(-)-Variabilin
- Product Name
- (-)-Variabilin
- CAS No.
- 370102-93-5
- Chemical Name
- (-)-Variabilin
- Synonyms
- (-)-VARIABILIN;(6aS,11aS)-3,9-Dimethoxy-6H-benzofuro[3,2-c][1]benzopyran-6a(11aH)-ol;6H-Benzofuro[3,2-c][1]benzopyran-6a(11aH)-ol, 3,9-dimethoxy-, (6aS,11aS)-
- CBNumber
- CB42611163
- Molecular Formula
- C17H16O5
- Formula Weight
- 300.31
- MOL File
- 370102-93-5.mol
(-)-Variabilin Property
- Boiling point:
- 456.7±45.0 °C(Predicted)
- Density
- 1.351±0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 12.21±0.20(Predicted)
N-Bromosuccinimide Price
- Product number
- CFN97945
- Product name
- (-)-Variabilin
- Packaging
- 5mg
- Price
- $553
- Updated
- 2021/12/16
- Product number
- CD32001531
- Product name
- (-)-Variabilin
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $860
- Updated
- 2021/12/16
(-)-Variabilin Chemical Properties,Usage,Production
Description
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3. Variabilin is an inhibitor of human secretory and cytosolic phospholipase A2 (PLA2) activities that controls eicosanoid production in vitro and in vivo, inhibits neutrophil degranulation and superoxide generation in vitro and shows anti-inflammatory activity after topical or p.o. administration to mice. 3. Variabilin is an antimicrobial furanosesterterpene. 4. Variabilin is an important chemotaxonomic marker for the family Irciniidae.
Uses
(-)-Variabilin (compound 13) is an Neurogenin2 (Ngn2) promoter activator isolated from Butea superba. (-)-Variabilin promotes differentiation of neural stem cells into neurons[1].
target
Phospholipase (e.g. PLA) | Immunology & Inflammation related
References
[1] Midori A Arai, et al. Naturally occurring Ngn2 promoter activators from Butea superba. Mol Biosyst. 2013, 9, 10. DOI:10.1039/c3mb70083f
(-)-Variabilin Preparation Products And Raw materials
Raw materials
Preparation Products
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