PHACLOFEN
- Product Name
- PHACLOFEN
- CAS No.
- 114012-12-3
- Chemical Name
- PHACLOFEN
- Synonyms
- PHACLOFEN;PHACLOFEN GABA(B) RECEPTOR ANTA;3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;3-amino-2-(4-chlorophenyl)*propanephosphonic acid;(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLPHOSPHONIC ACID;Phosphonic acid, (3-amino-2-(4-chlorophenyl)propyl)-;Phosphonic acid, P-[3-amino-2-(4-chlorophenyl)propyl]-;Phaclofen,(RS)-3-Amino-2-(4-chlorophenyl)propylphosphonicaci
- CBNumber
- CB4272748
- Molecular Formula
- C9H13ClNO3P
- Formula Weight
- 249.63
- MOL File
- 114012-12-3.mol
PHACLOFEN Property
- Melting point:
- 249-252 °C
- Boiling point:
- 467.1±55.0 °C(Predicted)
- Density
- 1.432±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- 0.1 M HCl: 13.3 mg/mL
- form
- solid
- pka
- 1.87±0.10(Predicted)
- color
- white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P118
- Product name
- Phaclofen
- Purity
- solid
- Packaging
- 5mg
- Price
- $132.6
- Updated
- 2024/03/01
- Product number
- P118
- Product name
- Phaclofen
- Purity
- solid
- Packaging
- 25mg
- Price
- $833
- Updated
- 2024/03/01
- Product number
- P118
- Product name
- Phaclofen
- Purity
- solid
- Packaging
- 100mg
- Price
- $2520
- Updated
- 2024/03/01
- Product number
- 256229
- Product name
- Phaclofen
- Packaging
- 10mg
- Price
- $389
- Updated
- 2021/12/16
- Product number
- B6215
- Product name
- Phaclofen
- Packaging
- 10mg
- Price
- $218
- Updated
- 2021/12/16
PHACLOFEN Chemical Properties,Usage,Production
Uses
Phaclofen is a selective GABAB?receptor antagonist.
General Description
Phaclofen is a phosphonic acid derivative of baclofen.
Biological Activity
Selective GABA B antagonist. Phosphono analog of GABA B agonist baclofen ((RS)-4-Amino-3-(4-chlorophenyl)butanoic acid ).
Biochem/physiol Actions
Phaclofen plays a vital role in identifying the physiological importance of central and peripheral bicuculline-insensitive receptors with which GABA and (?) baclofen interact. Phaclofen acts as a GABAB receptor antagonist. Phaclofen has an ability to reversibly block the late, bicuculline resistant, K+ dependent inhibitory postsynaptic potential (IPSP) logged in projection cells of the cat and rat dorsal lateral geniculate nucleus and in rat hippocampal CA1 pyramidal neurons.
PHACLOFEN Preparation Products And Raw materials
Raw materials
Preparation Products
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