(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

ChemicalBook > CAS DataBase List > (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

Product Name: (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CAS No.: 870281-86-0
Chemical Name: (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Synonyms: CAL10;CAL-101(N-1);Idelalisib INT;IdelalisibIntermediates 1;CAL-101 (N-1) Intermediate;(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone;4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-;2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one;(S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CBNumber: CB42623630
Molecular Formula: C17H16FN3O
Formula Weight: 297.33
MOL File: 870281-86-0.mol

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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Property

Boiling point:: 455.3±55.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
form: Solid
pka: 8.23±0.29(Predicted)
color: Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A628755
Product name: 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging: 1g
Price: $180
Updated: 2021/12/16

TRC

Product number: A628755
Product name: 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging: 2.5g
Price: $275
Updated: 2021/12/16

AK Scientific

Product number: 2965AH
Product name: (S)-2-(1-Aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Packaging: 1g
Price: $323
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA96431
Product name: 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging: 5G
Price: $220
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA96431
Product name: 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone
Packaging: 10g
Price: $270
Updated: 2021/12/16

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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Chemical Properties,Usage,Production

Uses

2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 870281-86-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Career Henan Chemical Co

Product: (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 870281-86-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

870281-86-0, (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-oneRelated Search:

Idelalisib Impurity 8 2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride 2-Amino-6-fluorobenzoic acid BOC-ABU-OH (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate CAL-101 2-Fluoro-6-nitro-N-phenylbenzamide

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone

Idelalisib INT

CAL-101 (N-1) Intermediate

(S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

CAL10

IdelalisibIntermediates 1

2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one

CAL-101(N-1)

4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-

870281-86-0

intermediate

intermediates