6-Aminonicotinic acid
- Product Name
- 6-Aminonicotinic acid
- CAS No.
- 3167-49-5
- Chemical Name
- 6-Aminonicotinic acid
- Synonyms
- 3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
- CBNumber
- CB9449781
- Molecular Formula
- C6H6N2O2
- Formula Weight
- 138.12
- MOL File
- 3167-49-5.mol
6-Aminonicotinic acid Property
- Melting point:
- >300 °C (lit.)
- Boiling point:
- 253.51°C (rough estimate)
- Density
- 1.3471 (rough estimate)
- refractive index
- 1.5100 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 2.86±0.10(Predicted)
- form
- Powder
- color
- White to beige
- Water Solubility
- ca 1.0 g/L (20 ºC)
- Merck
- 14,456
- BRN
- 115992
- CAS DataBase Reference
- 3167-49-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Nicotinic acid, 6-amino-(3167-49-5)
- EPA Substance Registry System
- 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-23/24/25
- Safety Statements
- 22-24/25-45-36/37/39-26
- WGK Germany
- 3
- TSCA
- T
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 216879
- Product name
- 6-Aminopyridine-3-carboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $45.5
- Updated
- 2024/03/01
- Product number
- 216879
- Product name
- 6-Aminopyridine-3-carboxylic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $24.9
- Updated
- 2023/06/20
- Product number
- A1486
- Product name
- 6-Aminonicotinic Acid
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $41
- Updated
- 2024/03/01
- Product number
- A1486
- Product name
- 6-Aminonicotinic Acid
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $123
- Updated
- 2024/03/01
- Product number
- A11223
- Product name
- 6-Aminonicotinic acid, 98%
- Packaging
- 5g
- Price
- $99.65
- Updated
- 2024/03/01
6-Aminonicotinic acid Chemical Properties,Usage,Production
Chemical Properties
Light yellow Cryst
Uses
6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.
Uses
Antiproliferative
Application
6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).
Definition
ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.
General Description
Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.
Purification Methods
Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]
6-Aminonicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Aminonicotinic acid manufacturers
- Product
- 6-Aminonicotinic acid 3167-49-5
- Price
- US $32.00-1.40/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-07
- Product
- 6-AMinonicotinic acid 3167-49-5
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-02-23
- Product
- 6-Aminonicotinic acid 3167-49-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98.0% HPLC
- Supply Ability
- 1000 kg
- Release date
- 2023-05-23