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6-Chloronicotinic acid

Product Name
6-Chloronicotinic acid
CAS No.
5326-23-8
Chemical Name
6-Chloronicotinic acid
Synonyms
2-chloro-5-pyrdinecarboxylic acid;6-CHLOROPYRIDINE-3-CARBOXYLIC ACID;2-chloropyridine-5-carboxylic acid;6-ChL;6-Chloronicoti;TIMTEC-BB SBB004004;RARECHEM AL BO 0729;6 - chlorine niacin;6-Chloronicotinic ac;2-Chloroncotinic acid
CBNumber
CB4707499
Molecular Formula
C6H4ClNO2
Formula Weight
157.55
MOL File
5326-23-8.mol
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6-Chloronicotinic acid Property

Melting point:
190 °C (dec.)(lit.)
Boiling point:
241.15°C (rough estimate)
Density 
0.5
refractive index 
1.5870 (estimate)
Flash point:
192°C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
deionized water: soluble
form 
Crystalline Powder
pka
3.24±0.10(Predicted)
color 
Off-white to beige
Water Solubility 
Soluble in water (2 mg/ml at 20°C), ethanol, methanol, DMSO, and slightly soluble in chloroform.
Decomposition 
192 ºC
BRN 
115993
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
UAWMVMPAYRWUFX-UHFFFAOYSA-N
CAS DataBase Reference
5326-23-8(CAS DataBase Reference)
NIST Chemistry Reference
6-Chloronicotinic acid(5326-23-8)
EPA Substance Registry System
6-Chloronicotinic acid (5326-23-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25-37/39
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
156353
Product name
6-Chloropyridine-3-carboxylic acid
Purity
99%
Packaging
5g
Price
$45.7
Updated
2024/03/01
Sigma-Aldrich
Product number
156353
Product name
6-Chloropyridine-3-carboxylic acid
Purity
99%
Packaging
25g
Price
$57.4
Updated
2024/03/01
TCI Chemical
Product number
C1116
Product name
6-Chloronicotinic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$92
Updated
2024/03/01
TCI Chemical
Product number
C1116
Product name
6-Chloronicotinic Acid
Purity
>98.0%(T)
Packaging
100g
Price
$274
Updated
2024/03/01
Alfa Aesar
Product number
A15620
Product name
6-Chloronicotinic acid, 99%
Packaging
5g
Price
$35.65
Updated
2024/03/01
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6-Chloronicotinic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white to beige crystalline powder

Uses

6-Chloronicotinic acid is used as building block for different chemical synthesis. It is an intermediate for the synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAFV600E inhibitors, and novel DNA-gyrase B inhibitors.

Uses

6-Chloropyridine-3-carboxylic acid (6-chloronicotinic acid/6-CNA) has been used to study its photolytic and photocatalytic degradation. 6-CNA is a degradation product of neonicotinoid insecticides imidacloprid and acetamiprid and is known to appear in different environmental matrices. The product has been used as a media component during the isolation of 6-CNA degrading bacterial strain from imidacloprid-exposed soil samples.

Definition

ChEBI: 6-Chloronicotinic acid is a member of pyridines and an aromatic carboxylic acid.

General Description

6-Chloropyridine-3-carboxylic acid is a metabolite of the neonicotinoid pesticides, imidacloprid and acetamiprid and occurs in different environmental matrices.(3) It is widely used in agricultural crop protection, domestic insect control and environmental pest management.

Purification Methods

Purify it by recrystallisation from hot H2O and sublime it in a vacuum. [Pechmann & Welsch Chem Ber 17 2384 1884, Herz & Murty J Org Chem 26 122 1961, Beilstein 22/2 V 177.]

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6-Chloronicotinic acid Suppliers

Jiangyin Jufeng Biotechnology Co., Ltd
Tel
13906113265
Email
986329407@qq.com
Country
China
ProdList
44
Advantage
58
Shanghai Witofly Chemical Co. ,Ltd.
Tel
021-50630626 18964684208
Email
sales@witofly.com
Country
China
ProdList
1145
Advantage
55
Zaozhuang Benefit Chemical Co., Ltd.
Tel
18663238985
Fax
0531-69958783
Email
1948129184@qq.com
Country
China
ProdList
211
Advantage
60
NINGBO JL NEW MATERIAL CO.,LTD
Tel
0574-88552218 18969899212
Email
sales@jlbio-tech.cn
Country
China
ProdList
635
Advantage
58
Nanjing Dilu Pharmaceutical Co., Ltd
Tel
18014482516
Fax
QQ2853590738
Email
977144864@qq.com
Country
China
ProdList
379
Advantage
58
iangsu Runfeng Synthetic Technology Co., Ltd.
Tel
0513-66017678 18551497631
Email
507167383@qq.com
Country
China
ProdList
4194
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
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View Lastest Price from 6-Chloronicotinic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
6-Chloronicotinic acid 5326-23-8
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
Hebei Mojin Biotechnology Co., Ltd
Product
6-Chloronicotinic acid 5326-23-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-23
Hebei Guanlang Biotechnology Co,.LTD
Product
6-Chloronicotinic Acid 5326-23-8
Price
US $10.70/Kg/Bag
Min. Order
10g
Purity
99%
Supply Ability
10000kg
Release date
2021-08-16

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