ChemicalBook > CAS DataBase List > Lenalidomide-d5

Lenalidomide-d5

Product Name
Lenalidomide-d5
CAS No.
1227162-34-6
Chemical Name
Lenalidomide-d5
Synonyms
CC-5013-d5;1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline-d5;3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione-d5
CBNumber
CB43070473
Molecular Formula
C13H8D5N3O3
Formula Weight
264.29142889
MOL File
1227162-34-6.mol
More
Less

Lenalidomide-d5 Property

storage temp. 
Store at -20°C
solubility 
DMSO: soluble,Methanol: soluble
form 
A solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
22370
Product name
Lenalidomide-d5
Purity
≥99% deuterated forms (d1-d5)
Packaging
500μg
Price
$201
Updated
2024/03/01
Cayman Chemical
Product number
22370
Product name
Lenalidomide-d5
Purity
≥99% deuterated forms (d1-d5)
Packaging
1mg
Price
$362
Updated
2024/03/01
AK Scientific
Product number
3538DG
Product name
3-(7-Amino-3-oxo-1H-isoindol-2-yl)-3,4,4,5,5-pentadeuteriopiperidine-2,6-dione
Packaging
1mg
Price
$500
Updated
2021/12/16
aablocks
Product number
AA009JKU
Product name
Lenalidomide-d5
Purity
≥99%deuteratedforms(d<sub>1</sub>-<wbr/>d<sub>5</sub>)
Packaging
1mg
Price
$422
Updated
2021/12/16
More
Less

Lenalidomide-d5 Chemical Properties,Usage,Production

Biological Activity

Lenalidomide-d5 is intended for use as an internal standard for the quantification of lenalidomide by GC- or LC-MS. Lenalidomide is related to thalidomide and, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.1 It also induces proliferation and enhances the functional capacity of T lymphocytes, amplifying co-stimulatory signaling pathways.2 Lenalidomide is effective in hematologic cancers, including lymphomas and myelomas.3,4

References

1.Kim, K., An, S., Cha, H.J., et al.Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cellsOncol.Lett.5(2)588-596(2013) 2.McDaniel, J.M., Pinilla-Ibarz, J., and Epling-Burnette, P.K.Molecular action of lenalidomide in lymphocytes and hematologic malignanciesAdv. Hematol.513702(2012) 3.Latif, T., Chauhan, N., Khan, R., et al.Thalidomide and its analogues in the treatment of multiple myelomaExp.Hermatol.Oncol.1(1)27(2012) 4.Merli, M., Ferrario, A., Basilico, C., et al.Novel agents in indolent lymphomasTher.Adv.Hematol.4(2)133-148(2013)

Lenalidomide-d5 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Lenalidomide-d5 Suppliers

Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
3044
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@qq.com
Country
China
ProdList
8705
Advantage
55
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9578
Advantage
60
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
info@synzest.com
Country
China
ProdList
9286
Advantage
58
Shanghai YuZn Pharm. Technology Co.,Ltd.
Tel
15921286451; 15921286451
Email
2010681527@qq.com
Country
China
ProdList
5095
Advantage
58
Shanghai isotope chemical co.,ltd
Tel
021-021-51600108 13062666369
Email
sales@chinaisotope.com
Country
China
ProdList
4271
Advantage
58
Cato Research Chemicals Inc.
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15726
Advantage
58
TLC Pharmaceutical Standards Ltd.
Tel
18012923235
Email
chinasales04@tlcstandards.com.cn
Country
China
ProdList
4918
Advantage
58
Guangzhou PI PI Biotech Inc
Tel
020-81716320 +86-13602409664
Fax
020-81716319
Email
Sales@pipitech.com
Country
China
ProdList
3633
Advantage
55