Abacavir

Product Name: Abacavir
CAS No.: 783292-37-5
Chemical Name: Abacavir
Synonyms: Trans -Abacavir;(Abacavir EP Impurity D);Abacavir Impurity 4(Abacavir EP Impurity D);[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-;(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol
CBNumber: CB44656074
Molecular Formula: C14H18N6O
Formula Weight: 286.33
MOL File: 783292-37-5.mol

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Abacavir Property

Boiling point:: 636.0±65.0 °C(Predicted)
Density: 1.70±0.1 g/cm3(Predicted)
pka: 14.86±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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Abacavir Chemical Properties,Usage,Production

Uses

(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol (Abacavir EP Impurity D) is an impurity of Abacavir A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Abacavir Preparation Products And Raw materials

Raw materials

Preparation Products

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Abacavir Suppliers

China 9 India 6 United States 1 Global 16

783292-37-5, AbacavirRelated Search:

Lamivudine Abacavir Carboxylate Abacavir-d4 Abacavir Abacavir 5’-Phosphate 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- trans-Abacavir Hydrochloride Abacavir 2,6-Diaminopurine 6-aminocarbovir (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride Abacavir Related CoMpound D Abacavir 2-Amino-6-cyclopropylamino-9H-purine Abacavir sulfate

Abacavir Impurity 4(Abacavir EP Impurity D)

(Abacavir EP Impurity D)

(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol

[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol

2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-

Trans -Abacavir

783292-37-5