Cefoselis

Product Name: Cefoselis
CAS No.: 122841-10-5
Chemical Name: Cefoselis
Synonyms: cefoselis;Cefoselis USP/EP/BP;(6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl]methyl]-8-oxo-, (6R,7R)-
CBNumber: CB1855261
Molecular Formula: C19H22N8O6S2
Formula Weight: 522.56
MOL File: 122841-10-5.mol

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Cefoselis Property

Density: 1.83±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 2.77±0.50(Predicted)
CAS DataBase Reference: 122841-10-5(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B1074
Product name: Cefoselis
Packaging: 5mg
Price: $153
Updated: 2021/12/16

ApexBio Technology

Product number: B1074
Product name: Cefoselis
Packaging: 10mg
Price: $246
Updated: 2021/12/16

ApexBio Technology

Product number: B1074
Product name: Cefoselis
Packaging: 50mg
Price: $633
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0005603
Product name: CEFOSELIS
Purity: 95.00%
Packaging: 1G
Price: $909.56
Updated: 2021/12/16

ApexBio Technology

Product number: B1074
Product name: Cefoselis
Packaging: 100mg
Price: $1012
Updated: 2021/12/16

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Cefoselis Chemical Properties,Usage,Production

Description

Cefotaxime (cefoselis, FK037) is a fourth-generation cephalosporin. Compared with the commonly used third-generation cephalosporins, it has a wider antibacterial spectrum and has enhanced effects on AmpCβ-lactamase-producing Enterobacteriaceae bacteria.

Uses

Cefoselis can inhibit the cross-linking of mucinous peptide chains in the process of cell wall synthesis, so that bacteria cannot form a complete cell wall; eventually induce sensitive bacteria to form filaments, so that the bacteria eventually dissolve and die.

Biological Activity

cefoselis is a widely used antibiotic of β-lactam [1].cefoselis has a large antibacterial spectrum against gram positive bacterium. it is a 4th generation of cephalosporin. cefoselis has some side effects, such as inducing seizures and convulsion in elder and renal failure patients. through testing the dialysate and blood samples by hplc, it shows that cefoselis appears in the striatal dialysate samples does-dependently and disappears rapidly from the extracellular fluid. in renal failure rats, the elimination half-lives of cefoselis are prolonged. it may be one factor of the seizures caused by cefoselis. in addition, administration of cefoselis into the hippocampus causes highly increase of extracellular glutamate and slightly increase of gaba, suggesting that cefoselis induces seizures through blocking the gaba receptors [1].

target

β-lactam

References

[1] ohtaki k, matsubara k, fujimaru s, shimizu k, awaya t, suno m, chiba k, hayase n, shiono h. cefoselis, a beta-lactam antibiotic, easily penetrates the blood-brain barrier and causes seizure independently by glutamate release. j neural transm. 2004 dec;111(12):1523-35.

Cefoselis Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefoselis Suppliers

China 53 Europe 1 Germany 1 South Korea 1 United States 8 Global 64

Beijing HuaMeiHuLiBiological Chemical

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MedChemexpress LLC

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Sichuan Wei Keqi Biological Technology Co., Ltd.

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Shanghai HuanChuan Industry Co.,Ltd.

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Credit Asia Chemical Co., Ltd.

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Hubei Jusheng Technology Co.,Ltd

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BOC Sciences

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Shandong Xiya Chemical Co., Ltd.

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Amadis Chemical Company Limited

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Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
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View Lastest Price from Cefoselis manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Cefoselis 122841-10-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 300 MT
Release date: 2020-05-23

Career Henan Chemical Co

Product: Cefoselis 122841-10-5
Price: US $1.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 85.0-99.8%
Supply Ability: 20tons
Release date: 2020-01-08

122841-10-5, CefoselisRelated Search:

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cefoselis

(6r,7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[2,3-dihydro-2-(2-hydroxyethyl)-3-imino-1H-pyrazol-1-yl]methyl]-8-oxo-, (6R,7R)-

Cefoselis USP/EP/BP

122841-10-5

C19H22N8O6S2