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2-Mercaptonicotinic acid

Product Name
2-Mercaptonicotinic acid
CAS No.
38521-46-9
Chemical Name
2-Mercaptonicotinic acid
Synonyms
2-sulfanylpyridine-3-carboxylic acid;TIMTEC-BB SBB000123;2-Mercaptonicotinic;2-THIONICOTINIC ACID;Mercaptonicotinicaci;LABOTEST-BB LT01596005;2-MERCAPTOCOTINIC ACID;2-mercaptonitinic acid;2-Mercaptonicotinicaci;2-MERCAPTONICOTINIC ACID
CBNumber
CB4378840
Molecular Formula
C6H5NO2S
Formula Weight
155.17
MOL File
38521-46-9.mol
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2-Mercaptonicotinic acid Property

Melting point:
263-265 °C(lit.)
Boiling point:
295.3±50.0 °C(Predicted)
Density 
1.357 (estimate)
refractive index 
1.5380 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
pka
1.98±0.20(Predicted)
form 
crystalline (fine)
color 
yellow
Sensitive 
Air Sensitive
BRN 
119029
InChI
InChI=1S/C6H5NO2S/c8-6(9)4-2-1-3-7-5(4)10/h1-3H,(H,7,10)(H,8,9)
InChIKey
WYKHFQKONWMWQM-UHFFFAOYSA-N
SMILES
C1(=S)NC=CC=C1C(O)=O
CAS DataBase Reference
38521-46-9(CAS DataBase Reference)
EPA Substance Registry System
2-Mercaptonicotinic acid (38521-46-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
10-23
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
419702
Product name
2-Mercaptopyridine-3-carboxylic acid
Purity
technical grade
Packaging
25g
Price
$68.4
Updated
2025/07/31
Sigma-Aldrich
Product number
419702
Product name
2-Mercaptopyridine-3-carboxylic acid
Purity
technical grade
Packaging
100g
Price
$169.38
Updated
2025/07/31
TCI Chemical
Product number
M1213
Product name
2-Mercaptonicotinic Acid
Packaging
25g
Price
$58
Updated
2025/07/31
TRC
Product number
M225440
Product name
2-Mercaptonicotinic Acid
Packaging
100g
Price
$195
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK290761
Product name
2-Mercaptonicotinic Acid
Purity
98%
Packaging
5g
Price
$14
Updated
2021/12/16
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2-Mercaptonicotinic acid Chemical Properties,Usage,Production

Chemical Properties

yellow powder

Uses

2-Mercaptopyridine-3-carboxylic acid may be used for the synthesis of poly[[diaquabis([μ]2-4,4 ′-bipyridyl)iron(II)] bis{2-[(3-carboxypyridin-2-yl)disulfanyl]nicotinate}] and 2-(2-carboxyethylthio)nicotinic acid.

Synthesis

2942-59-8

38521-46-9

The general procedure for the synthesis of 2-mercaptonicotinic acid from 2-chloronicotinic acid was as follows: a suspension of 2-chloronicotinic acid (790 mg, 5 mmol) and thiourea (457 mg, 6 mmol) was suspended in water (15 mL) and the reaction was carried out at reflux for 8 h at 90 °C. Upon completion of the reaction, the mixture was cooled to room temperature to obtain a pale yellow suspension. Subsequently, the pH was adjusted to about 8 with dilute hydrochloric acid and stirred for 10 minutes to precipitate 2-mercaptonicotinic acid as a pale yellow solid. The solid was separated by filtration and dried to give the target product 2-mercaptonicotinic acid (590 mg, 84% yield).

References

[1] Patent: CN103626693, 2016, B. Location in patent: Paragraph 0157-0159
[2] Roczniki Chemii, 1932, vol. 12, p. 493,495
[3] Chem. Zentralbl., 1932, vol. 103, # II, p. 3400
[4] Journal of the American Chemical Society, 1948, vol. 70, p. 3908,3910

2-Mercaptonicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Mercaptonicotinic acid Suppliers

Shijiazhuang C-element Biotech Co.,Ltd
Tel
18033710157
Email
Lisa@C-elementBiotech.com
Country
China
ProdList
118
Advantage
58
Shijiazhuang Dowell Chemical Co., Ltd
Tel
0311-89805679 17692413312
Fax
0311-85262695
Email
sell@dowechem.com
Country
China
ProdList
61
Advantage
62
Shijiazhuang Coshine Chemical Co.,Ltd
Tel
18633820607 18633820607
Email
377964081@qq.com
Country
China
ProdList
93
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
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View Lastest Price from 2-Mercaptonicotinic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Mercaptonicotinic acid 38521-46-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-02
Henan Aochuang Chemical Co.,Ltd.
Product
2-Mercaptonicotinic acid 38521-46-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-09
Apeloa production Co.,Limited
Product
2-MERCAPTONICOTINIC ACID 38521-46-9
Price
US $1.00/g
Min. Order
1g
Purity
0.98
Supply Ability
1000
Release date
2024-07-19

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