthalimide&gt
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  • N-(2-HYDROXYETHYL) PHTHALIMIDE For synthesis
  • N-Hydroxyethylphthalimide End use: Phthaloyl Amlodipine
  • 3891-07-4
  • 891-07-4
  • 389-07-4
  • 3891-7-4
  • 727-38-4
  • Organic Building Blocks
  • Cyclic Imides
  • N-Substituted Maleimides, Succinimides & Phthalimides
  • N-Substituted Phthalimides
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  • ALCOHOL
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