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Abacavir

Product Name
Abacavir
CAS No.
783292-37-5
Chemical Name
Abacavir
Synonyms
Trans -Abacavir;(Abacavir EP Impurity D);Abacavir Impurity 4(Abacavir EP Impurity D);[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-;(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol
CBNumber
CB44656074
Molecular Formula
C14H18N6O
Formula Weight
286.33
MOL File
783292-37-5.mol
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Abacavir Property

Boiling point:
636.0±65.0 °C(Predicted)
Density 
1.70±0.1 g/cm3(Predicted)
pka
14.86±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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Abacavir Chemical Properties,Usage,Production

Uses

(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol (Abacavir EP Impurity D) is an impurity of Abacavir A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Abacavir Preparation Products And Raw materials

Raw materials

Preparation Products

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Abacavir Suppliers

Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
56902
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 17825480238
Fax
QQ 3008233717
Email
3008233717@qq.com
Country
China
ProdList
9919
Advantage
12
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.
Tel
020-89854820
Email
sales@jzpharma.cn
Country
China
ProdList
1080
Advantage
58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14332
Advantage
58
Jinan blalong chemical co. LTD
Tel
2710913286@.com
Email
1513643261@qq.com
Country
China
ProdList
14246
Advantage
58
Guangzhou Juntang Technology Co., Ltd
Tel
020-36607679 13502246435
Email
sales@dmstandards.com
Country
China
ProdList
10945
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58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12661
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58
Shenzhen Roark Pharma-Tec Co., Ltd.
Tel
13128912434
Email
2880126944@qq.com
Country
China
ProdList
2577
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58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
30961
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39004
Advantage
58

783292-37-5, AbacavirRelated Search:


  • Abacavir Impurity 4(Abacavir EP Impurity D)
  • (Abacavir EP Impurity D)
  • (1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol
  • [(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol
  • 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-
  • Trans -Abacavir
  • 783292-37-5