ChemicalBook > CAS DataBase List > Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate

Product Name: Ethyl 2-chloronicotinate
CAS No.: 1452-94-4
Chemical Name: Ethyl 2-chloronicotinate
Synonyms: AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;Ethyl 2-chloronicotite;ETHYL 2-CHLORONICOTINATE;Ehtyl 2-chloronicotinate;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C
CBNumber: CB4312224
Molecular Formula: C8H8ClNO2
Formula Weight: 185.61
MOL File: 1452-94-4.mol

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Ethyl 2-chloronicotinate Property

Melting point:: 68 C
Boiling point:: 78°C (0.1 mmHg)
Density: 1.2445 g/cm3(Temp: 25 °C)
refractive index: 1.5210-1.5250
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -1.32±0.10(Predicted)
form: Liquid
color: Colorless to Light yellow to Light orange
InChI: InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3
InChIKey: PMIMPBYTPPRBGD-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=CC=C1C(OCC)=O
CAS DataBase Reference: 1452-94-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-60-37
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000445
Product name: Flunixin impurity C
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 55 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR2413
Product name: Flunixin Related Compound C
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50MG
Price: $574
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1274631
Product name: Flunixin impurity C
Packaging: 50mg
Price: $1490
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0000445
Product name: Flunixin impurity C
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000445
Price: $153
Updated: 2024/03/01

TCI Chemical

Product number: E0844
Product name: Ethyl 2-Chloronicotinate
Purity: >98.0%(GC)
Packaging: 25g
Price: $44
Updated: 2025/07/31

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Ethyl 2-chloronicotinate Chemical Properties,Usage,Production

Chemical Properties

Light yellow liquid

Uses

Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A

Synthesis

2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.

Ethyl 2-chloronicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ethyl 2-chloronicotinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Ethyl 2-chloronicotinate 1452-94-4
Price: US $0.00/KG
Min. Order: 200KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-11

Hebei Chuanghai Biotechnology Co., Ltd

Product: Ethyl 2-chloronicotinate 1452-94-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2025-03-07

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Ethyl 2-chloronicotinate 1452-94-4
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-05

1452-94-4, Ethyl 2-chloronicotinateRelated Search:

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ETHYL 2-CHLORONICOTINATE

ethyl 2-chloropyridine-3-carboxylate

2-CHLORONICOTINIC ACID ETHYL ESTER

2-Chloro-3-pyridinecarboxylic acid ethyl ester

2-Chloropyridine-3-carboxylic acid ethyl ester

Ethyl 2-chloronicoti

Ethyl 2-Chloro-3-pyridinecarboxylate

2-Chloronicotinic Acid Ethyl Ester Ethyl 2-Chloro-3-pyridinecarboxylate 2-Chloro-3-pyridinecarboxylic Acid Ethyl Ester

2-Chloronicotinate ethyl ester

Ethyl 2-chloropyridine-3-carboxylate, 2-Chloro-3-(ethoxycarbonyl)pyridine

Flunixin Related CoMpound C

Ethyl 2-chloronicotinate, 99%, 99%

Ethyl2-chloronicotinate,98%

AVAC-001

oronicotinate

Flunixin Meglumine Impurity 3（Flunixin Meglumine EP Impurity C）

Flunixin Meglumine EP Impurity C

Ethyl2-Chloronicotinate&gt

Ethyl 2-Chloropyridine-3-carboxylat

Flunixin EP Impurity C

Flunixin impurity CQ: What is Flunixin impurity C Q: What is the CAS Number of Flunixin impurity C Q: What is the storage condition of Flunixin impurity C Q: What are the applications of Flunixin impurity C

Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631)

Flunixin USP Related Compound C

ethy-2-chloroisonicoitate

Flunixin Meglumine Impurity C

Ehtyl 2-chloronicotinate

Ethyl 2-chloronicotinate, 98%min

Ethyl 2-chloronicotite

Flunixin Meglumine Impurity 6

1452-94-4

C8HBCINO2

pyridine series

Pyridines

Pharmaceutical Intermediates

Pyridine

Fluorobenzene