Abacavir Carboxylate

Product Name: Abacavir Carboxylate
CAS No.: 384380-52-3
Chemical Name: Abacavir Carboxylate
Synonyms: 2269W;Abacavir Impurity 14;Abacavir Carboxylate;(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-ene-1-carboxylic acid;(1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enecarboxylic acid;(1S,4R)-4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid;2-Cyclopentene-1-carboxylic acid, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-
CBNumber: CB42502991
Molecular Formula: C14H16N6O2
Formula Weight: 300.32
MOL File: 384380-52-3.mol

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Abacavir Carboxylate Property

Melting point:: 208-210°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
form: Solid
color: Off-White to Pale Beige
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27777
Product name: Abacavir Carboxylate
Packaging: 1mg
Price: $364
Updated: 2024/03/01

Usbiological

Product number: 295337
Product name: Abacavir carboxylate
Packaging: 1mg
Price: $633
Updated: 2021/12/16

TRC

Product number: A105005
Product name: AbacavirCarboxylate
Packaging: 10mg
Price: $1815
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NA16897
Product name: Abacavir carboxylate
Packaging: 10mg
Price: $1950
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18915
Product name: AbacavirCarboxylate
Packaging: 10mg
Price: $2700
Updated: 2021/12/16

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Abacavir Carboxylate Chemical Properties,Usage,Production

Description

Abacavir carboxylate is an inactive metabolite of the HIV-1 reverse transcriptase inhibitor abacavir . It is formed from abacavir via reactive aldehyde intermediates that can form adducts with proteins on valine residues.

Chemical Properties

Off-White Solid

Uses

Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).

Definition

ChEBI: Abacavir 5'-carboxylic acid is a monocarboxylic acid oxidation product of abacavir, in which the C-5' hydroxymethyl group has been oxidised to a carboxy group. One of the two major metabolites of abacavir in humans (the other is the 5'-glucuronide, CHEBI:64189). It has a role as a metabolite. It is functionally related to an abacavir.

Abacavir Carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Abacavir Carboxylate Suppliers

Canada 1 China 18 India 5 United Kingdom 1 United States 4 Global 29

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384380-52-3, Abacavir CarboxylateRelated Search:

2,6-Diaminopurine trans-Abacavir Hydrochloride Abacavir Abacavir (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol Abacavir sulfate 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- Abacavir 2-Amino-6-cyclopropylamino-9H-purine Abacavir Abacavir 5'-Glucuronide Abacavir 5’-Phosphate Abacavir Related CoMpound D Abacavir-d4 (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride 6-aminocarbovir Abacavir Impurity 1

Abacavir Carboxylate

(1S,4R)-4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid

2269W

(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-ene-1-carboxylic acid

(1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enecarboxylic acid

2-Cyclopentene-1-carboxylic acid, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-

Abacavir Impurity 14

384380-52-3

Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals

Bases & Related Reagents

Intermediates & Fine Chemicals

Metabolites & Impurities

Nucleotides

Pharmaceuticals