5-Hydroxy-3,4-dihydroquinolin-2(1H)-one

Product Name: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one
CAS No.: 30389-33-4
Chemical Name: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one
Synonyms: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one;5-Hydroxy-3,4-dihydrocarbostyryl;Carteolol EP Impurity B;5-HYDROXY-3;Carteolol int;Carteolol Impurity 2;Carteolol Intermediate;Aripiprazole impurity 7;Aripiprazole Impurity 14;Brexpiprazole Impurity 70
CBNumber: CB4259600
Molecular Formula: C9H9NO2
Formula Weight: 163.17
MOL File: 30389-33-4.mol

More

Less

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Property

Melting point:: 225-227°C
Boiling point:: 381.2±42.0 °C(Predicted)
Density: 1.282±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 9.63±0.20(Predicted)
color: White to Off-White
InChI: InChI=1S/C9H9NO2/c11-8-3-1-2-7-6(8)4-5-9(12)10-7/h1-3,11H,4-5H2,(H,10,12)
InChIKey: UTTJAIFHRUAFED-UHFFFAOYSA-N
SMILES: N1C2=C(C(O)=CC=C2)CCC1=O
CAS DataBase Reference: 30389-33-4(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
HS Code: 2933499090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: D5669
Product name: 3,4-Dihydro-5-hydroxy-1H-quinolin-2-one
Packaging: 1G
Price: $56
Updated: 2024/03/01

TCI Chemical

Product number: D5669
Product name: 3,4-Dihydro-5-hydroxy-1H-quinolin-2-one
Packaging: 5G
Price: $278
Updated: 2024/03/01

TRC

Product number: H941410
Product name: 5-Hydroxy-3,4-dihydro-2(1H)-quinolinone
Packaging: 5g
Price: $425
Updated: 2021/12/16

Ark Pharm

Product number: P000281586
Product name: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one
Purity: 97%
Packaging: 250mg
Price: $15
Updated: 2021/12/16

Ark Pharm

Product number: P000281586
Product name: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one
Purity: 97%
Packaging: 1g
Price: $28
Updated: 2021/12/16

More

Less

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Chemical Properties,Usage,Production

Chemical Properties

Off-white Solid

Uses

Carteolol (C184450) metabolite.

Definition

ChEBI: 5-hydroxy-3,4-dihydro-2(1h)-quinolinone is a quinolone and a hydroxyquinoline.

Synthesis

To a 100 ml three-necked flask were added 3,4,7,8-tetrahydro-2,5 (1 H, 6Η) -quinoline dione (0.02 mol) and cyclohexane (25 ml). After stirring to dissolve in the ice bath for 10min, slowly add a dropwise N-bromosuccinimide (0.03mol) in cyclohexane (5ml), and reflux for 3h at the end of the dropwise addition. After completion of the reaction by TLC, cool down to room temperature. Water was added (the amount was 0.7 times the volume of the reactant), and the mixture was allowed to stand with stirring. The aqueous layer was extracted with ethyl acetate (1 × the volume of the aqueous layer 4 times), and the organic layers were combined. Anhydrous sulfuric acid Calcium was dried and filtered, the filtrate was evaporated to remove the solvent, and the residue was dried to give an off-white solid as a 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one (Yield 92.7percent).

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one Suppliers

Americas 1 Canada 1 China 170 Europe 1 India 11 Japan 2 Slovakia 1 Ukraine 1 United Kingdom 4 United States 21 Global 213

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 19943
Advantage: 58

Standardpharm Co. Ltd.

Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14332
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81215950 4000-868-328
Email: customer@uwalab.com
Country: United States
ProdList: 10404
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

AlliChem, LLC

Tel: --
Fax: --
Email: sales@allichemllc.com
Country: United States
ProdList: 6516
Advantage: 60

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Fragmenta

Tel: --
Fax: --
Email: sales@fragmenta.com
Country: United States
ProdList: 1068
Advantage: 0

Wilshire Chemical Company Inc.

Tel: --
Fax: --
Email: WilshrChem@AOL.COM
Country: United States
ProdList: 3498
Advantage: 58

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

Sinova Inc.

