1H-1-Ethyl Candesartan Cilexetil

Product Name: 1H-1-Ethyl Candesartan Cilexetil
CAS No.: 914613-35-7
Chemical Name: 1H-1-Ethyl Candesartan Cilexetil
Synonyms: Candesartan EP Imp E;Candesartan Impurity 2;Candesartan EP Impurity-E;Candesartan Cilexetil impurity E;1H-1-Ethyl Candesartan Cilexetil;Candesartan Cilexetil EP IMpurity E;Candesartan Cilexetil Impurity 5(EP Impurity E);Candesartan Cilexetil Impurity 5(Candesartan Cilexetil EP Impurity E);2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;Candesartan Cilexetil EP Impurity E (Candesartan Cilexetil N1-Ethyl Analog)
CBNumber: CB42508599
Molecular Formula: C35H38N6O6
Formula Weight: 638.71282
MOL File: 914613-35-7.mol

More

Less

1H-1-Ethyl Candesartan Cilexetil Property

Melting point:: 90-93°C
Boiling point:: 842.0±75.0 °C(Predicted)
Density: 1.32
storage temp.: Refrigerator
solubility: ≤30mg/ml in DMSO;30mg/ml in dimethyl formamide
form: crystalline solid
pka: 3.95±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 17912
Product name: 1H-1-ethyl Candesartan Cilexetil
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 17912
Product name: 1H-1-ethyl Candesartan Cilexetil
Purity: ≥98%
Packaging: 5mg
Price: $220
Updated: 2024/03/01

Cayman Chemical

Product number: 17912
Product name: 1H-1-ethyl Candesartan Cilexetil
Purity: ≥98%
Packaging: 10mg
Price: $330
Updated: 2024/03/01

TRC

Product number: E900870
Product name: 1H-1-EthylCandesartanCilexetil
Packaging: 10mg
Price: $180
Updated: 2021/12/16

ApexBio Technology

Product number: C5023
Product name: 1H-1-ethylCandesartanCilexetil
Packaging: 10mg
Price: $374
Updated: 2021/12/16

More

Less

1H-1-Ethyl Candesartan Cilexetil Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Candesartan Cilexetil Impurity E (PHARMEUROPA).

Biological Activity

1h-1-ethyl candesartan cilexetil, which is a process-related impurity commonly found in the bulk synthesis of candesartan cilexetil, is a potent, long-acting, and selective angiotensin ii type 1 receptor (at1) antagonist.angiotensin ii is a peptide that is mainly generated by the angiotensin converting enzyme and chymase, which plays a vital role in regulating blood pressure and sodium homeostasis via specific receptors including at1[1]. at1, localized in the kidney, heart, brain, adrenal gland, adipocytes, vascular smooth muscle cells, platelets, and placenta, is a major component of the renin-angiotensin system. furthermore, at1 mediates the classical biological actions of angiotensin ii. also, at1 has seven helical transmembrane domains, which is the characteristic of the superfamily of g-protein-coupled receptors. carboxyl-terminal region structure of at1 plays important roles in receptor internalization, desensitization and phosphorylation [2].

References

[1]. otsuka, m. reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin ii type 1 receptor antagonist. thorax. 2004; 59(1): 31-38.
[2]. guo, d., sun, y., hamet, p., & inagami, t. the angiotensin ii type 1 receptor and receptor-associated proteins. cell research. 2001; 11(3): 165-180.

1H-1-Ethyl Candesartan Cilexetil Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1H-1-Ethyl Candesartan Cilexetil Suppliers

Canada 1 China 55 India 7 United States 11 Global 74

Hunan Zengda Biological Technology Co., LTD

Tel: 18711085600
Email: 1652923704@qq.com
Country: China
ProdList: 4583
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14059
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4969
Advantage: 50

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
Country: China
ProdList: 4685
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17994
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9911
Advantage: 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7725
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

More

Less

View Lastest Price from 1H-1-Ethyl Candesartan Cilexetil manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Candesartan Cilexetil EP Impurity E 914613-35-7
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-24

914613-35-7, 1H-1-Ethyl Candesartan CilexetilRelated Search:

3-Aminosalicylic acid O-Desetheyl Candesartan Ethyl Ester Trityl candesartan Candesartan O-Desethyl Candesartan Cilexetil 2,5-Dihydroxybenzoic acid Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate N-Trityl Candesartan Ethyl Ester Trityl candesartan cilexetil Candesartan Cilexetil Methoxy Analogue 2H-2-Ethyl Candesartan Cilexetil 2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) methyl] Candesartan Methyl Ester Desethyl Analog 5-(phenylazo)salicylic acid CV 15959 2-Desethoxy-2-hydroxy-2H-2-ethyl Candesartan Cilexetil Candesartan Cilexetil Impurity 17

1H-1-Ethyl Candesartan Cilexetil

Candesartan Cilexetil impurity E

Candesartan Impurity 2

2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 1H-benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester

2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-

Candesartan Cilexetil EP IMpurity E

Candesartan Cilexetil Impurity 5(EP Impurity E)

Candesartan EP Imp E

1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(1-ethyltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate

1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester

Candesartan Cilexetil EP Impurity E (Candesartan Cilexetil N1-Ethyl Analog)

Candesartan Cilexetil EP Impurity EQ: What is Candesartan Cilexetil EP Impurity E Q: What is the CAS Number of Candesartan Cilexetil EP Impurity E Q: What is the storage condition of Candesartan Cilexetil EP Impurity E Q: What are the applications of Candesartan Cilexetil EP Impurity E

Candesartan Cilexetil,1H1ethyl Candesartan Cilexetil,Inhibitor,1H 1 ethyl Candesartan Cilexetil,inhibit

Candesartan Cilexetil Impurity 5(Candesartan Cilexetil EP Impurity E)

(1RS)-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1- ethyl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7- carboxylate

Candesartan EP Impurity-E

1-(((Cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'- (1-ethyl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)- 1H-benzo[d]imidazole-7-carboxylate

914613-35-7

Aromatics

Heterocycles

Impurities

Intermediates & Fine Chemicals

Pharmaceuticals