Z-Vad-fmk, non-methylated

Product Name: Z-Vad-fmk, non-methylated
CAS No.: 161401-82-7
Chemical Name: Z-Vad-fmk, non-methylated
Synonyms: Z-VAD;abs817872;Z-VAD-FMK, Free Acid;Z-VAD-FMK (Caspase Inhibitor VI);Z-VAD(OH)-FMK (Caspase Inhibitor VI);Z-VAL-ALA-ASP-(OH)-FLUOROMETHYL KETONE;Carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone;Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem;inhibit,Inhibitor,ZVADFMK,Hela,Z VAD FMK,Caspase,Antiapoptosis,cells,pan-caspase;L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-
CBNumber: CB42497499
Molecular Formula: C21H28FN3O7
Formula Weight: 453.46
MOL File: 161401-82-7.mol

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Z-Vad-fmk, non-methylated Property

Boiling point:: 758.0±60.0 °C(Predicted)
Density: 1.260±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO:5.0(Max Conc. mg/mL);11.0(Max Conc. mM)
form: Off-white solid
pka: 3.91±0.19(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 219007
Product name: Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem
Purity: Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
Packaging: 250μg
Price: $113
Updated: 2024/03/01

Sigma-Aldrich

Product number: 219007
Product name: Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem<br />Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
Packaging: 1mg
Price: $303
Updated: 2024/03/01

Cayman Chemical

Product number: 14467
Product name: Z-VAD(OH)-FMK
Purity: ≥95%
Packaging: 500μg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 14467
Product name: Z-VAD(OH)-FMK
Purity: ≥95%
Packaging: 1mg
Price: $131
Updated: 2024/03/01

Cayman Chemical

Product number: 14467
Product name: Z-VAD(OH)-FMK
Purity: ≥95%
Packaging: 5mg
Price: $380
Updated: 2024/03/01

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Z-Vad-fmk, non-methylated Chemical Properties,Usage,Production

Description

Z-VAD(OH)-FMK is an irreversible tripeptide inhibitor of all caspases. This non-methylated form is useful in studies involving recombinant, isolated, or purified enzymes. Unlike the methylated form, Z-VAD(OMe)-FMK , this compound does not require pretreatment with esterases prior to in vitro use.

General Description

An irreversible general caspase inhibitor. Useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I (Cat. No. 627610), this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 μl) solution of Caspase Inhibitor VI (Cat. No. 219011) in DMSO is also available.

Biochem/physiol Actions

Product does not compete with ATP.

Z-Vad-fmk, non-methylated Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-Vad-fmk, non-methylated Suppliers

China 54 United States 8 Global 62

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Sigma-Aldrich

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161401-82-7, Z-Vad-fmk, non-methylatedRelated Search:

ZT-12-037-01 (Z)-CAPSAICIN ZSTK474 Z-FA-FMK Z-PHE-DL-ALA-FLUOROMETHYLKETONE CASPASE-8 INHIBITOR II Z-DEVD-FMK Z-VAD-FMK

Z-VAD(OH)-FMK (Caspase Inhibitor VI)

Z-VAL-ALA-ASP-(OH)-FLUOROMETHYL KETONE

Z-VAD-FMK (Caspase Inhibitor VI)

Carbobenzyloxy-Val-Ala-Asp-alpha-fluoromethylketone

L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-

L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]- (9ci)

L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[1-(carboxymethyl)-3-fluoro-2-oxopropyl]-, (S)-

Z-VAD-FMK, Free Acid

Caspase Inhibitor VI - CAS 161401-82-7 - Calbiochem

abs817872

(5S,8S,11S)-11-(2-Fluoroacetyl)-5-isopropyl-8-methyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatridecan-13-oic acid

Z-VAD

inhibit,Inhibitor,ZVADFMK,Hela,Z VAD FMK,Caspase,Antiapoptosis,cells,pan-caspase

161401-82-7

C21H28FN3O7