Uses
ChemicalBook > CAS DataBase List > Ethyl 4,6-dichloronicotinate

Ethyl 4,6-dichloronicotinate

Uses
Product Name
Ethyl 4,6-dichloronicotinate
CAS No.
40296-46-6
Chemical Name
Ethyl 4,6-dichloronicotinate
Synonyms
ethyl 4,6-dichloropyridine-3-carboxylate;Novobiocin Impurity 5;Ethyl 4,6-dichloronitinate;Ethy14,6-dichloronicotinate;ETHYL 4,6-DICHLORONICOTINATE;Ethyl 4,6-dicholoronicotinate;Ethyl 4,6-Dichloronicotinate >Ethyl 4,6-dichloronicotinate ,97%;ethyl 4,6-dichloronicotinate (en);2,4-Dichloro-5-carbethoxypyridine
CBNumber
CB6102429
Molecular Formula
C8H7Cl2NO2
Formula Weight
220.05
MOL File
40296-46-6.mol
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Ethyl 4,6-dichloronicotinate Property

Melting point:
32-34°
Boiling point:
85°C/0.01mmHg(lit.)
Density 
1.367±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol.
pka
-1.24±0.10(Predicted)
form 
Liquid
color 
Yellow
InChI
InChI=1S/C8H7Cl2NO2/c1-2-13-8(12)5-4-11-7(10)3-6(5)9/h3-4H,2H2,1H3
InChIKey
AAUBVINEXCCXOK-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=CC(Cl)=C1C(OCC)=O
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1068
Product name
Ethyl 4,6-Dichloronicotinate
Purity
>98.0%(GC)
Packaging
1g
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
E1068
Product name
Ethyl 4,6-Dichloronicotinate
Purity
>98.0%(GC)
Packaging
5g
Price
$54
Updated
2024/03/01
Alfa Aesar
Product number
H63092
Product name
Ethyl 4,6-dichloronicotinate, 95%
Packaging
1g
Price
$63
Updated
2023/06/20
Alfa Aesar
Product number
H63092
Product name
Ethyl 4,6-dichloronicotinate, 95%
Packaging
5g
Price
$242
Updated
2023/06/20
Alfa Aesar
Product number
H63092
Product name
Ethyl 4,6-dichloronicotinate, 95%
Packaging
250mg
Price
$18.7
Updated
2021/12/16
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Ethyl 4,6-dichloronicotinate Chemical Properties,Usage,Production

Uses

Ethyl 4,6-Dichloronicotinate acts as a reactant in the preparation of (acylamino)aminonaphthyridinones as novobiocin analogs and Hsp90 inhibitors, their antitumor activities in human breast cancer cell lines, and the effects on aptoptosis and cell cycle advancement of selected compounds.

Chemical Properties

White solid

Uses

Ethyl 4,6-dichloronicotinate is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals, and dyestuffs. It is also used as a fine chemical intermediate. Ethyl-4,6-dichloronicotinate could be used as a starting material to synthesize 6-chlorothieno[3,2-c]pyridine-2-carbohydrazide-hydrazone subsidiaries[1].

References

[1] N. Rao, K. Prasad, M. Rao. “Synthesis and Antibacterial Evaluation of Hydrazone Derivatives Bearing 6-Chlorothieno[3,2-c]pyridine Moiety.” Asian Journal of Chemistry 1 1 (2019).

Ethyl 4,6-dichloronicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 4,6-dichloronicotinate Suppliers

Wuxi InterpiPharm, Inc.
Tel
510-83782303 13771177691
Fax
0510- 8378-9906
Email
sales@itppharm.com
Country
China
ProdList
110
Advantage
62
Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.
Tel
0519-0519-83812535
Email
sales@qinuochem.com
Country
China
ProdList
287
Advantage
60
Taizhou FRIEND Chemical Co., Ltd.
Tel
0523-86200082 15380713688
Fax
0523-86200991
Email
Austin@fredchem.cn
Country
China
ProdList
206
Advantage
55
Zhenjiang Carbochem Pharmatech Co.,LTD
Tel
0511-82018158 18136818960
Email
sales4@carbo-chem.com
Country
China
ProdList
292
Advantage
58
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
971
Advantage
62
Lanzhou Ulight Chemical Technology Co. Ltd
Tel
13919285024
Fax
13919285024
Email
863719335@qq.com
Country
China
ProdList
65
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from Ethyl 4,6-dichloronicotinate manufacturers

Suzhou Nordica Biopharma CO.,LTD
Product
Ethyl 4,6-dichloronicotinate 40296-46-6
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
0.99
Supply Ability
1 ton
Release date
2024-11-15
hebei hongtan Biotechnology Co., Ltd
Product
Ethyl 4,6-dichloronicotinate 40296-46-6
Price
US $20.00/g
Min. Order
10g
Purity
98%
Supply Ability
2000kg
Release date
2024-03-26
Hebei Yanxi Chemical Co., Ltd.
Product
Ethyl 4,6-dichloronicotinate 40296-46-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-22

40296-46-6, Ethyl 4,6-dichloronicotinateRelated Search:


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