Abacavir Related CoMpound D

Product Name: Abacavir Related CoMpound D
CAS No.: 1443421-69-9
Chemical Name: Abacavir Related CoMpound D
Synonyms: Abacavir EP Imp B;Abacavir Impurity B;Abacavir Impurity D;Abacavir EP Impurity B;ABACAVIR O-PYRIMIDYL IMP;Abacavir Related CoMpound D;O-Pyrimidine Derivative Abacavir (USP);Abacavir Impurity 2(Abacavir EP Impurity B);Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine;N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine
CBNumber: CB22714699
Molecular Formula: C18H21ClN10O
Formula Weight: 428.88
MOL File: 1443421-69-9.mol

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Abacavir Related CoMpound D Property

Boiling point:: 830.1±75.0 °C(Predicted)
Density: 1.90±0.1 g/cm3(Predicted)
pka: 4.86±0.10(Predicted)

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Safety

WGK Germany: 3
HS Code: 2933599550

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1000437
Product name: Abacavir Related Compound D
Packaging: 20mg
Price: $1360
Updated: 2024/03/01

TRC

Product number: A105035
Product name: Abacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine
Packaging: 25mg
Price: $1050
Updated: 2021/12/16

TRC

Product number: A105035
Product name: Abacavir5’-4-Chloro-6-methylpyrimidine-2,5-diamine
Packaging: 2.5mg
Price: $130
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0027217
Product name: ABACAVIR O-PYRIMIDINE IMPURITY
Purity: 95.00%
Packaging: 5MG
Price: $504.96
Updated: 2021/12/16

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Abacavir Related CoMpound D Chemical Properties,Usage,Production

Uses

Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Abacavir Related CoMpound D Preparation Products And Raw materials

Raw materials

Preparation Products

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Abacavir Related CoMpound D Suppliers

China 24 India 7 United States 4 Global 35

Shanghai CR Corporation Limited

Tel: 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 10108
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9506
Advantage: 60

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 0755-22202135 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 7692
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 2881290884@qq.com
Country: China
ProdList: 7493
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12382
Advantage: 58

CR Corporation Lomited

Tel
Email: fred.wen@crcorporation.cn
Country: CHINA
ProdList: 12069
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 17825480238
Fax: QQ 3008233717
Email: 3008233717@qq.com
Country: China
ProdList: 9844
Advantage: 12

Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.

Tel: 020-89854820
Email: sales@jzpharma.cn
Country: China
ProdList: 1072
Advantage: 58

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14336
Advantage: 58

1443421-69-9, Abacavir Related CoMpound DRelated Search:

Abacavir sulfate 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- Abacavir (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride 6-aminocarbovir Abacavir-d4 Abacavir Abacavir trans-Abacavir Hydrochloride 2-Amino-6-cyclopropylamino-9H-purine (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol 2,6-Diaminopurine Abacavir 5'-Glucuronide Abacavir Abacavir Carboxylate Abacavir 5’-Phosphate (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride Abacavir Impurity 1

Abacavir EP Imp B

Abacavir Related CoMpound D

N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine

Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine

Abacavir Impurity 2(Abacavir EP Impurity B)

Abacavir EP Impurity B

O-Pyrimidine Derivative Abacavir (USP)

6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(2,5-diamino-6-chloropyrimidin-4-yl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine

9H-Purine-2,6-diamine, N6-cyclopropyl-9-[(1R,4S)-4-[[(2,5-diamino-6-chloro-4-pyrimidinyl)oxy]methyl]-2-cyclopenten-1-yl]-

Abacavir Impurity D

Abacavir Impurity B

6-N-Cyclopropyl-9-[(1R,4S)-4-[[(2,5-diamino-6-chloro-4- pyrimidinyl)oxy]methyl]cyclopent-2-en-1-yl]-9H-purine-2,6- diamine

ABACAVIR O-PYRIMIDYL IMP

N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-Diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine (Abacavir Impurity)

Abacavir Related Compound D (20 mg) (N6-Cyclopropyl-9-{(1R,4S)-4-[(2,5-diamino-6-chloropyrimidin-4-yloxy)methyl]cyclopent-2-enyl}-9H-purine-2,6-diamine)

1443421-69-9

C18H21ClN10O