ChemicalBook > CAS DataBase List > 2',7-DIHYDROXY-4'-METHOXYISOFLAVAN

2',7-DIHYDROXY-4'-METHOXYISOFLAVAN

Product Name
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
CAS No.
56701-24-7
Chemical Name
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
Synonyms
VESTITOL;DL-Vestitol;(±)-Vestitol;(+/-)-Vestitol;VESTITOL(RG)(PLEASE CALL);2',7-DIHYDROXY-4'-METHOXYISOFLAVAN;3-(2-Hydroxy-4-methoxyphenyl)-7-chromanol;3-(2-Hydroxy-4-methoxyphenyl)chroman-7-ol;3-(2-Hydroxy-4-Methoxyphenyl)-3,4-Dihydro-2H-Chromen-7-Ol;3-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
CBNumber
CB4268611
Molecular Formula
C16H16O4
Formula Weight
272.3
MOL File
56701-24-7.mol
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2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Property

Melting point:
172-179℃
Boiling point:
418.5±45.0 °C(Predicted)
Density 
1.282±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO: 2mg/mL, clear
form 
powder
pka
9.53±0.40(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3885
Product name
(±)-Vestitol
Purity
≥95% (HPLC)
Packaging
1 unit
Price
$399
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
PXT0001486
Product name
2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
Purity
95.00%
Packaging
5MG
Price
$505.38
Updated
2021/12/16
Arctom
Product number
AS013838
Product name
DL-Vestitol
Purity
≥98%
Packaging
5mg
Price
$282
Updated
2021/12/16
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2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Chemical Properties,Usage,Production

Uses

Vestitol is the compound isolated from leaves of Trifolium arvense[1].

Definition

ChEBI: Vestitol is a member of the class of hydroxyisoflavans that is isoflavan substituted by hydroxy groups at positions 7 and 2' and a methoxy group at position 4'. Isolated from Glycyrrhiza uralensis, it exhibits anti-inflammatory activity. It has a role as an anti-inflammatory agent, a plant metabolite and a phytoalexin. It is an aromatic ether, a member of hydroxyisoflavans and a methoxyisoflavan.

Biological Activity

Hydroxyisoflavan isolated from Cuban and Brazilian red propolis th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities.

(±)-Vestitol is a hydroxyisoflavan isolated from Cuban and Brazilian red propolis, licorice root and other sources th at exhibits potent anti-inflammatory, anti-viral, and antiparasitic activities. Apparently Vestitol inhibits release of the chemokines CXCL1/KC and CXCL2/MIP-2 from macrophages. Vestitol strongly inhibits Chikungunya virus infection. Vestitol exhibits anti-trypanosomal activity against T. brucei and T. congolense (EC50 3.86 and 4.36 μg/ml).

References

[1] John L. Ingham, et al. Notizen: Isoflavonoid Phytoalexins from Leaves of Trifolium arvense.

2',7-DIHYDROXY-4'-METHOXYISOFLAVAN Preparation Products And Raw materials

Raw materials

Preparation Products

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56701-24-7, 2',7-DIHYDROXY-4'-METHOXYISOFLAVANRelated Search:


  • VESTITOL
  • 2',7-DIHYDROXY-4'-METHOXYISOFLAVAN
  • 3-(2-Hydroxy-4-methoxyphenyl)-7-chromanol
  • 3-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
  • 3-(2-Hydroxy-4-methoxyphenyl)chroman-7-ol
  • 3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol
  • 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(2-hydroxy-4-methoxyphenyl)-
  • VESTITOL(RG)(PLEASE CALL)
  • (+/-)-Vestitol
  • 3-(2-Hydroxy-4-Methoxyphenyl)-3,4-Dihydro-2H-Chromen-7-Ol
  • DL-Vestitol
  • (±)-Vestitol
  • 56701-24-7
  • Iso-Flavones