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MOLLUGIN

Product Name
MOLLUGIN
CAS No.
55481-88-4
Chemical Name
MOLLUGIN
Synonyms
MOLLUGIN;Rubimaillin;Mollugin-RM;MOLLUGIN(SH);Mollugin/rubiMaillin;RUBIMAILLIN; MOLLUGIN;6-hydroxy-2, 2-dimethyl-, methylester;Mollugin, 98%, from Rubia cordifolia L.;2H-Naphtho[1,2-b]pyran-5-carboxylic acid;Methyl 6-hydroxy-2,2-dimethylbenzo[h]chromene-5-carboxylate
CBNumber
CB4279530
Molecular Formula
C17H16O4
Formula Weight
284.31
MOL File
55481-88-4.mol
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MOLLUGIN Property

Melting point:
132～134℃
Boiling point:
453.2±45.0 °C(Predicted)
Density 
1.239±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
8.40±0.40(Predicted)
color 
Yellow to Green
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Safety

Safety Statements 
24/25
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00431
Product name
Mollugin
Purity
≥98% (HPLC)
Packaging
1MG
Price
$137
Updated
2023/06/20
Sigma-Aldrich
Product number
SMB00431
Product name
Mollugin
Purity
≥98% (HPLC)
Packaging
5MG
Price
$340
Updated
2023/06/20
Sigma-Aldrich
Product number
PHL80499
Product name
Mollugin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$435
Updated
2023/06/20
TCI Chemical
Product number
M3091
Product name
Mollugin
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$85
Updated
2024/03/01
TCI Chemical
Product number
M3091
Product name
Mollugin
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$253
Updated
2024/03/01
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MOLLUGIN Chemical Properties,Usage,Production

Uses

Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.

Definition

ChEBI: Rubimaillin is a benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. It has a role as a plant metabolite, an acyl-CoA:cholesterol acyltransferase 2 inhibitor, a NF-kappaB inhibitor, an antineoplastic agent, an apoptosis inducer, a neuroprotective agent and an anti-inflammatory agent. It is a benzochromene, a methyl ester and a member of phenols.

Biological Activity

Mollugin displays inhibitory activity in arachidonic acid- and collagen-induced platelet aggregation. Mollugin has been reported to inhibit cancer cell proliferation, and has other biological activities including anti-inflammatory and apoptotic effects.

MOLLUGIN Preparation Products And Raw materials

Raw materials

Preparation Products

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MOLLUGIN Suppliers

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View Lastest Price from MOLLUGIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Mollugin 55481-88-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-08
Shanghai Standard Technology Co., Ltd.
Product
Mollugin 55481-88-4
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-10-08
Career Henan Chemical Co
Product
MOLLUGIN 55481-88-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-05-25

55481-88-4, MOLLUGINRelated Search:

ASARININ Paederosidic acid Jujuboside B Astragaloside II Dihydromollugin 1-Hydroxy-2-naphthoic acid Trifluoromethoxybenzaldehyde2 1-ALLYLOXYNAPHTHALENE 1,4-Dihydroxy-2-naphthoic acid METHYL 5-METHOXYSALICYLATE MOLLUGIN 4-METHOXY-1-NAPHTHOL 5-Methoxysalicylic acid 3-ALLYLOXY-BENZOIC ACID 3-(ALLYLOXY)BENZALDEHYDE METHYL 1-HYDROXY-2-NAPHTHOATE 1-(Allyloxy)-4-(hydroxymethyl)benzene 5-ETHOXYSALICYLIC ACID

  • Rubimaillin
  • 2H-Naphtho[1,2-b]pyran-5-carboxylic acid
  • 6-hydroxy-2, 2-dimethyl-, methylester
  • 2,2-Dimethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
  • 6-Hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester
  • MOLLUGIN
  • Methyl 6-hydroxy-2,2-dimethylbenzo[h]chromene-5-carboxylate
  • RUBIMAILLIN; MOLLUGIN
  • Mollugin/rubiMaillin
  • 2-DiMethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid Methyl ester
  • MOLLUGIN(SH)
  • Mollugin, 98%, from Rubia cordifolia L.
  • 2H-Naphtho[1,2-b]pyran-5-carboxylic acid, 6-hydroxy-2,2-dimethyl-, methyl ester
  • 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylic Acid Methyl Ester
  • Methyl 6-Hydroxy-2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate
  • Mollugin-RM
  • 55481-88-4
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • reference substance