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Cefoselis sulfate

Product Name
Cefoselis sulfate
CAS No.
122841-12-7
Chemical Name
Cefoselis sulfate
Synonyms
Winsef;FK 037;FK 037 Sulfate;CEFOSELIS SULFATE;Cefoselis Sulfate (FK-037);Cefoselis sulfate USP/EP/BP;7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[2-(2-hydroxyethyl)-3-imino-1-pyrazolyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R,E)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydropyrazol-1-yl)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, sulfate;(6R-(6alpha,7beta(Z)))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid sulfate;(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydro-1H-pyrazol-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfate (1:1) (salt)
CBNumber
CB4263737
Molecular Formula
C19H24N8O10S3
Formula Weight
620.63
MOL File
122841-12-7.mol
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Cefoselis sulfate Property

storage temp. 
4°C, protect from light, stored under nitrogen
solubility 
DMSO : 100 mg/mL (161.12 mM; Need ultrasonic)H2O : 14.29 mg/mL (23.02 mM; Need ultrasonic)
form 
Powder
color 
White to off-white
CAS DataBase Reference
122841-12-7(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific
Product number
O697
Product name
Cefoselissulfate
Packaging
1mg
Price
$38
Updated
2021/12/16
ChemScene
Product number
CS-2072
Product name
Cefoselis(sulfate)
Purity
99.41%
Packaging
5mg
Price
$60
Updated
2021/12/16
ApexBio Technology
Product number
B1906
Product name
CefoselisSulfate
Packaging
50mg
Price
$68
Updated
2021/12/16
ChemScene
Product number
CS-2072
Product name
Cefoselis(sulfate)
Purity
99.41%
Packaging
10mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC44038
Product name
Cefoselis sulfate
Packaging
5mg
Price
$105.5
Updated
2021/12/16
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Cefoselis sulfate Chemical Properties,Usage,Production

Description

Cefoselis is a new fourth-generation cephalosporin and was launched in Japan as a parenteral antibiotic for a variety of infections including Staphylococcus aureus (particularly the methicillin-resistant MRSA) and Pseudornonas aeruginosa. It can be prepared in 3 related ways, all using 2- pyrazolomethyl-3-cephem-4-carboxylic as the key intermediate. In preclinical studies, Cefolesis had better MIC50s than Ceftazidime against Streptococcus pneurnoniae or Staphflococcus aureus (methicillin-sensitive MSSA or resistant MRSA) and showed significant antibacterial activity against Citrobacter and Enterobacter.
Cefolesis is well tolerated in clinical studies, being eliminated mainly via glomerular filtration in humans.

Originator

Fujisawa (Japan)

Uses

antibiotic

Definition

ChEBI: Cefoselis sulfate is an azaheterocycle sulfate salt. It is functionally related to a member of cefoselis.

brand name

Wincef

Cefoselis sulfate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefoselis sulfate Suppliers

MedChemexpress LLC
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View Lastest Price from Cefoselis sulfate manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Cefoselis sulfate 122841-12-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-10-30
Hebei Mojin Biotechnology Co., Ltd
Product
Cefoselis sulfate 122841-12-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-30
Shaanxi Dideu Medichem Co. Ltd
Product
Cefoselis sulfate 122841-12-7
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
300 MT
Release date
2020-05-23

122841-12-7, Cefoselis sulfateRelated Search:


  • CEFOSELIS SULFATE
  • FK 037
  • 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[2-(2-hydroxyethyl)-3-imino-1-pyrazolyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R-(6alpha,7beta(Z)))-7-(((2-Amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl)methyl)-8-oxo-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid sulfate
  • Winsef
  • (6R,7R,E)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydropyrazol-1-yl)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, sulfate
  • FK 037 Sulfate
  • Cefoselis sulfate USP/EP/BP
  • Cefoselis Sulfate (FK-037)
  • (6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-(2-hydroxyethyl)-3-imino-2,3-dihydro-1H-pyrazol-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfate (1:1) (salt)
  • 122841-12-7
  • C19H22N8O6S2H2O4SC
  • C19H22N8O6S2H2O4SC19H24N8O10S3
  • C19H22N8O6S2H2SO4
  • C19H24N8O10S3
  • Inhibitors
  • Cefoselis sulfate and its intermediates