2-Mercaptonicotinic acid
- Product Name
- 2-Mercaptonicotinic acid
- CAS No.
- 38521-46-9
- Chemical Name
- 2-Mercaptonicotinic acid
- Synonyms
- 2-sulfanylpyridine-3-carboxylic acid;TIMTEC-BB SBB000123;2-Mercaptonicotinic;2-THIONICOTINIC ACID;Mercaptonicotinicaci;LABOTEST-BB LT01596005;2-MERCAPTOCOTINIC ACID;2-mercaptonitinic acid;2-Mercaptonicotinicaci;2-MERCAPTONICOTINIC ACID
- CBNumber
- CB4378840
- Molecular Formula
- C6H5NO2S
- Formula Weight
- 155.17
- MOL File
- 38521-46-9.mol
2-Mercaptonicotinic acid Property
- Melting point:
- 263-265 °C(lit.)
- Boiling point:
- 295.3±50.0 °C(Predicted)
- Density
- 1.357 (estimate)
- refractive index
- 1.5380 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 1.98±0.20(Predicted)
- form
- crystalline (fine)
- color
- yellow
- Sensitive
- Air Sensitive
- BRN
- 119029
- InChI
- InChI=1S/C6H5NO2S/c8-6(9)4-2-1-3-7-5(4)10/h1-3H,(H,7,10)(H,8,9)
- InChIKey
- WYKHFQKONWMWQM-UHFFFAOYSA-N
- SMILES
- C1(=S)NC=CC=C1C(O)=O
- CAS DataBase Reference
- 38521-46-9(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Mercaptonicotinic acid (38521-46-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 419702
- Product name
- 2-Mercaptopyridine-3-carboxylic acid
- Purity
- technical grade
- Packaging
- 25g
- Price
- $68.4
- Updated
- 2025/07/31
- Product number
- 419702
- Product name
- 2-Mercaptopyridine-3-carboxylic acid
- Purity
- technical grade
- Packaging
- 100g
- Price
- $169.38
- Updated
- 2025/07/31
- Product number
- M1213
- Product name
- 2-Mercaptonicotinic Acid
- Packaging
- 25g
- Price
- $58
- Updated
- 2025/07/31
- Product number
- M225440
- Product name
- 2-Mercaptonicotinic Acid
- Packaging
- 100g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- JK290761
- Product name
- 2-Mercaptonicotinic Acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $14
- Updated
- 2021/12/16
2-Mercaptonicotinic acid Chemical Properties,Usage,Production
Chemical Properties
yellow powder
Uses
2-Mercaptopyridine-3-carboxylic acid may be used for the synthesis of poly[[diaquabis([μ]2-4,4 ′-bipyridyl)iron(II)] bis{2-[(3-carboxypyridin-2-yl)disulfanyl]nicotinate}] and 2-(2-carboxyethylthio)nicotinic acid.
Reactions
2-Mercaptonicotinic acid is prone to decomposition and deterioration at high temperatures, it can undergo nucleophilic substitution reactions under the action of alkaline substances.
Hazard
2-Mercaptonicotinic acid is a flammable liquid and vapor, it causes severe skin burns and eye damage and may cause respiratory irritation.
Synthesis
2942-59-8
38521-46-9
The general procedure for the synthesis of 2-mercaptonicotinic acid from 2-chloronicotinic acid was as follows: a suspension of 2-chloronicotinic acid (790 mg, 5 mmol) and thiourea (457 mg, 6 mmol) was suspended in water (15 mL) and the reaction was carried out at reflux for 8 h at 90 °C. Upon completion of the reaction, the mixture was cooled to room temperature to obtain a pale yellow suspension. Subsequently, the pH was adjusted to about 8 with dilute hydrochloric acid and stirred for 10 minutes to precipitate 2-mercaptonicotinic acid as a pale yellow solid. The solid was separated by filtration and dried to give the target product 2-mercaptonicotinic acid (590 mg, 84% yield).
References
[1] Patent: CN103626693, 2016, B. Location in patent: Paragraph 0157-0159
[2] Roczniki Chemii, 1932, vol. 12, p. 493,495
[3] Chem. Zentralbl., 1932, vol. 103, # II, p. 3400
[4] Journal of the American Chemical Society, 1948, vol. 70, p. 3908,3910
2-Mercaptonicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Mercaptonicotinic acid manufacturers
- Product
- 2-Mercaptonicotinic acid 38521-46-9
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-02
- Product
- 2-Mercaptonicotinic acid 38521-46-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09
- Product
- 2-MERCAPTONICOTINIC ACID 38521-46-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 0.98
- Supply Ability
- 1000
- Release date
- 2024-07-19