Ethyl tetrahydro-2-furoate
- Product Name
- Ethyl tetrahydro-2-furoate
- CAS No.
- 16874-34-3
- Chemical Name
- Ethyl tetrahydro-2-furoate
- Synonyms
- Ethyl tetrahydro-2-f;Ethyl tetrahydrofuroate;ETHYL TETRAHYDRO-2-FUROATE;Ethyl Tetrahydro-2-fuorate;ethyl oxolane-2-carboxylate;2-ethyl-2-oxolanecarboxylate;Ethyl tetrahydrofuran-2-carboxylate;2-Furancarboxylic acid,tetrahydro-, ethyl ester
- CBNumber
- CB4263863
- Molecular Formula
- C7H12O3
- Formula Weight
- 144.17
- MOL File
- 16874-34-3.mol
Ethyl tetrahydro-2-furoate Property
- Boiling point:
- 76-78°C
- Density
- 1.069 g/cm3(Temp: 10 °C)
- vapor pressure
- 1.53-7.33hPa at 20-50℃
- storage temp.
- 2-8°C
- Appearance
- Colorless to light yellow Liquid
- LogP
- 1.11 at 22.8℃
- CAS DataBase Reference
- 16874-34-3(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Furancarboxylic acid, tetrahydro-, ethyl ester (16874-34-3)
Safety
- HS Code
- 2932190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E937275
- Product name
- EthylTetrahydro-2-fuorate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR913297
- Product name
- Ethyltetrahydro-2-furoate
- Purity
- 95%
- Packaging
- 1g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- 2H23-1-1B
- Product name
- Ethyltetrahydro-2-furoate
- Purity
- 95%
- Packaging
- 1g
- Price
- $232
- Updated
- 2021/12/16
- Product number
- OR913297
- Product name
- Ethyltetrahydro-2-furoate
- Purity
- 95%
- Packaging
- 5g
- Price
- $555
- Updated
- 2021/12/16
- Product number
- 2H23-1-1B
- Product name
- Ethyltetrahydro-2-furoate
- Purity
- 95%
- Packaging
- 5G
- Price
- $888
- Updated
- 2021/12/16
Ethyl tetrahydro-2-furoate Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liqui
Uses
Ethyl Tetrahydro-2-fuorate is a useful reactant for the synthesis of spiro/fused dihydrofurans and dihydropyrans.
Synthesis
16874-33-2
16874-34-3
General procedure for the synthesis of ethyl tetrahydrofuran-2-carboxylate from 2-tetrahydrofurancarboxylic acid: to a solution of 2-tetrahydrofurancarboxylic acid (20 g, 172.2356 mmol) in anhydrous ethanol (100 mL) was slowly added concentrated sulfuric acid (0.46 mL) as a catalyst. The reaction mixture was placed under reflux conditions and stirred for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature. Subsequently, the reaction mixture was diluted by adding water (100 mL) and extracted with ether (3 x 100 mL). The organic phases were combined and washed sequentially with saturated aqueous sodium bicarbonate solution (2 x 50 mL) and saturated aqueous sodium chloride solution (100 mL). The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford ethyl tetrahydrofuran-2-carboxylate (22.5964 g, 91% yield) as a colorless liquid. The product was detected by LRMS at m/z 145 (M + H)+. 1H NMR (CDCl3, 300 MHz) data were as follows: δ 4.38 (1H, dd, J = 4.9, 8.1 Hz), 4.14 (2H, q, J = 7.2 Hz), 3.99-3.92 (1H, m), 3.88-3.81 (1H, m), 2.24- 2.12 (1H, m), 2.00-1.79 (3H, m), 1.22 (3H, t, J = 7.2 Hz).
References
[1] Patent: US2005/187266, 2005, A1
Ethyl tetrahydro-2-furoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl tetrahydro-2-furoate manufacturers
- Product
- Ethyl tetrahydro-2-furoate 16874-34-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99% HPLC
- Supply Ability
- 1000kg
- Release date
- 2023-07-05
- Product
- (S)-ethyl tetrahydrofuran-2-carboxylate 16874-34-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- (S)-ethyl tetrahydrofuran-2-carboxylate 16874-34-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09