3-Amino-4-methylbenzonitrile
- Product Name
- 3-Amino-4-methylbenzonitrile
- CAS No.
- 60710-80-7
- Chemical Name
- 3-Amino-4-methylbenzonitrile
- Synonyms
- 3-Amino-p-tolunitrile;2-Amino-4-cyanotoluene;3-AMINO-4-METHYLBENZONITRILE;Benzonitrile, 3-amino-4-methyl-;3-Amino-4-methylbenzonitrile 98%;5-Cyano-2-methylaniline, 2-Amino-4-cyanotoluene
- CBNumber
- CB4257974
- Molecular Formula
- C8H8N2
- Formula Weight
- 132.16
- MOL File
- 60710-80-7.mol
3-Amino-4-methylbenzonitrile Property
- Melting point:
- 81 °C
- Boiling point:
- 312.8±22.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2?+-.0.10(Predicted)
- form
- crystals
- color
- White to off white to clear shards
- InChI
- InChI=1S/C8H8N2/c1-6-2-3-7(5-9)4-8(6)10/h2-4H,10H2,1H3
- InChIKey
- IEWMNQUBZPVSSV-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC=C(C)C(N)=C1
- CAS DataBase Reference
- 60710-80-7(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- A898175
- Product name
- 3-Amino-4-methylbenzonitrile
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA70488
- Product name
- 3-Amino-4-methylbenzonitrile
- Packaging
- 25g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FA70488
- Product name
- 3-Amino-4-methylbenzonitrile
- Packaging
- 50g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- OR4824
- Product name
- 3-Amino-4-methylbenzonitrile
- Purity
- 98%
- Packaging
- 100g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- FA70488
- Product name
- 3-Amino-4-methylbenzonitrile
- Packaging
- 100g
- Price
- $230
- Updated
- 2021/12/16
3-Amino-4-methylbenzonitrile Chemical Properties,Usage,Production
Chemical Properties
off-white crystalline
Uses
3-Amino-4-methylbenzonitrile is an organic compound commonly used as an intermediate in organic synthesis, especially in pharmaceutical and pesticide chemistry.
Synthesis
939-79-7
60710-80-7
C.14.b. Synthesis of 3-amino-4-methylbenzonitrile: 120 g of 3-nitro-4-methylbenzonitrile was suspended in 1.2 L of ethanol, and 7 g of 10% Pd/C catalyst was added and the hydrogenation reaction was carried out in a 50 L hydrogen atmosphere at room temperature. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration, followed by distillation under reduced pressure to remove the solvent to afford 95 g of pure 3-amino-4-methylbenzonitrile in 97% yield. The product was characterized by 1H-NMR (DMSO-d6; δ, ppm): 7.1 (dd, 1H); 6.90 (d, 1H); 6.85 (d, 1H); 5.35 (s, 2H, NH2); 2.15 (s, 3H).
References
[1] Patent: US6455671, 2002, B1
[2] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 8, p. 1203 - 1208
[3] Chemische Berichte, 1903, vol. 36, p. 4359
[4] Chemische Berichte, 1904, vol. 37, p. 1845
[5] Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 1997, vol. 53, # 2, p. 141 - 150
3-Amino-4-methylbenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
3-Amino-4-methylbenzonitrile Suppliers
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View Lastest Price from 3-Amino-4-methylbenzonitrile manufacturers
- Product
- 3-AMINO-4-METHYLBENZONITRILE 60710-80-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-22
- Product
- 3-AMINO-4-METHYLBENZONITRILE 60710-80-7
- Price
- US $0.00-0.00/kg T
- Min. Order
- 1kg T
- Purity
- 99.9%MIN
- Supply Ability
- 20TONS
- Release date
- 2023-03-20