Piperazine citrate

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Piperazine citrate

Product Name: Piperazine citrate
CAS No.: 144-29-6
Chemical Name: Piperazine citrate
Synonyms: ANTEPAR;Pinozan;PARAZINE;Patazine;Piperasol;Citraazine;Coliurinal;PIPERAZINE CITRATE;PiperazineCitrateBp;Tripiperazindicitrat
CBNumber: CB4258805
Molecular Formula: C24H46N6O14
Formula Weight: 642.65
MOL File: 144-29-6.mol

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Piperazine citrate Property

Melting point:: 183-187℃
Boiling point:: 208℃[at 101 325 Pa]
Density: 0.741[at 20℃]
vapor pressure: 56.928Pa
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in DMSO
form: powder to crystal
color: White to Almost white
Water Solubility: 54g/L at 24℃
Merck: 14,7464
LogP: -1.15
CAS DataBase Reference: 144-29-6(CAS DataBase Reference)
EPA Substance Registry System: Piperazine, 2-hydroxy-1,2,3-propanetricarboxylate (3:2) (144-29-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 1
RTECS: TL3485000
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P2000000
Product name: Piperazine citrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: P2000000
Price: $150
Updated: 2024/03/01

TCI Chemical

Product number: P0449
Product name: Piperazine Citrate Hydrate
Purity: >98.0%(T)
Packaging: 25g
Price: $31
Updated: 2024/03/01

TCI Chemical

Product number: P0449
Product name: Piperazine Citrate Hydrate
Purity: >98.0%(T)
Packaging: 500g
Price: $71
Updated: 2024/03/01

TRC

Product number: P479890
Product name: Piperazine citrate
Packaging: 25g
Price: $140
Updated: 2021/12/16

TRC

Product number: P479890
Product name: Piperazine citrate
Packaging: 100g
Price: $275
Updated: 2021/12/16

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Piperazine citrate Chemical Properties,Usage,Production

Description

Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.

Chemical Properties

Piperazine citrate is a white, crystalline powder, with not more than a slight odor. It is soluble in water, and insoluble in alcohol and in ether.

Uses

Piperazine Citrate is an anthelmintic agent used in the treatment of parasitic infections. Also used in the reduction of blood pressure.

Indications

Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.

brand name

Antepar (GlaxoSmithKline); Bryrel (Sanofi Aventis).

Flammability and Explosibility

Not classified

Mechanism of action

Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.

Pharmacokinetics

Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.

Piperazine citrate Preparation Products And Raw materials

Raw materials

PIPERAZINE HEXAHYDRATE Piperazine

Preparation Products

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View Lastest Price from Piperazine citrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Piperazine citrate 144-29-6
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98.5%min
Supply Ability: 10 TONS
Release date: 2021-06-24

Baoji Guokang Bio-Technology Co., Ltd.

Product: PIPERAZINE CITRATE 144-29-6
Price: US $33.00/KG
Min. Order: 100KG
Purity: 98%
Supply Ability: 1-200mt
Release date: 2021-06-08

Hebei Weibang Biotechnology Co., Ltd

Product: PIPERAZINE CITRATE 144-29-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-11

144-29-6, Piperazine citrateRelated Search:

Disodium citrate Sodium citrate CITRIC ACID ISOPROPYL ESTER Calcium citrate Potassium Citrate Sodium ferrous citrate Triethyl citrate Ammonium citrate dibasic BETAINE CITRATE POTASSIUM DIHYDROGEN CITRATE DISODIUM HYDROGEN CITRATE SESQUIHYDRATE AMMONIUM BISMUTH CITRATE Maropitant citrate hydrate MAGNESIUM CITRATE 2-Hydroxy-1,2,3-propanetricarboxylic acid/ammonia,(1:x) Trisodium citrate dihydrate PIPERAZINE CITRATE HYDRATE,PIPERAZINE CITRATE N-HYDRATE,piperazine,citrate(3:2 Piperazine citrate

ANTEPAR

CITRIC ACID SESQUIPIPERAZINE SALT

PIPERAZINE CITRATE

PIPERAZINE CITRATE SALT

PARAZINE

TRIPIPERAZINE DICITRATE

PiperazineCitrateBp

Tripiperazindicitrat

PIPERAZINE CITARATE SALT

PIPERAZINE CITRATE / TRIPIPERAZINE DICITRATE

Citric acid hydrate sesquipiperazine salt

3Piperazine·2citric acid

PiperazineCitrate，Piperazine Citrate

Piperazine Citrate (200 mg)

Citraazine

Coliurinal

Patazine

Pinozan

Piperasol

piperazine 2-hydroxypropane-1,2,3-tricarboxylate

Piperazidine citrate

PIPERAZIN CITRATE HYDRATE

Piperazine citrate CRS

PiperazineCitrateHydrate&gt

PIPERAZINE CITRATE ISO 9001：2015 REACH

Pharmaceutical Intermediate Citrate Hydrate CAS?144-29-6

Piperazine citrate (P2000000)

Piperazine Citrate (1541805)

Piperazine citrate,inhibit,Piperazine,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,Inhibitor,1,4-Diazacyclohexane,GABA Receptor

Piperazine Citrate Hydrate, ≥ 98.0%

144-29-6

C12H30N62C6H8O7xH2O

C12H30N6C12H16O14xH2O

C4H10N232C6H8O7

C24H46N6O14

C12H30N62C6H8O7

C6H8O732C4H10N2

2C6H8O73C4H10N2

Piperazines

Heterocyclic Building Blocks

Building Blocks

API

Piperidines, Piperidones, Piperazines