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Indacaterol interMediate

Product Name
Indacaterol interMediate
CAS No.
435273-75-9
Chemical Name
Indacaterol interMediate
Synonyms
Benzyl Indacaterol;Indacaterol Impurity 8;Indacaterol maleate impurity A;2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-ind...;(R)-8-benzyloxy-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one;(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-;(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1;(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one;(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-;(R)-8-(benzyloxy)-5-(2-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylaMino)-1-hydroxyethyl)quinolin-2(1H)-one
CBNumber
CB42566366
Molecular Formula
C31H34N2O3
Formula Weight
482.61
MOL File
435273-75-9.mol
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Indacaterol interMediate Property

Melting point:
78-82°C
Boiling point:
734.1±60.0 °C(Predicted)
Density 
1.23
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.86±0.70(Predicted)
color 
Off-White to Pale Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
D444238
Product name
5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone
Packaging
1mg
Price
$135
Updated
2021/12/16
TRC
Product number
D444238
Product name
5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone
Packaging
2.5mg
Price
$295
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0000930
Product name
(R)-8-(BENZYLOXY)-5-(2-((5,6-DIETHYL-2,3-DIHYDRO-1H-INDEN-2-YL)AMINO)-1-HYDROXYETHYL)QUINOLIN-2(1H)-ONE
Purity
95.00%
Packaging
5MG
Price
$495
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD137625
Product name
(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)quinolin-2(1H)-one
Packaging
1g
Price
$500
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD137625
Product name
(R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)quinolin-2(1H)-one
Packaging
2g
Price
$600
Updated
2021/12/16
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Indacaterol interMediate Chemical Properties,Usage,Production

Uses

5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone is used as a reactant in the preparation of Indacaterol (I499745), a β-adrenoreceptor agonist.

Indacaterol interMediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Indacaterol interMediate Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

435273-75-9, Indacaterol interMediateRelated Search:


  • (R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)aMino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one
  • (R)-5-[2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)quinolin-2(1H)-one
  • (R)-8-benzyloxy-5-[2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-1H-quinolin-2-one
  • 5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-phenylmethoxy-1H-quinolin-2-one
  • (R)-8-(benzyloxy)-5-(2-(5,6-diethyl-2,3-dihydro-1H-inden-2-ylaMino)-1-hydroxyethyl)quinolin-2(1H)-one
  • (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1
  • (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-
  • Indacaterol Impurity 8
  • 2(1H)-Quinolinone,5-[(1R)-2-[( 5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)
  • (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-on
  • 5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone
  • 2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-ind...
  • Indacaterol maleate impurity A
  • (R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-
  • Benzyl Indacaterol
  • (R) -5- [2- [(5,6-diethyl-2,3-dihydro-1H-inde-2-yl) amino] -1-hydroxyethyl] -8- (benzyloxy) -2 (1H) - quinolone
  • 435273-75-9