ChemicalBook > CAS DataBase List > 8-Bromo-6-chloroimidazo[1,2-a]pyridine

8-Bromo-6-chloroimidazo[1,2-a]pyridine

Product Name: 8-Bromo-6-chloroimidazo[1,2-a]pyridine
CAS No.: 957187-27-8
Chemical Name: 8-Bromo-6-chloroimidazo[1,2-a]pyridine
Synonyms: 8-Bromo-6-chloroimidazo[1,2-a]pyridine;6-chloro-8-bromoimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridine, 8-broMo-6-chloro-
CBNumber: CB42470964
Molecular Formula: C7H4BrClN2
Formula Weight: 231.48
MOL File: 957187-27-8.mol

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8-Bromo-6-chloroimidazo[1,2-a]pyridine Property

Melting point:: 125-128℃
Density: 1.84±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.23±0.50(Predicted)
Appearance: White to off-white Solid
Water Solubility: Slightly soluble in water.

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: B678143
Product name: 8-Bromo-6-chloroimidazo[1,2-a]pyridine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB152982
Product name: 8-Bromo-6-chloro-imidazo[1,2-a]pyridine
Packaging: 2mg
Price: $59
Updated: 2021/12/16

ChemScene

Product number: CS-0041819
Product name: 8-Bromo-6-chloroimidazo[1,2-a]pyridine
Purity: 99.61%
Packaging: 5g
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-0041819
Product name: 8-Bromo-6-chloroimidazo[1,2-a]pyridine
Purity: 99.61%
Packaging: 1g
Price: $22
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB152982
Product name: 8-Bromo-6-chloro-imidazo[1,2-a]pyridine
Packaging: 5mg
Price: $117
Updated: 2021/12/16

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8-Bromo-6-chloroimidazo[1,2-a]pyridine Chemical Properties,Usage,Production

Uses

8-Bromo-6-chloroimidazo[1,2-a]pyridine is used as an organic chemical synthesis intermediate.

Synthesis

107-20-0

26163-03-1

957187-27-8

3-Bromo-5-chloropyridin-2-amine (10 g, 49 mmol) and chloroacetaldehyde (50% aqueous, 12 mL, 98 mmol) were mixed in ethanol (100 mL) and the reaction was heated at 50 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated. To the concentrated residue was added acetone (30 mL) and stirred rapidly for 2 hours. The resulting solid was collected by filtration and dried to afford the target product 8-bromo-6-chloroimidazo[1,2-a]pyridine (10.0 g, 89% yield). Mass spectrometry analysis showed [M + H]+ peak of 231. 1H NMR (500 MHz, DMSO) data were as follows: δ 9.20 (s, 1H), 8.33 (s, 1H), 8.29 (s, 1H), 8.09 (s, 1H).

References

[1] Patent: US2013/116262, 2013, A1. Location in patent: Paragraph 0195; 0196; 0197
[2] Patent: WO2011/72064, 2011, A1. Location in patent: Page/Page column 74

8-Bromo-6-chloroimidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 8-Bromo-6-chloroimidazo[1,2-a]pyridine manufacturers

Career Henan Chemical Co

Product: 8-Bromo-6-chloroimidazo[1,2-a]pyridine 957187-27-8
Price: US $0.10/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 1kg,10kg,100kg
Release date: 2020-01-09

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