ChemicalBook > CAS DataBase List > 5,6-Dichloronicotinic acid

5,6-Dichloronicotinic acid

Product Name
5,6-Dichloronicotinic acid
CAS No.
41667-95-2
Chemical Name
5,6-Dichloronicotinic acid
Synonyms
2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;Avatrhopal Impurity 45;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>
CBNumber
CB5261891
Molecular Formula
C6H3Cl2NO2
Formula Weight
192
MOL File
41667-95-2.mol
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5,6-Dichloronicotinic acid Property

Melting point:
164-168 °C(lit.)
Boiling point:
342.1±37.0 °C(Predicted)
Density 
1.612±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
2.87±0.10(Predicted)
form 
Powder
color 
White to beige to tan
BRN 
383740
InChI
InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
InChIKey
RNRLTTNKVLFZJS-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=C(Cl)C=C1C(O)=O
CAS DataBase Reference
41667-95-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
340219
Product name
5,6-Dichloropyridine-3-carboxylic acid
Purity
96%
Packaging
5g
Price
$26
Updated
2023/06/20
TCI Chemical
Product number
D2401
Product name
5,6-Dichloronicotinic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
D2401
Product name
5,6-Dichloronicotinic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$191
Updated
2024/03/01
Alfa Aesar
Product number
B25586
Product name
5,6-Dichloronicotinic acid, 98+%
Packaging
25g
Price
$209
Updated
2021/12/16
Alfa Aesar
Product number
B25586
Product name
5,6-Dichloronicotinic acid, 98+%
Packaging
5g
Price
$62.7
Updated
2021/12/16
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5,6-Dichloronicotinic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

5,6-Dichloronicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5,6-Dichloronicotinic acid Suppliers

Shandong Xuanshuo Pharmaceutical Technology Co. LTD
Tel
15269103900
Email
suchangzhou@shiningpharm.com
Country
China
ProdList
265
Advantage
58
Fuxin Crest Biotechnology Co. Ltd.
Tel
13062833949
Fax
QQ: 2073772974
Email
fred.wen@crcorporation.cn
Country
China
ProdList
853
Advantage
58
Wuxi Kehua Biological Technology Co., Ltd.
Tel
0510-0510-86838766
Email
2258830676@qq.com
Country
China
ProdList
4585
Advantage
58
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
6270
Advantage
58
Jinan Dexinjia Bio&Tech Co., Ltd
Tel
0531-82371986 15064117275
Fax
0531-82375893
Email
daisy@jndxj.com
Country
China
ProdList
1321
Advantage
58
ShenZhen H&D Pharmaceutical Technology Co., LTD
Tel
18672472998 18672472998
Email
2851922763@qq.com
Country
China
ProdList
7933
Advantage
58
Shandong Xuande Pharmaceutical Technology Co. LTD
Tel
18866895588
Fax
0531-82777287
Email
dingjiaying@shiningpharm.com
Country
China
ProdList
96
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
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View Lastest Price from 5,6-Dichloronicotinic acid manufacturers

Zison Pharmaceutical (Shandong) Co., Ltd.
Product
5,6-Dichloronicotinic acid 41667-95-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
≥98% by HPLC
Supply Ability
50kg/month
Release date
2023-01-05
Hebei Weibang Biotechnology Co., Ltd
Product
5,6-Dichloronicotinic acid 41667-95-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-26
Hebei Yanxi Chemical Co., Ltd.
Product
5,6-Dichloronicotinic acid 41667-95-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-13

41667-95-2, 5,6-Dichloronicotinic acidRelated Search:


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  • 41667-95-2
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  • Pyridines
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
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  • Chloropyridines
  • Halopyridines
  • Heterocycle-Pyridine series
  • Chloropyridines
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  • C5 to C6
  • C6 to C7
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  • Halogenated Heterocycles
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  • Pyridines
  • pharmacetical
  • Organic acids
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Intermediate