ChemicalBook > CAS DataBase List > (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

Product Name
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CAS No.
870281-86-0
Chemical Name
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Synonyms
CAL10;CAL-101(N-1);Idelalisib INT;IdelalisibIntermediates 1;CAL-101 (N-1) Intermediate;(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone;4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-;2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one;(S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CBNumber
CB42623630
Molecular Formula
C17H16FN3O
Formula Weight
297.33
MOL File
870281-86-0.mol
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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Property

Boiling point:
455.3±55.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
form 
Solid
pka
8.23±0.29(Predicted)
color 
Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A628755
Product name
2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging
1g
Price
$180
Updated
2021/12/16
TRC
Product number
A628755
Product name
2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging
2.5g
Price
$275
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA96431
Product name
2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging
500mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA96431
Product name
2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging
1g
Price
$82
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA96431
Product name
2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging
2g
Price
$130
Updated
2021/12/16
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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Chemical Properties,Usage,Production

Uses

2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Suppliers

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View Lastest Price from (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 870281-86-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Career Henan Chemical Co
Product
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 870281-86-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-08-20

870281-86-0, (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-oneRelated Search:

Idelalisib Impurity 8 2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride 2-Amino-6-fluorobenzoic acid BOC-ABU-OH (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate CAL-101 2-Fluoro-6-nitro-N-phenylbenzamide

  • (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
  • 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
  • Idelalisib INT
  • CAL-101 (N-1) Intermediate
  • (S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
  • CAL10
  • IdelalisibIntermediates 1
  • 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one
  • CAL-101(N-1)
  • 4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-
  • 870281-86-0
  • intermediate
  • intermediates