1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
- Product Name
- 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
- CAS No.
- 332371-82-1
- Chemical Name
- 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
- Synonyms
- 1,7-BIS(4-HYDROXYPHENYL)HEPTA-4;1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one;1,7-bis(4-hydroxyphenyl)hepta-4E,6E-dien-3-one;(4E,6E)-1,7-Bis(4-hydroxyphenyl)-4,6-heptadien-3-one;4,6-Heptadien-3-one, 1,7-bis(4-hydroxyphenyl)-, (4E,6E)-
- CBNumber
- CB42654555
- Molecular Formula
- C19H18O3
- Formula Weight
- 294.34
- MOL File
- 332371-82-1.mol
N-Bromosuccinimide Price
- Product number
- CD32001632
- Product name
- 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $730
- Updated
- 2021/12/16
- Product number
- 332371821
- Product name
- 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
- Packaging
- 5mg
- Price
- $759.2
- Updated
- 2021/12/16
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one Chemical Properties,Usage,Production
Uses
1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 μM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2].
Definition
ChEBI: 1,7-bis(4-hydroxyphenyl)hepta-4E-6E-dien-3-one is a diarylheptanoid that is 4E-6E-dien-3-one substituted by 4-hydroxyphenyl group at positions 1 and 7. It has been isolated from the rhizomes of Curcuma kwangsiensis. It has a role as a plant metabolite. It is a diarylheptanoid, a member of phenols and an enone.
References
[1] Ali MS, et al. Six new diarylheptanoids from the seeds of Alpinia blepharocalyx. J Nat Prod. 2001 Mar;64(3):289-93. DOI:10.1021/np000496y
[2] Matsumoto T, et al. Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5178-81. DOI:10.1016/j.bmcl.2013.07.010
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one Preparation Products And Raw materials
Raw materials
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