2-Fluorophenylhydrazine
- Product Name
- 2-Fluorophenylhydrazine
- CAS No.
- 2368-80-1
- Chemical Name
- 2-Fluorophenylhydrazine
- Synonyms
- 2-Fluorophenylhrazine;2-FLUOROPHENYLHYDRAZINE;2-Fluoropherylhydrazine;o-Fluorophenylhydrazine;ASINEX-REAG BAS 05500094;1-fluoro-1-phenylhydrazine;1-(2-fluorophenyl)hydrazine;Hydrazine, (2-fluorophenyl)-
- CBNumber
- CB4268671
- Molecular Formula
- C6H7FN2
- Formula Weight
- 126.13
- MOL File
- 2368-80-1.mol
2-Fluorophenylhydrazine Property
- Melting point:
- 47°C
- Boiling point:
- 76-79°C/3mm
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- 4.73±0.10(Predicted)
- form
- solid
- color
- White to tan
- CAS DataBase Reference
- 2368-80-1(CAS DataBase Reference)
- EPA Substance Registry System
- Hydrazine, (2-fluorophenyl)- (2368-80-1)
Safety
- Hazard Codes
- Xi
- HS Code
- 2928009090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F594215
- Product name
- 2-Fluorophenylhydrazine
- Packaging
- 2.5g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- 047697
- Product name
- 2-Fluorophenylhydrazine
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
- Product number
- PC1759
- Product name
- 2-Fluorophenylhydrazine
- Packaging
- 1g
- Price
- $44
- Updated
- 2021/12/16
- Product number
- 3639-3-X0
- Product name
- 2-Fluorophenylhydrazine
- Packaging
- 1g
- Price
- $48
- Updated
- 2021/12/16
- Product number
- 047697
- Product name
- 2-Fluorophenylhydrazine
- Packaging
- 5g
- Price
- $105
- Updated
- 2021/12/16
2-Fluorophenylhydrazine Chemical Properties,Usage,Production
Synthesis
348-54-9
2368-80-1
General procedure for the synthesis of 2-fluorophenylhydrazine from o-fluoroaniline: 500 g of o-fluoroaniline and 1500 mL of 37% concentrated hydrochloric acid were added to a 10 L three-necked flask and cooled to 2 °C using an ice-salt bath. 857 g of 35% aqueous sodium nitrite solution was added slowly and dropwise under stirring, and the reaction temperature was controlled to be maintained at 0 to 5 °C for 1.5 hours. Subsequently, 730 mL of 37% concentrated hydrochloric acid, 730 mL of water, and 480 g of zinc powder were added to the reaction solution, and the reaction temperature was maintained at 18 °C until the reaction was complete and the reaction solution turned off-white. Then, 30% sodium hydroxide solution was slowly added to adjust the pH of the reaction solution to 10.5, and this process took about 2 hours, and then crystals were precipitated, and 295 g of 2-fluorophenylhydrazine crude product was obtained by filtration. Purification step: 295 g of 2-fluorophenylhydrazine crude was dissolved in 5900 mL of water, heated to 60 ℃ to make it completely dissolved, and added appropriate amount of activated carbon to decolorize for 20 minutes, and then thermo-filtered to obtain a colorless filtrate. The filtrate was allowed to stand for 5 hours and then continued to stand for 2 hours, and the precipitated crystal precipitate was collected by filtration to finally obtain 238g of purified 2-fluorophenylhydrazine.
References
[1] Journal of Medicinal Chemistry, 1991, vol. 34, # 9, p. 2892 - 2898
[2] Chemistry - An Asian Journal, 2015, vol. 10, # 8, p. 1618 - 1621
[3] Molecules, 2016, vol. 21, # 11,
[4] Patent: CN106518723, 2017, A. Location in patent: Paragraph 0037-0046
[5] Patent: CN106518714, 2017, A. Location in patent: Paragraph 0017 - 0023
2-Fluorophenylhydrazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Fluorophenylhydrazine manufacturers
- Product
- 2-Fluorophenylhydrazine 2368-80-1
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-24
- Product
- 2-Fluorophenylhydrazine 2368-80-1
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 343
- Release date
- 2019-09-01