Abacavir

Product Name: Abacavir
CAS No.: 783292-37-5
Chemical Name: Abacavir
Synonyms: Trans -Abacavir;(Abacavir EP Impurity D);Abacavir Impurity 4(Abacavir EP Impurity D);[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-;(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol
CBNumber: CB44656074
Molecular Formula: C14H18N6O
Formula Weight: 286.33
MOL File: 783292-37-5.mol

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Abacavir Property

Boiling point:: 636.0±65.0 °C(Predicted)
Density: 1.70±0.1 g/cm3(Predicted)
pka: 14.86±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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Abacavir Chemical Properties,Usage,Production

Uses

(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol (Abacavir EP Impurity D) is an impurity of Abacavir A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Abacavir Preparation Products And Raw materials

Raw materials

Preparation Products

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Abacavir Suppliers

China 9 India 6 United States 1 Global 16

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57412
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 17825480238
Fax: QQ 3008233717
Email: 3008233717@qq.com
Country: China
ProdList: 9919
Advantage: 12

Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.

Tel: 020-89854820
Email: sales@jzpharma.cn
Country: China
ProdList: 1130
Advantage: 58

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14246
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10945
Advantage: 58

Foshan Treasure Biotechnology Co., Ltd

Tel: 0757-85921206 18520245316
Email: 2329783215@qq.com
Country: China
ProdList: 12661
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Shenzhen Roark Pharma-Tec Co., Ltd.

Tel: 13128912434
Email: 2880126944@qq.com
Country: China
ProdList: 2577
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: 18616537568
Email: hanfangpharma@126.com
Country: China
ProdList: 30961
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Suzhou ARTK Medchem Co., Ltd.

Tel: +86-512-68323658 +86-18168183658
Email: sales1@artkmedchem.com
Country: China
ProdList: 39004
Advantage: 58

783292-37-5, AbacavirRelated Search:

Lamivudine Abacavir Carboxylate Abacavir-d4 Abacavir Abacavir 5’-Phosphate 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R-cis)- trans-Abacavir Hydrochloride Abacavir 2,6-Diaminopurine 6-aminocarbovir (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol (1S–4R)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride Abacavir Related CoMpound D Abacavir 2-Amino-6-cyclopropylamino-9H-purine Abacavir sulfate

Abacavir Impurity 4(Abacavir EP Impurity D)

(Abacavir EP Impurity D)

(1R,?4R)?-?rel-4-?[2-Amino-?6-?(cyclopropylamino)?-?9H-?purin-?9-?yl]?-?2-?cyclopentene-?1-?methanol

[(1R,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol

2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4R)-rel-

Trans -Abacavir

783292-37-5