ChemicalBook > CAS DataBase List > Abacavir Carboxylate
Abacavir Carboxylate
- Product Name
- Abacavir Carboxylate
- CAS No.
- 384380-52-3
- Chemical Name
- Abacavir Carboxylate
- Synonyms
- 2269W;Abacavir Impurity 14;Abacavir Carboxylate;(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-ene-1-carboxylic acid;(1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enecarboxylic acid;(1S,4R)-4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid;2-Cyclopentene-1-carboxylic acid, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-
- CBNumber
- CB42502991
- Molecular Formula
- C14H16N6O2
- Formula Weight
- 300.32
- MOL File
- 384380-52-3.mol
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Abacavir Carboxylate Property
- Melting point:
- 208-210°C (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
- form
- Solid
- color
- Off-White to Pale Beige
- Stability:
- Hygroscopic
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 27777
- Product name
- Abacavir Carboxylate
- Packaging
- 1mg
- Price
- $364
- Updated
- 2024/03/01
Usbiological
- Product number
- 295337
- Product name
- Abacavir carboxylate
- Packaging
- 1mg
- Price
- $633
- Updated
- 2021/12/16
TRC
- Product number
- A105005
- Product name
- AbacavirCarboxylate
- Packaging
- 10mg
- Price
- $1815
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- NA16897
- Product name
- Abacavir carboxylate
- Packaging
- 10mg
- Price
- $1950
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 18915
- Product name
- AbacavirCarboxylate
- Packaging
- 10mg
- Price
- $2700
- Updated
- 2021/12/16
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Abacavir Carboxylate Chemical Properties,Usage,Production
Description
Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir . It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues.
Chemical Properties
Off-White Solid
Uses
Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).
Definition
ChEBI: Abacavir 5'-carboxylic acid is a monocarboxylic acid oxidation product of abacavir, in which the C-5' hydroxymethyl group has been oxidised to a carboxy group. One of the two major metabolites of abacavir in humans (the other is the 5'-glucuronide, CHEBI:64189). It has a role as a metabolite. It is functionally related to an abacavir.
Abacavir Carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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Abacavir Carboxylate Suppliers
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384380-52-3, Abacavir CarboxylateRelated Search:
2,6-Diaminopurine
trans-Abacavir Hydrochloride
Abacavir
Abacavir
(1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride
(1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol
Abacavir sulfate
2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)-
Abacavir
2-Amino-6-cyclopropylamino-9H-purine
Abacavir
Abacavir 5'-Glucuronide
Abacavir 5’-Phosphate
Abacavir Related CoMpound D
Abacavir-d4
(1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride
6-aminocarbovir
Abacavir Impurity 1