Sterculic acid
- Product Name
- Sterculic acid
- CAS No.
- 738-87-4
- Chemical Name
- Sterculic acid
- Synonyms
- STERCULIC ACID;Sterculinic acid;9,10-Methylene-9-octadecenoicacid;2-Octyl-1-cyclopropene-1-octanoic acid;8-(2-Octacyclopropen-1-yl)octanoic acid;1-Cyclopropene-1-octanoic acid, 2-octyl-;8-(2-octylcyclopropen-1-yl)octanoic acid;8-(2-octylcyclopropen-1-yl)caprylic acid;8-(2 OCTYL 1-CYCLOPROPENYL) OCTANOIC ACID
- CBNumber
- CB4269502
- Molecular Formula
- C19H34O2
- Formula Weight
- 294.47
- MOL File
- 738-87-4.mol
Sterculic acid Property
- Melting point:
- 19 °C
- Boiling point:
- 418.7±24.0 °C(Predicted)
- Density
- 0.948±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Chloroform: soluble; Ether: soluble; Hexane: soluble; Methanol: soluble
- form
- A liquid
- pka
- 4.78±0.10(Predicted)
- color
- Colorless to light yellow
Safety
- Hazardous Substances Data
- 738-87-4(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- 26735
- Product name
- Sterculic Acid
- Packaging
- 25mg
- Price
- $396
- Updated
- 2024/03/01
- Product number
- API0008096
- Product name
- STERCULIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.87
- Updated
- 2021/12/16
- Product number
- 1154CA
- Product name
- Sterculicacid
- Packaging
- 25mg
- Price
- $638
- Updated
- 2021/12/16
Sterculic acid Chemical Properties,Usage,Production
Uses
Sterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM[1].
Definition
ChEBI: A long-chain, monounsaturated fatty acid composed of 9-octadecenoic acid having a 9,10-cyclopropenyl group.
in vivo
Sterculic acid has been proposed as a potential tool for the treatment of metabolic syndrome (MS) since it inhibits the activity of the stearoyl-CoA desaturase-1 (SCD1) in vivo[3].
IC 50
delta-9 desaturase: 0.9 μM (IC50)
References
[1] Lei Zhang, et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. J Biomol Screen. 2010 Feb;15(2):169-76. DOI:10.1177/1087057109356208
[2] Rafael Peláez, et al. Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases. Cells. 2020 Jan 7;9(1):140. DOI:10.3390/cells9010140
[3] Abril Ramírez-Higuera, et al. Preventive Action of Sterculic Oil on Metabolic Syndrome Development on a Fructose-Induced Rat Model. J Med Food. 2020 Mar;23(3):305-311. DOI:10.1089/jmf.2019.0177
Sterculic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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