ChemicalBook > CAS DataBase List > 6-Aminonicotinic acid

6-Aminonicotinic acid

Product Name
6-Aminonicotinic acid
CAS No.
3167-49-5
Chemical Name
6-Aminonicotinic acid
Synonyms
3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
CBNumber
CB9449781
Molecular Formula
C6H6N2O2
Formula Weight
138.12
MOL File
3167-49-5.mol
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6-Aminonicotinic acid Property

Melting point:
>300 °C (lit.)
Boiling point:
253.51°C (rough estimate)
Density 
1.3471 (rough estimate)
refractive index 
1.5100 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
2.86±0.10(Predicted)
form 
Powder
color 
White to beige
Water Solubility 
ca 1.0 g/L (20 ºC)
Merck 
14,456
BRN 
115992
CAS DataBase Reference
3167-49-5(CAS DataBase Reference)
NIST Chemistry Reference
Nicotinic acid, 6-amino-(3167-49-5)
EPA Substance Registry System
3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)
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Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-23/24/25
Safety Statements 
22-24/25-45-36/37/39-26
WGK Germany 
3
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
216879
Product name
6-Aminopyridine-3-carboxylic acid
Purity
97%
Packaging
5g
Price
$45.5
Updated
2024/03/01
Sigma-Aldrich
Product number
216879
Product name
6-Aminopyridine-3-carboxylic acid
Purity
97%
Packaging
1g
Price
$24.9
Updated
2023/06/20
TCI Chemical
Product number
A1486
Product name
6-Aminonicotinic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
A1486
Product name
6-Aminonicotinic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$123
Updated
2024/03/01
Alfa Aesar
Product number
A11223
Product name
6-Aminonicotinic acid, 98%
Packaging
5g
Price
$99.65
Updated
2024/03/01
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6-Aminonicotinic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.

Uses

Antiproliferative

Application

6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).

Definition

ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.

General Description

Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO2 at silver electrode has been reported.

Purification Methods

Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]

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View Lastest Price from 6-Aminonicotinic acid manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
6-Aminonicotinic Acid 3167-49-5
Price
US $10.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
10 ton
Release date
2024-08-21
Shaanxi Dideu Medichem Co. Ltd
Product
6-Aminonicotinic acid 3167-49-5
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-08
Henan Fengda Chemical Co., Ltd
Product
6-Aminonicotinic acid 3167-49-5
Price
US $32.00-1.40/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-07

3167-49-5, 6-Aminonicotinic acidRelated Search:


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