Lenalidomide-d5
- Product Name
- Lenalidomide-d5
- CAS No.
- 1227162-34-6
- Chemical Name
- Lenalidomide-d5
- Synonyms
- CC-5013-d5;1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline-d5;3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione-d5
- CBNumber
- CB43070473
- Molecular Formula
- C13H8D5N3O3
- Formula Weight
- 264.29142889
- MOL File
- 1227162-34-6.mol
Lenalidomide-d5 Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble,Methanol: soluble
- form
- A solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 22370
- Product name
- Lenalidomide-d5
- Purity
- ≥99% deuterated forms (d1-d5)
- Packaging
- 500μg
- Price
- $201
- Updated
- 2024/03/01
- Product number
- 22370
- Product name
- Lenalidomide-d5
- Purity
- ≥99% deuterated forms (d1-d5)
- Packaging
- 1mg
- Price
- $362
- Updated
- 2024/03/01
- Product number
- 3538DG
- Product name
- 3-(7-Amino-3-oxo-1H-isoindol-2-yl)-3,4,4,5,5-pentadeuteriopiperidine-2,6-dione
- Packaging
- 1mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- AA009JKU
- Product name
- Lenalidomide-d5
- Purity
- ≥99%deuteratedforms(d<sub>1</sub>-<wbr/>d<sub>5</sub>)
- Packaging
- 1mg
- Price
- $422
- Updated
- 2021/12/16
Lenalidomide-d5 Chemical Properties,Usage,Production
Biological Activity
Lenalidomide-d5 is intended for use as an internal standard for the quantification of lenalidomide by GC- or LC-MS. Lenalidomide is related to thalidomide and, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.1 It also induces proliferation and enhances the functional capacity of T lymphocytes, amplifying co-stimulatory signaling pathways.2 Lenalidomide is effective in hematologic cancers, including lymphomas and myelomas.3,4
References
1.Kim, K., An, S., Cha, H.J., et al.Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cellsOncol.Lett.5(2)588-596(2013) 2.McDaniel, J.M., Pinilla-Ibarz, J., and Epling-Burnette, P.K.Molecular action of lenalidomide in lymphocytes and hematologic malignanciesAdv. Hematol.513702(2012) 3.Latif, T., Chauhan, N., Khan, R., et al.Thalidomide and its analogues in the treatment of multiple myelomaExp.Hermatol.Oncol.1(1)27(2012) 4.Merli, M., Ferrario, A., Basilico, C., et al.Novel agents in indolent lymphomasTher.Adv.Hematol.4(2)133-148(2013)
Lenalidomide-d5 Preparation Products And Raw materials
Raw materials
Preparation Products
Lenalidomide-d5 Suppliers
- Tel
- --
- Fax
- --
- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81