6-Aminonicotinic acid

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6-Aminonicotinic acid

Product Name: 6-Aminonicotinic acid
CAS No.: 3167-49-5
Chemical Name: 6-Aminonicotinic acid
Synonyms: 3-Pyridinecarboxylic acid, 6-amino-;6- aMinoacid;6-AMinonicotinic a;TIMTEC-BB SBB004186;RARECHEM AL BO 1167;6-Aminonicotinc Acid;6-AMINONICOTINIC ACID;Nicotinic acid, 6-amino-;2-Amino-5-carboxypyridine;6-Aminonicotinic acid 98%
CBNumber: CB9449781
Molecular Formula: C6H6N2O2
Formula Weight: 138.12
MOL File: 3167-49-5.mol

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6-Aminonicotinic acid Property

Melting point:: >300 °C (lit.)
Boiling point:: 253.51°C (rough estimate)
Density: 1.3471 (rough estimate)
refractive index: 1.5100 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 2.86±0.10(Predicted)
form: Powder
color: White to beige
Water Solubility: ca 1.0 g/L (20 ºC)
Merck: 14,456
BRN: 115992
CAS DataBase Reference: 3167-49-5(CAS DataBase Reference)
NIST Chemistry Reference: Nicotinic acid, 6-amino-(3167-49-5)
EPA Substance Registry System: 3-Pyridinecarboxylic acid, 6-amino- (3167-49-5)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38-23/24/25
Safety Statements: 22-24/25-45-36/37/39-26
WGK Germany: 3
TSCA: T
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 216879
Product name: 6-Aminopyridine-3-carboxylic acid
Purity: 97%
Packaging: 5g
Price: $45.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 216879
Product name: 6-Aminopyridine-3-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $24.9
Updated: 2023/06/20

TCI Chemical

Product number: A1486
Product name: 6-Aminonicotinic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $41
Updated: 2024/03/01

TCI Chemical

Product number: A1486
Product name: 6-Aminonicotinic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $123
Updated: 2024/03/01

Alfa Aesar

Product number: A11223
Product name: 6-Aminonicotinic acid, 98%
Packaging: 5g
Price: $99.65
Updated: 2024/03/01

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6-Aminonicotinic acid Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

6-Aminopyridine-3-carboxylic acid (6-Aminonicotinic acid) was used in the preparation of resin-bound 2-aminoazine.

Uses

Antiproliferative

Application

6-Aminonicotinic acid is an inhibitor of bacterial DNA gyrase and topoisomerase IV. It has been shown to inhibit the growth of a number of bacteria, including E. coli K-12, with potent inhibitory activity against these enzymes. It binds to the active sites on these enzymes and prevents them from working. The detection time for 6-aminonicotinic acid is about 3 hours after exposure. It has been shown to be more potent than other inhibitors of bacterial DNA gyrase and topoisomerase IV such as 2,4-diaminopyrimidine (2,4DAP).

Definition

ChEBI: An aminonicotinic acid in which the amino group is situated at position 6 of the pyridine ring.

General Description

Electrosynthesis of 6-aminopyridine-3-carboxylic acid (6-aminonicotinic acid) by electrochemical reduction of 2-amino-5-bromo and 2-amino-5-chloropyridine in the presence of CO₂at silver electrode has been reported.

Purification Methods

Crystallise the acid from aqueous acetic acid. Dry it in vacuo at 70o. [Beilstein 22 III/IV 6726.]

6-Aminonicotinic acid Preparation Products And Raw materials

Raw materials

2-Amino-5-methylpyridine Ammonium hydroxide Ethanol Acetic anhydride Benzene Hydrochloric acid Potassium permanganate Methanol Sodium hydroxide 4-Dimethylaminopyridine

Preparation Products

5,6-DICHLORONICOTINIC ACID ETHYL ESTER 2-Aminopyridine TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE

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View Lastest Price from 6-Aminonicotinic acid manufacturers

Henan Fengda Chemical Co., Ltd

Product: 6-Aminonicotinic acid 3167-49-5
Price: US $32.00-1.40/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-07

Hebei Duling International Trade Co. LTD

Product: 6-AMinonicotinic acid 3167-49-5
Price: US $60.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-02-23

Changzhou Guiding Bio-Tech. Co.,Ltd.

Product: 6-Aminonicotinic acid 3167-49-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98.0% HPLC
Supply Ability: 1000 kg
Release date: 2023-05-23

3167-49-5, 6-Aminonicotinic acidRelated Search:

Chromium picolinate 2,5-PYRIDINEDICARBOXYLIC ACID Aminopyrine Acetaminophen Quinolinic acid Glucosamine 2-Aminopyridine Sulfamic acid 3-Aminopyridine EC 2.6.1.2 4-Dimethylaminopyridine 2-chloro-5-cyanopyridine 2-Mercaptonicotinic acid 5,6-Dichloronicotinic acid 2-AMINONICOTINIC ACID,2-Aminonicotinic acid;2-Aminopyridine-3-carboxylic acid,2-Aminonicotinic acid, 98+%,2-Aminonicotinic acid 98% 4-AMINONICOTINIC ACID,4-AMINONICOTINIC ACID, 98.5%,4-Aminonicotinic acid 99% 5-Aminonicotinic acid ,98%,5-AMINONICOTINIC ACID Methyl 6-aminonicotinate

3-Pyridinecarboxylic acid, 6-amino-

6-amino-3-pyridinecarboxylicaci

6-AMINONICOTINIC ACID

6-AMINOPYRIDINE-3-CARBOXYLIC ACID

2-AMINO-5-PYRIDINECARBOXYLIC ACID

2-AMINOPYRIDINE-5-CARBOXYLIC ACID

RARECHEM AL BO 1167

TIMTEC-BB SBB004186

2-Amino-5-carboxypyridine

6-Amino-3-pyridinecaboxylic acid

6-Aminonicotinic acid;6-Aminopyridine-3-carboxylic acid

6-AMINO-3-PYRIDINE CARBOXLIC ACID

6-Aminonicotinic acid, 98+%

2-Aminopyridine-5-carboxylic acid(6-Aminonicotinic acid)

6-Amino-3-pyridinecarboxylic Acid

6-Aminopyridine-3-carboxylic acid ,98%

6-Aminonicotinic acid 98%

3-Pyridinecarboxylicacid,6-amino-(9CI)

6-Aminonicotinc Acid

2-Aminopyridine-5-carboxylic acid, 6-Aminopyridine-3-carboxylic acid, 6-Amino-3-carboxypyridine

6-aMinopyridine-3-carbo×ylic acid

6-AMinonicotinic a

2-Aminopyridine-5-carboxylic acid, 6-Aminopyridine-3-carboxylic acid, 2-Amino-5-carboxypyridine

6- aMinoacid

Nicotinic acid, 6-amino-

2-AMINO-5-CARBOXAMIDE PYRIDINE

Nicotinic acid, 6-amino- (8CI)

6-Aminonicotinic Acid &gt

6-Aminonicotinic acid USP/EP/BP

6-Aminonicotinic acid?New

3167-49-5

3617-49-5

167-49-5

Building Blocks

CARBOXYLIC ACID

Heterocyclic Building Blocks

Pyridines

Aromatics

Chemical Amines

Heterocycles

Carboxylic Acids

AMINOACID

Amines

blocks

Carboxes

Pyridines

Pyridine

pyridine derivative

Pyridines, Pyrimidines, Purines and Pteredines

pharmacetical

Pyridine series

Carboxylic Acids

Organic acids