5,6-Dichloronicotinic acid

Product Name: 5,6-Dichloronicotinic acid
CAS No.: 41667-95-2
Chemical Name: 5,6-Dichloronicotinic acid
Synonyms: 2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;Avatrhopal Impurity 45;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>
CBNumber: CB5261891
Molecular Formula: C6H3Cl2NO2
Formula Weight: 192
MOL File: 41667-95-2.mol

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5,6-Dichloronicotinic acid Property

Melting point:: 164-168 °C(lit.)
Boiling point:: 342.1±37.0 °C(Predicted)
Density: 1.612±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 2.87±0.10(Predicted)
form: Powder
color: White to beige to tan
BRN: 383740
InChI: InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
InChIKey: RNRLTTNKVLFZJS-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=C(Cl)C=C1C(O)=O
CAS DataBase Reference: 41667-95-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-36-26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 340219
Product name: 5,6-Dichloropyridine-3-carboxylic acid
Purity: 96%
Packaging: 5g
Price: $26
Updated: 2023/06/20

TCI Chemical

Product number: D2401
Product name: 5,6-Dichloronicotinic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $56
Updated: 2024/03/01

TCI Chemical

Product number: D2401
Product name: 5,6-Dichloronicotinic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $191
Updated: 2024/03/01

Alfa Aesar

Product number: B25586
Product name: 5,6-Dichloronicotinic acid, 98+%
Packaging: 25g
Price: $209
Updated: 2021/12/16

Alfa Aesar

Product number: B25586
Product name: 5,6-Dichloronicotinic acid, 98+%
Packaging: 5g
Price: $62.7
Updated: 2021/12/16

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5,6-Dichloronicotinic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

5,6-Dichloronicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2,3-DICHLOROPYRIDINE-5-CARBONYL CHLORIDE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER

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5,6-Dichloronicotinic acid Suppliers

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View Lastest Price from 5,6-Dichloronicotinic acid manufacturers

Zison Pharmaceutical (Shandong) Co., Ltd.

Product: 5,6-Dichloronicotinic acid 41667-95-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥98% by HPLC
Supply Ability: 50kg/month
Release date: 2023-01-05

Hebei Weibang Biotechnology Co., Ltd

Product: 5,6-Dichloronicotinic acid 41667-95-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-26

Hebei Yanxi Chemical Co., Ltd.

Product: 5,6-Dichloronicotinic acid 41667-95-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-11-13

41667-95-2, 5,6-Dichloronicotinic acidRelated Search:

Thionyl chloride Sodium dichloroisocyanurate Dichlorodimethylsilane Isonicotinic acid 6-Chloronicotinic acid 2-Chloronicotinic acid N,N-Dimethylacetamide 2,6-Dichloroisonicotinic acid Quinclorac 2,6-Dichloro-5-fluoronicotinic acid 4-Chloronicotinic acid EPA Dichloroethane 2-chloro-5-cyanopyridine 2-Mercaptonicotinic acid 6-Aminonicotinic acid 2,6-DICHLORONICOTINIC ACID 98%,2 6-DICHLORONICOTINIC ACID TECH. 90%,2,6-DICHLORONICOTINIC ACID 2,5-DICHLORONICOTINIC ACID

5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID

5,6-DICHLORONICOTINIC ACID

5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID

TIMTEC-BB SBB003623

5,6-Dichloropyridine-3-carboxylicacid,96%

5,6-Dichloro

5,6-DICHLORONICOTINIC ACID 98+%

5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid

5,6-Dichloropyridine-3-carboxylic acid, 98+%

5,6-DICHLORONICOTINIC A

5,6-Dichloropyridine-3-carboxylic acid, 5-Carboxy-2,3-dichloropyridine

2,3-dichloropyridine-5-carboxylic acid

5,6-Dichloronicotinic acid 97%

5,6-DichloronicotinicAcid&gt

5,6-DichL

3-Pyridinecarboxylic acid, 5,6-dichloro-

Avatrombopag Impurity 10

5,6-Dichloronicotinic acid ISO 9001：2015 REACH

Avatroposide impurities16

(4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-3-yl)methanone

Avatrhopal Impurity 45

41667-95-2

1667-95-2

Pyridines

Heterocyclic Building Blocks

Halogenated Heterocycles

Building Blocks

Chloropyridines

Halopyridines

Heterocycle-Pyridine series

Chloropyridines

Halopyridines

Pyridine

Building Blocks

C5 to C6

C6 to C7

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridines

pharmacetical

Organic acids

Pyridines, Pyrimidines, Purines and Pteredines

Intermediate