6-Aminonicotinic acid
- Product Name
- 6-Aminonicotinic acid
- CAS No.
- 3167-49-5
- Chemical Name
- 6-Aminonicotinic acid
- Synonyms
- 3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
- CBNumber
- CB9449781
- Molecular Formula
- C6H6N2O2
- Formula Weight
- 138.12
- MOL File
- 3167-49-5.mol
6-Aminonicotinic acid Property
- Melting point:
- >300 °C (lit.)
- Boiling point:
- 253.51°C (rough estimate)
- Density
- 1.3471 (rough estimate)
- refractive index
- 1.5100 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2.86±0.10(Predicted)
- form
- Powder
- color
- White to beige
- Water Solubility
- ca 1.0 g/L (20 ºC)
- Merck
- 14,456
- BRN
- 115992
- InChI
- InChI=1S/C6H6N2O2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H2,7,8)(H,9,10)
- InChIKey
- ZCIFWRHIEBXBOY-UHFFFAOYSA-N
- SMILES
- C1=NC(N)=CC=C1C(O)=O
- CAS DataBase Reference
- 3167-49-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Nicotinic acid, 6-amino-(3167-49-5)
- EPA Substance Registry System
- 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-23/24/25
- Safety Statements
- 22-24/25-45-36/37/39-26
- WGK Germany
- 3
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 216879
- Product name
- 6-Aminopyridine-3-carboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $23.45
- Updated
- 2025/07/31
- Product number
- 216879
- Product name
- 6-Aminopyridine-3-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $24.9
- Updated
- 2023/06/20
- Product number
- A1486
- Product name
- 6-Aminonicotinic Acid
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $41
- Updated
- 2025/07/31
- Product number
- A1486
- Product name
- 6-Aminonicotinic Acid
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $122
- Updated
- 2025/07/31
- Product number
- A1379-13
- Product name
- 6-Aminonicotinic Acid
- Packaging
- 1g
- Price
- $355
- Updated
- 2021/12/16
6-Aminonicotinic acid Chemical Properties,Usage,Production
Chemical Properties
Light yellow Cryst
Uses
6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.
Uses
Antiproliferative
Application
6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).
Definition
ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.
General Description
Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.
Purification Methods
Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]
6-Aminonicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
6-Aminonicotinic acid Suppliers
- Tel
- 0311-88800819 13932107110
- Fax
- 86-0311-85111404
- sales@jztchem.com
- Country
- China
- ProdList
- 14
- Advantage
- 62
- Tel
- 0571-86828652 18857119830
- Fax
- 0571-83522824
- sales@chemtrue-bio.com
- Country
- China
- ProdList
- 252
- Advantage
- 58
- Tel
- 025-86819863 13913839793
- Fax
- 025-86819859
- sales@jinchemical.com
- Country
- China
- ProdList
- 25
- Advantage
- 58
- Tel
- 0311-89805679 17692413312
- Fax
- 0311-85262695
- sell@dowechem.com
- Country
- China
- ProdList
- 61
- Advantage
- 62
- Tel
- 18033710157
- Lisa@C-elementBiotech.com
- Country
- China
- ProdList
- 118
- Advantage
- 58
- Tel
- 0519-82619998
- Fax
- +86-519-82619997
- wu@sharechem.com
- Country
- China
- ProdList
- 29
- Advantage
- 54
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
View Lastest Price from 6-Aminonicotinic acid manufacturers
- Product
- 6-Aminonicotinic acid 3167-49-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-09-26
- Product
- 6-Aminonicotinic acid 3167-49-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 20tons
- Release date
- 2025-08-25
- Product
- 6-Aminonicotinic acid 3167-49-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09