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PHACLOFEN

Product Name
PHACLOFEN
CAS No.
114012-12-3
Chemical Name
PHACLOFEN
Synonyms
PHACLOFEN;PHACLOFEN GABA(B) RECEPTOR ANTA;3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;3-amino-2-(4-chlorophenyl)*propanephosphonic acid;(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-;Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-;Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci
CBNumber
CB4272748
Molecular Formula
C9H13ClNO3P
Formula Weight
249.63
MOL File
114012-12-3.mol
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PHACLOFEN Property

Melting point:
249-252 °C
Boiling point:
467.1±55.0 °C(Predicted)
Density 
1.432±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
0.1 M HCl: 13.3 mg/mL
form 
solid
pka
1.87±0.10(Predicted)
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P118
Product name
Phaclofen
Purity
solid
Packaging
5mg
Price
$132.6
Updated
2024/03/01
Sigma-Aldrich
Product number
P118
Product name
Phaclofen
Purity
solid
Packaging
25mg
Price
$833
Updated
2024/03/01
Sigma-Aldrich
Product number
P118
Product name
Phaclofen
Purity
solid
Packaging
100mg
Price
$2520
Updated
2024/03/01
Usbiological
Product number
256229
Product name
Phaclofen
Packaging
10mg
Price
$389
Updated
2021/12/16
ApexBio Technology
Product number
B6215
Product name
Phaclofen
Packaging
10mg
Price
$218
Updated
2021/12/16
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PHACLOFEN Chemical Properties,Usage,Production

Uses

Phaclofen is a selective GABAB?receptor antagonist.

General Description

Phaclofen is a phosphonic acid derivative of baclofen.

Biological Activity

Selective GABA B antagonist. Phosphono analog of GABA B agonist baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid ).

Biochem/physiol Actions

Phaclofen plays a vital role in identifying the physiological importance of central and peripheral bicuculline-insensitive receptors with which GABA and (?) baclofen interact. Phaclofen acts as a GABAB receptor antagonist. Phaclofen has an ability to reversibly block the late, bicuculline resistant, K+ dependent inhibitory postsynaptic potential (IPSP) logged in projection cells of the cat and rat dorsal lateral geniculate nucleus and in rat hippocampal CA1 pyramidal neurons.

PHACLOFEN Preparation Products And Raw materials

Raw materials

Preparation Products

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PHACLOFEN Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
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China
ProdList
15839
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Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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57
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
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China
ProdList
1637
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Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
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80
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
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58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
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MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
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Hubei Qifei Pharmaceutical Chemical Co., Ltd
Tel
027-027-59322506 18071128681
Fax
027-59322506
Email
1438082200@qq.com
Country
China
ProdList
9976
Advantage
58

114012-12-3, PHACLOFENRelated Search:


  • 3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID
  • PHACLOFEN
  • (RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID
  • 3-amino-2-(4-chlorophenyl)*propanephosphonic acid
  • PHACLOFEN GABA(B) RECEPTOR ANTA
  • Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-
  • Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-
  • Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci
  • 114012-12-3
  • C9H13CINO3P
  • C9H13ClNO3P
  • GABA/Glycine receptor