ChemicalBook > CAS DataBase List > 8-Bromo-6-chloroimidazo[1,2-a]pyridine

8-Bromo-6-chloroimidazo[1,2-a]pyridine

Product Name
8-Bromo-6-chloroimidazo[1,2-a]pyridine
CAS No.
957187-27-8
Chemical Name
8-Bromo-6-chloroimidazo[1,2-a]pyridine
Synonyms
8-Bromo-6-chloroimidazo[1,2-a]pyridine;6-chloro-8-bromoimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridine, 8-broMo-6-chloro-
CBNumber
CB42470964
Molecular Formula
C7H4BrClN2
Formula Weight
231.48
MOL File
957187-27-8.mol
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8-Bromo-6-chloroimidazo[1,2-a]pyridine Property

Melting point:
125-128℃
Density 
1.84±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.23±0.50(Predicted)
Appearance
White to off-white Solid
Water Solubility 
Slightly soluble in water.
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
B678143
Product name
8-Bromo-6-chloroimidazo[1,2-a]pyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB152982
Product name
8-Bromo-6-chloro-imidazo[1,2-a]pyridine
Packaging
2mg
Price
$59
Updated
2021/12/16
ChemScene
Product number
CS-0041819
Product name
8-Bromo-6-chloroimidazo[1,2-a]pyridine
Purity
99.61%
Packaging
5g
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-0041819
Product name
8-Bromo-6-chloroimidazo[1,2-a]pyridine
Purity
99.61%
Packaging
1g
Price
$22
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB152982
Product name
8-Bromo-6-chloro-imidazo[1,2-a]pyridine
Packaging
5mg
Price
$117
Updated
2021/12/16
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8-Bromo-6-chloroimidazo[1,2-a]pyridine Chemical Properties,Usage,Production

Uses

8-Bromo-6-chloroimidazo[1,2-a]pyridine is used as an organic chemical synthesis intermediate.

Synthesis

107-20-0

26163-03-1

957187-27-8

3-Bromo-5-chloropyridin-2-amine (10 g, 49 mmol) and chloroacetaldehyde (50% aqueous, 12 mL, 98 mmol) were mixed in ethanol (100 mL) and the reaction was heated at 50 °C overnight. Upon completion of the reaction, the mixture was cooled to room temperature and concentrated. To the concentrated residue was added acetone (30 mL) and stirred rapidly for 2 hours. The resulting solid was collected by filtration and dried to afford the target product 8-bromo-6-chloroimidazo[1,2-a]pyridine (10.0 g, 89% yield). Mass spectrometry analysis showed [M + H]+ peak of 231. 1H NMR (500 MHz, DMSO) data were as follows: δ 9.20 (s, 1H), 8.33 (s, 1H), 8.29 (s, 1H), 8.09 (s, 1H).

References

[1] Patent: US2013/116262, 2013, A1. Location in patent: Paragraph 0195; 0196; 0197
[2] Patent: WO2011/72064, 2011, A1. Location in patent: Page/Page column 74

8-Bromo-6-chloroimidazo[1,2-a]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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8-Bromo-6-chloroimidazo[1,2-a]pyridine Suppliers

China 70 India 1 United Kingdom 3 United States 7 Global 81
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 8-Bromo-6-chloroimidazo[1,2-a]pyridine manufacturers

Career Henan Chemical Co
Product
8-Bromo-6-chloroimidazo[1,2-a]pyridine 957187-27-8
Price
US $0.10/g
Min. Order
1g
Purity
98%min
Supply Ability
1kg,10kg,100kg
Release date
2020-01-09

957187-27-8, 8-Bromo-6-chloroimidazo[1,2-a]pyridineRelated Search:

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