Piperazine citrate
- Product Name
- Piperazine citrate
- CAS No.
- 144-29-6
- Chemical Name
- Piperazine citrate
- Synonyms
- ANTEPAR;Pinozan;PARAZINE;Patazine;Piperasol;Citraazine;Coliurinal;PIPERAZINE CITRATE;PiperazineCitrateBp;Tripiperazindicitrat
- CBNumber
- CB4258805
- Molecular Formula
- C24H46N6O14
- Formula Weight
- 642.65
- MOL File
- 144-29-6.mol
Piperazine citrate Property
- Melting point:
- 183-187℃
- Boiling point:
- 208℃[at 101 325 Pa]
- Density
- 0.741[at 20℃]
- vapor pressure
- 56.928Pa
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in DMSO
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- 54g/L at 24℃
- Merck
- 14,7464
- LogP
- -1.15
- CAS DataBase Reference
- 144-29-6(CAS DataBase Reference)
- EPA Substance Registry System
- Piperazine, 2-hydroxy-1,2,3-propanetricarboxylate (3:2) (144-29-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P2000000
- Product name
- Piperazine citrate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- P2000000
- Price
- $150
- Updated
- 2024/03/01
- Product number
- P0449
- Product name
- Piperazine Citrate Hydrate
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $31
- Updated
- 2024/03/01
- Product number
- P0449
- Product name
- Piperazine Citrate Hydrate
- Purity
- >98.0%(T)
- Packaging
- 500g
- Price
- $71
- Updated
- 2024/03/01
- Product number
- P479890
- Product name
- Piperazine citrate
- Packaging
- 25g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- P479890
- Product name
- Piperazine citrate
- Packaging
- 100g
- Price
- $275
- Updated
- 2021/12/16
Piperazine citrate Chemical Properties,Usage,Production
Description
Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.
Chemical Properties
Piperazine citrate is a white, crystalline powder, with not more than a slight odor. It is soluble in water, and insoluble in alcohol and in ether.
Uses
Piperazine Citrate is an anthelmintic agent used in the treatment of parasitic infections. Also used in the reduction of blood pressure.
Indications
Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.
brand name
Antepar (GlaxoSmithKline); Bryrel (Sanofi Aventis).
Flammability and Explosibility
Not classified
Mechanism of action
Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.
Pharmacokinetics
Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.
Piperazine citrate Preparation Products And Raw materials
Raw materials
Preparation Products
Piperazine citrate Suppliers
- Tel
- 0531-0531-88895833 15552594168
- 2509590879@qq.com
- Country
- China
- ProdList
- 208
- Advantage
- 58
- Tel
- 0531-88996911 15628983711
- Fax
- 0531-88996911
- 3305202763@qq.com
- Country
- China
- ProdList
- 125
- Advantage
- 58
- Tel
- +86-29-88665278 13379235092
- sales@vedachem.com
- Country
- China
- ProdList
- 48
- Advantage
- 58
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- +86-28-86127071
- Fax
- +86-28-86127072
- info@sino-produce.com
- Country
- China
- ProdList
- 406
- Advantage
- 66
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14103
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
View Lastest Price from Piperazine citrate manufacturers
- Product
- Piperazine citrate 144-29-6
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98.5%min
- Supply Ability
- 10 TONS
- Release date
- 2021-06-24
- Product
- PIPERAZINE CITRATE 144-29-6
- Price
- US $33.00/KG
- Min. Order
- 100KG
- Purity
- 98%
- Supply Ability
- 1-200mt
- Release date
- 2021-06-08
- Product
- PIPERAZINE CITRATE 144-29-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-11