2,3-DIFLUORO-4-METHOXYBENZOIC ACID
- Product Name
- 2,3-DIFLUORO-4-METHOXYBENZOIC ACID
- CAS No.
- 773873-26-0
- Chemical Name
- 2,3-DIFLUORO-4-METHOXYBENZOIC ACID
- Synonyms
- 2,3-Difluoro-6-methoxybenzoic acid;2,3-Difluoro-4-methoxylbenzoic acid;Benzoic acid, 2,3-difluoro-6-methoxy-
- CBNumber
- CB4297305
- Molecular Formula
- C8H6F2O3
- Formula Weight
- 188.13
- MOL File
- 773873-26-0.mol
2,3-DIFLUORO-4-METHOXYBENZOIC ACID Property
- Melting point:
- 126-129°C
- Boiling point:
- 275.0±35.0 °C(Predicted)
- Density
- 1.399±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.82±0.10(Predicted)
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D452060
- Product name
- 2,3-Difluoro-6-methoxybenzoicAcid
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FD67545
- Product name
- 2,3-Difluoro-6-methoxybenzoic acid
- Packaging
- 10g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- FD67545
- Product name
- 2,3-Difluoro-6-methoxybenzoic acid
- Packaging
- 5G
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 116758
- Product name
- 2,3-Difluoro-6-methoxybenzoicacid
- Packaging
- 5g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- X2810
- Product name
- 2,3-Difluoro-6-methoxybenzoicacid
- Packaging
- 5g
- Price
- $189
- Updated
- 2021/12/16
2,3-DIFLUORO-4-METHOXYBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
187543-87-9
773873-26-0
General procedure for the synthesis of 2,3-difluoro-6-methoxybenzoic acid from 2,3-difluoro-6-methoxybenzaldehyde: 1. Preparation of reaction system: 2,3-difluoro-6-methoxybenzaldehyde (0.5 g, 2.91 mmol) was suspended in potassium hydroxide solution (3 g KOH dissolved in 20 ml of water). 2. Oxidizing reaction: hydrogen peroxide solution (27.5% w/w, 4 ml) was added to the above suspension, followed by heating the reaction at 70°C for 2 hours. 3. Acidification: after completion of the reaction, the reaction mixture was acidified to pH 2 with concentrated hydrochloric acid. 4. Extractive separation: the acidified reaction mixture was washed with ethyl acetate. 5. Drying and concentration: the organic phases were combined, dried with anhydrous magnesium sulfate, filtered and the solvent was evaporated in vacuum. 6. Purification: Further purification by azeotropy with toluene afforded 2,3-difluoro-6-methoxybenzoic acid as a white solid (500 mg, 91% yield). Remarks: LC/MS analysis showed a retention time of 12.08 min and no molecular ion peak was observed.
References
[1] Patent: WO2006/77414, 2006, A1. Location in patent: Page/Page column 148
[2] Patent: CN105523921, 2016, A. Location in patent: Paragraph 0014; 0015; 0016
2,3-DIFLUORO-4-METHOXYBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2,3-DIFLUORO-4-METHOXYBENZOIC ACID Suppliers
- Tel
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- Fax
- --
- info@pschemicals.com
- Country
- The Netherlands
- ProdList
- 2724
- Advantage
- 58
- Tel
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- Fax
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- brunschwig@brunschwig.nl
- Country
- The Netherlands
- ProdList
- 4996
- Advantage
- 67
View Lastest Price from 2,3-DIFLUORO-4-METHOXYBENZOIC ACID manufacturers
- Product
- 2,3-DIFLUORO-4-METHOXYBENZOIC ACID 773873-26-0
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02