Tel: --
Fax: --
Email: sales@sinovainc.com
Country: United States
ProdList: 4009
Advantage: 58

Aagile Labs Division of Tyger Scientific

Tel: --
Fax: --
Email: tygersci@yahoo.com
Country: United States
ProdList: 6568
Advantage: 68

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

Davos Chemical Corporation

Tel: --
Fax: --
Email: info@davos.com
Country: United States
ProdList: 1640
Advantage: 65

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

More

Less

View Lastest Price from 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: 5-Hydroxy-3,4-dihydroquinolin-2(1H)-one 30389-33-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99% HPLC
Supply Ability: 1000kg
Release date: 2022-11-08

Zibo Hangyu Biotechnology Development Co., Ltd

Product: 5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 30389-33-4
Price: US $65.00-650.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-10-20

Shaanxi Dideu Medichem Co. Ltd

Product: 5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE 30389-33-4
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-24

30389-33-4, 5-Hydroxy-3,4-dihydroquinolin-2(1H)-oneRelated Search:

5-HYDROXY-2(1H)-QUINOLINONE 8-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane BroMide 7-Hydroxyquinolinone 7-(4-BROMOBUTOXY)-QUINOLINE-2(1H)-ONE Brexpiprazole Impurity 20 Thianaphthene Brexpiprazole Impurity Brexpiprazole Impurity 2 7-(4-chlorobutoxy)-1-{4-[(2-oxo-1,2-dihydroquinolin-7-yl)oxy]butyl}-1,2-dihydroquinolin-2-one Brexpiprazole sulfoxide impurity (E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE 1.1'-Binaphthyl-2.2'-diphemyl phosphine 8-hydroxy-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one 4-BROMO-BENZO[B]THIOPHENE 7,7'-(butane-1,4-diylbis(oxy))bis(quinolin-2(1H)-one) 2(1H)-Quinolinone,7-(4-chlorobutoxy)- Brexpiprazole (3,4)-Dihydro-2(1H)-quinolinone 1,4-di(benzo[b]thiophen-4-yl)piperazine

3,4-DIHYDRO-5-HYDROXY-2(1H)-QUINOLINONE

5-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE

5-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE

3,4-Dihydro-5-hydroxycarbostyril

5-HYDROXY-3,4-DIHYDRO-2-QUINOLINE

5-Hydroxy-2(1H)-3,4-dihydroquinolinone

3,4-Dihydro-5-hydroxy-1H-quinolin-2-one

5-Hydroxy-3,4-dihydrocarbostyril

3,4-Dihydro-5-hydroxyquinolin-2(1H)-one

5-Hydroxy-1,2,3,4-tetrahydroquinoline-2-one

5-hydroxy-1,2,3,4-tetrahydro-2-quinolinone

Carteolol int

Brexpiprazole Impurity 70

5-hydroxy-1,2,3,4-tetrahydroquinolin-2-one

5-Hydroxy-3,4-dihydrocarbostyryl

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one

2(1H)-Quinolinone, 3,4-dihydro-5-hydroxy-

Carteolol HCl EP Impurity B

Carbostyril,3,4-dihydro-5-hydroxy- (8CI)

Aripiprazole Impurity 14

Carteolol Intermediate

5-Hydroxy-3,4-dihydroquinolin-2(1H)

Aripiprazole impurity 7

Carteolol Hydrochloride impurity B

Carteolol EP Impurity B

5-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline

5-Hydroxy-3,4-dihydroquinolin-2(1H)-one(For export only)

4-DIHYDRO-1H-QUINOLIN-2-ONE

5-HYDROXY-3

5-hydroxy-3,4-dihydro-1-h-quinoline

Aripiprazole impurities1768

Carteolol Impurity 2

Carteolol EP Impurity B（Aripiprazole Impurity 26）

5-Hydroxy-3,4-dihydro-2(1H)-quinolinone (5-HQ)

5-Hydroxy-3,4-dihydro-2(1h)- quinolinone, 98% (Custom work)

30389-33-4

pharmacetical

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

API