ChemicalBook > CAS DataBase List > Mal-PEG2-COOH

Mal-PEG2-COOH

Product Name: Mal-PEG2-COOH
CAS No.: 756525-98-1
Chemical Name: Mal-PEG2-COOH
Synonyms: Mal-NH-PEG2-CH2CH2COOH;Mal-PEG2-COOH;MAL-dPEG2-acid;BMPA-PEG2-Acid;MAL-dPEG??-acid;Mal-NH-PEG2-COOH;MAL-AMIDO-PEG2-COOH;Mal-amido-PEG2-acid;Mal-amido-PEG2-C2-acid;Mal-amido-PEG2-NHS ester
CBNumber: CB42603836
Molecular Formula: C14H20N2O7
Formula Weight: 328.32
MOL File: 756525-98-1.mol

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Mal-PEG2-COOH Property

Boiling point:: 617.3±55.0 °C(Predicted)
Density: 1.318±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, stored under nitrogen
solubility: Soluble in DMSO
pka: 4.28±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Apolloscientific

Product number: BIPG1472
Product name: Mal-amido-PEG2-acid
Packaging: 250mg
Price: $131
Updated: 2021/12/16

BroadPharm

Product number: BP-22212
Product name: Mal-amido-PEG2-acid
Purity: 97%
Packaging: 100mg
Price: $160
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG1555
Product name: mal-PEG(2)-COOH
Packaging: 100mg
Price: $202.5
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1472
Product name: Mal-amido-PEG2-acid
Packaging: 500mg
Price: $232
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG1555
Product name: mal-PEG(2)-COOH
Packaging: 1g
Price: $270
Updated: 2021/12/16

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Mal-PEG2-COOH Chemical Properties,Usage,Production

Description

Mal-amido-PEG2-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG2-COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mal-PEG2-COOH manufacturers

LAURENT

Product: Mal-NH-PEG2-CH2CH2COOH 756525-98-1
Price: US $321.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 300kg
Release date: 2025-11-17

Career Henan Chemica Co

Product: Mal-PEG2-COOH 756525-98-1
Price: US $3.37/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10kg,100kg
Release date: 2020-11-06

Xian confluore Biological Technology Co., Ltd.

Product: Mal-amido-PEG2-acid 756525-98-1
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-27

756525-98-1, Mal-PEG2-COOHRelated Search:

Mal-PEG5-NHS ester Maleimido-Tri(Ethylene Glycol)-Propionic Acid N-[4-(-Carboxycyclohexylmethyl)]maleimide Mal-PEG4-Acid Mal-PEG2-NHS ester Bis-Mal-Lysine-PEG4-TFP ester 3-Maleimidopropionic acid Mal-PEG2-acid Mal-Amido-PEG4-acid 2-MALEIMIDOETHYLAMINE HCL alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Mal-PEG6-COOH alpha-MaleiMidopropionyl-oMega-succiniMidyl-12(ethylene glycol) MaleiMide-NH-PEG8-CH2CH2COOPFE Ester Mal-PEG8-COOH Maleimide-PEG4-NHS Ester Maleimide-PEG2-NHS Ester alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol)

Mal-PEG2-COOH

Mal-amido-PEG2-acid

3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid

Maleimide-NH-PEG2-CH2CH2COOH

Maleimide-PEG2-propionic acid

MAL-AMIDO-PEG2-COOH

Mal-NH-PEG2-COOH

Mal-NH-PEG2-CH2CH2COOH

Mal-amido-PEG2-NHS ester

Mal-amido-PEG2-C2-acid

Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-

Mal-amido-PEG2-propionic acid

MAL-dPEG??-acid

MAL-dPEG2-acid

Mal-CH2CH2CONH-PEG2-CH2CH2COOH

BMPA-PEG2-Acid

Mal-CH2CH2CONH-PEG2-CH2CH2COOH/Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-

3-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]propanoic acid

MAL-dPEG??-acid (QBD-10265)

3-[2-[2-[3-(2,5-Dioxo-2,5-dihydro-1-pyrrolyl)propanamido]ethoxy]ethoxy]propionic Acid

756525-98-1

756525-97-1

Heterobifunctional PEG

peg