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2-(BOC-AMINO)-3-METHYLPYRIDINE

Product Name
2-(BOC-AMINO)-3-METHYLPYRIDINE
CAS No.
138343-75-6
Chemical Name
2-(BOC-AMINO)-3-METHYLPYRIDINE
Synonyms
112777;BUTTPARK 92\50-22;2-BOC-Amino-3-picoline;N-Boc-3-methylpyridin-2-amine;2-(BOC-AMINO)-3-METHYLPYRIDINE;N-Boc-3-isopropylpyridin-2-amine;2-(N-Boc-Amino)-3-methylpyridine;2-(Boc-amino)-3-methylpyridine 97%;t-Butyl 3-methylpyridin-2-ylcarbamate;2-(N-BOC-AMINO)-3-METHYLPYRIDINE, 97%
CBNumber
CB4307903
Molecular Formula
C11H16N2O2
Formula Weight
208.26
MOL File
138343-75-6.mol
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2-(BOC-AMINO)-3-METHYLPYRIDINE Property

Melting point:
134-138 °C (lit.)
Boiling point:
268.5±28.0 °C(Predicted)
Density 
1.108±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
solid
pka
12.56±0.70(Predicted)
Appearance
White to off-white Solid
InChIKey
MJPLUXLNYQHWIU-UHFFFAOYSA-N
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36-43
Safety Statements 
26-36/37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
643920
Product name
2-(Boc-amino)-3-methylpyridine
Purity
97%
Packaging
25g
Price
$293
Updated
2023/06/20
TCI Chemical
Product number
B6201
Product name
tert-Butyl (3-Methylpyridin-2-yl)carbamate
Packaging
5G
Price
$25
Updated
2025/07/31
TCI Chemical
Product number
B6201
Product name
tert-Butyl (3-Methylpyridin-2-yl)carbamate
Packaging
25G
Price
$74
Updated
2025/07/31
TRC
Product number
B423328
Product name
tert-Butyl3-Methylpyridin-2-ylcarbamate
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
132690
Product name
tert-Butyl(3-methylpyridin-2-yl)carbamate
Purity
97%
Packaging
50g
Price
$360
Updated
2021/12/16
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2-(BOC-AMINO)-3-METHYLPYRIDINE Chemical Properties,Usage,Production

Synthesis Reference(s)

Tetrahedron, 64, p. 500, 2008 DOI: 10.1016/j.tet.2007.11.011

Synthesis

1603-40-3

24424-99-5

138343-75-6

General procedure for the synthesis of 2-(Boc-amino)-3-methylpyridine from 2-amino-3-methylpyridine and di-tert-butyl dicarbonate: di-tert-butyl dicarbonate (50.0 g) was dissolved in n-hexane (55 mL), heated to 58 °C with continuous stirring. Subsequently, a solution of ethyl acetate (20 mL) of 2-amino-3-methylpyridine (15.5 g) was added slowly and dropwise to this solution. The reaction mixture was heated and stirred at 58°C for 3 hours and then cooled to room temperature. The reaction mixture was diluted by addition of hexane (30 mL) and stirring was continued for 1.5 hours. The precipitated white solid precipitate was collected by filtration and dried to give 25.8 g of 2-(Boc-amino)-3-methylpyridine in 86% yield. Mass spectrometry (FAB) analysis showed m/z: 209 (M + H)+.

References

[1] Organic Process Research and Development, 2010, vol. 14, # 1, p. 168 - 173
[2] Patent: EP1764360, 2007, A1. Location in patent: Page/Page column 195
[3] Synthesis, 1996, # 7, p. 877 - 882
[4] Tetrahedron, 2008, vol. 64, # 3, p. 500 - 507
[5] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 21, p. 6582 - 6591

2-(BOC-AMINO)-3-METHYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(BOC-AMINO)-3-METHYLPYRIDINE Suppliers

Americas 1 Canada 1 China 111 Europe 2 France 1 Germany 1 India 4 Japan 1 Sweden 2 Switzerland 1 United Kingdom 1 United States 10 Global 136
Butt Park Ltd.
Tel
--
Fax
--
Email
113707.50@compuserve.com
Country
United Kingdom
ProdList
6078
Advantage
30
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View Lastest Price from 2-(BOC-AMINO)-3-METHYLPYRIDINE manufacturers

Dideu Industries Group Limited
Product
2-(BOC-AMINO)-3-METHYLPYRIDINE 138343-75-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-27
Career Henan Chemical Co
Product
2-BOC-Amino-3-picoline 138343-75-6
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

138343-75-6, 2-(BOC-AMINO)-3-METHYLPYRIDINERelated Search:

tert-butyl (3-formyl-4-hydroxyphenyl)carbamate tert-butyl (3-fluoropropyl)(2-hydroxyethyl)carbamate BOC-TRANS-4-AMINOCYCLOHEXANOL tert-butyl 1H-pyrrol-2-ylcarbamate Carbamic acid, 3-azabicyclo[3.1.0]hex-6-yl-, 1,1-dimethylethyl ester, N-(3-AMino[1,1'-biphenyl]-4-yl)-carbaMic Acid tert-Butyl Ester tert-butyl (2-bromo-3-fluorophenyl)carbamate tert-Butyl(3-formylbicyclo[1.1.1]pentan-1-yl)carbamate tert-butyl (3-(hydroxymethyl)bicyclo[1.1.1]pentan-1-yl)carbamate tert-butyl (2,2,3,3-tetramethylcyclopropyl)carbamate tert-butyl (3,5-dibromopyrazin-2-yl)carbamate 2-(tert-Butyloxycarbonyl-methylamino)-5-iodo-3-methylpyridine 2-(N-METHYL-N-BOC-AMINO)-3-METHYLPYRIDINE-5-BORONIC ACID PINACOL ESTER 2-N-Boc-amino-3-formylpyridine 2-(BOC-AMINO)-3-METHYLPYRIDINE (3-HYDROXYMETHYL-PYRIDIN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER 8-N-BOC-5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-METHYLAMINE 7-METHYL-3,4-DIHYDRO-2H-[1,8]NAPHTHYRIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

  • (3-METHYLPYRIDINE-2-YL)CARBAMIC ACID TERT-BUTYL ESTER
  • Carbamic acid, N-(3-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester
  • 2-tert-butoxycarbonylamino-3-methylpyridine
  • N-Boc-3-isopropylpyridin-2-amine
  • N-Boc-3-methylpyridin-2-amine
  • 2-BOC-Amino-3-picoline
  • t-Butyl 3-methylpyridin-2-ylcarbamate
  • tert-butyl N-(3-Methylpyridin-2-yl)carbaMate
  • tert-butyl (3-Methylpyridin-2-yl)carbaMate
  • Carbamic acid, (3-methyl-2-pyridinyl)-
  • 2-(Boc-amino)-3-methylpyridine 97%
  • BUTTPARK 92\50-22
  • 2-(BOC-AMINO)-3-METHYLPYRIDINE
  • 2-(N-BOC-AMINO)-3-METHYLPYRIDINE, 97%
  • Carbamic acid, (3-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI)
  • 112777
  • 2-(BOC-AMINO)-3-METHYLPYRIDINE ISO 9001：2015 REACH
  • tert-butyl N-(3-methyl-2-pyridyl)carbamate
  • 2-(N-Boc-Amino)-3-methylpyridine
  • 138343-75-6
  • C9 to C46
  • Building Blocks
  • Pyridines
  • Heterocyclic Building Blocks
  • N-BOC
  • pharmacetical
  • C9 to C46
  • Heterocyclic Building Blocks
  • Pyridines
  • Heterocyclic Compounds