ChemicalBook > CAS DataBase List > 2,2,5-Trimethyl-1,3-dioxane-4,6-dione

2,2,5-Trimethyl-1,3-dioxane-4,6-dione

Product Name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
CAS No.
3709-18-0
Chemical Name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Synonyms
CHEMPACIFIC 41980;METHYL MELDRUM'S ACID;CYCL-ISOPROPYLIDENE METHYLMALONATE;2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE;1,3-DIOXANE-4,6-DIONE, 2,2,5-TRIMETHYL;2,2,5-Trimethyl-1,3-dioxane-4,6-dione C;2,2,5-Trimethyl-1,3-Dioxane-4,6-Dione 98%;(2S)-2-amino-3-(3-thiophenyl)propanoic acid;METHYLMALONIC ACID CYCLIC ISOPROPYLIDENE ESTER;Methyl MeldruM's acid,2,2,5-TriMethyl-1,3-dioxane-4,6-dione
CBNumber
CB4277839
Molecular Formula
C7H10O4
Formula Weight
158.15
MOL File
3709-18-0.mol
More
Less

2,2,5-Trimethyl-1,3-dioxane-4,6-dione Property

Melting point:
111-114 °C(lit.)
Boiling point:
203.22°C (rough estimate)
Density 
1.1229 (rough estimate)
refractive index 
1.4610 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Methanol
form 
Solid
pka
13.14±0.40(Predicted)
color 
White to Off-White
BRN 
124044
InChIKey
KJMCAXYHYPDRAV-UHFFFAOYSA-N
CAS DataBase Reference
3709-18-0(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
23-24/25
WGK Germany 
3
10-21
HS Code 
29171990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
210153
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Purity
97%
Packaging
25g
Price
$268
Updated
2024/03/01
TRC
Product number
T796215
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Packaging
25g
Price
$85
Updated
2021/12/16
AK Scientific
Product number
J94384
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Packaging
5g
Price
$35
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019174
Product name
2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE
Purity
95.00%
Packaging
25G
Price
$1229.73
Updated
2021/12/16
Alichem
Product number
3709180
Product name
2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Packaging
100g
Price
$277.2
Updated
2021/12/16
More
Less

2,2,5-Trimethyl-1,3-dioxane-4,6-dione Chemical Properties,Usage,Production

Chemical Properties

White to slightly pink crystalline powder

Uses

2,2,5-Trimethyl-1,3-dioxane-4,6-dione is used as a reagent in the synthesis of 3'',4''-bis-difluoromethoxycinnamoylanthranilate (FT061) which is an orally-active antifibrotic agent that reduces albuminuria in rat models of progressive diabetic nephropathy.

Uses

2,2,5-Trimethyl-1,3-dioxane-4,6-dione was used for trapping the adduct formed during the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates.

General Description

X-ray irradiated single crystals of 2,2,5-trimethyl-1,3-dioxane-4,6-dione have been investigated by electron spin resonance (ESR), electron nuclear double resonance (ENDOR) and electron-electron double resonance (ELDOR) spectra.

2,2,5-Trimethyl-1,3-dioxane-4,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2,2,5-Trimethyl-1,3-dioxane-4,6-dione Suppliers

MedicalChem(Yancheng)Manuf.Co.,Ltd
Tel
+86-515-84383180
Fax
+86-515-84383182
Email
sales@medicalchem.com
Country
China
ProdList
80
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9458
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Suzhou Sino Rare Chemical Co., Ltd.
Tel
0512-62857507
Fax
+86-512-62857507
Email
sales@sinorarechem.com
Country
China
ProdList
965
Advantage
58
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
More
Less

View Lastest Price from 2,2,5-Trimethyl-1,3-dioxane-4,6-dione manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,2,5-Trimethyl-1,3-dioxane-4,6-dione 3709-18-0
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-19
Career Henan Chemical Co
Product
2,2,5-Trimethyl-1,3-dioxane-4,6-dione 3709-18-0
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-23

3709-18-0, 2,2,5-Trimethyl-1,3-dioxane-4,6-dioneRelated Search:


  • CHEMPACIFIC 41980
  • CYCL-ISOPROPYLIDENE METHYLMALONATE
  • METHYLMALONIC ACID CYCLIC ISOPROPYLIDENE ESTER
  • METHYL MELDRUM'S ACID
  • 2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE
  • 1,3-DIOXANE-4,6-DIONE, 2,2,5-TRIMETHYL
  • 2-METHYLCYCLOPROPANECARBOXYLIC ACID, 98% , MIXTURE OF CIS AND TRANS
  • 2,2,5-Trimethyl-1,3-Dioxane-4,6-Dione 98%
  • 2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE(METHYL MELDRUM''S ACID)
  • cycl-Isopropylidene methylmalonate, Methyl Meldrum’s acid
  • Methyl MeldruM's acid,2,2,5-TriMethyl-1,3-dioxane-4,6-dione
  • cycl-Isopropylidene methylmalonate, Methyl Meldrums acid, Methylmalonic acid cyclic isopropylidene ester
  • Methyl Meldrums acid, Methylmalonic acid cyclic isopropylidene ester
  • (2S)-2-amino-3-(3-thiophenyl)propanoic acid
  • 2,2,5-Trimethyl-1,3-dioxane-4,6-dione C
  • 3709-18-0
  • C7H10O4
  • Building Blocks
  • Carbonyl Compounds
  • Organic Building Blocks
  • Lactones