Uses
ChemicalBook > CAS DataBase List > Ethyl 4,6-dichloronicotinate

Ethyl 4,6-dichloronicotinate

Uses
Product Name
Ethyl 4,6-dichloronicotinate
CAS No.
40296-46-6
Chemical Name
Ethyl 4,6-dichloronicotinate
Synonyms
ethyl 4,6-dichloropyridine-3-carboxylate;Novobiocin Impurity 5;Ethyl 4,6-dichloronitinate;Ethy14,6-dichloronicotinate;ETHYL 4,6-DICHLORONICOTINATE;Ethyl 4,6-dicholoronicotinate;Ethyl 4,6-Dichloronicotinate >Ethyl 4,6-dichloronicotinate ,97%;ethyl 4,6-dichloronicotinate (en);2,4-Dichloro-5-carbethoxypyridine
CBNumber
CB6102429
Molecular Formula
C8H7Cl2NO2
Formula Weight
220.05
MOL File
40296-46-6.mol
More
Less

Ethyl 4,6-dichloronicotinate Property

Melting point:
32-34°
Boiling point:
85°C/0.01mmHg(lit.)
Density 
1.367±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in methanol.
pka
-1.24±0.10(Predicted)
form 
Liquid
color 
Yellow
InChI
InChI=1S/C8H7Cl2NO2/c1-2-13-8(12)5-4-11-7(10)3-6(5)9/h3-4H,2H2,1H3
InChIKey
AAUBVINEXCCXOK-UHFFFAOYSA-N
SMILES
C1=NC(Cl)=CC(Cl)=C1C(OCC)=O
More
Less

Safety

Risk Statements 
36/37/38
Safety Statements 
26-36
HazardClass 
IRRITANT
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
E1068
Product name
Ethyl 4,6-Dichloronicotinate
Purity
>98.0%(GC)
Packaging
1g
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
E1068
Product name
Ethyl 4,6-Dichloronicotinate
Purity
>98.0%(GC)
Packaging
5g
Price
$54
Updated
2024/03/01
Alfa Aesar
Product number
H63092
Product name
Ethyl 4,6-dichloronicotinate, 95%
Packaging
1g
Price
$63
Updated
2023/06/20
Alfa Aesar
Product number
H63092
Product name
Ethyl 4,6-dichloronicotinate, 95%
Packaging
5g
Price
$242
Updated
2023/06/20
Alfa Aesar
Product number
H63092
Product name
Ethyl 4,6-dichloronicotinate, 95%
Packaging
250mg
Price
$18.7
Updated
2021/12/16
More
Less

Ethyl 4,6-dichloronicotinate Chemical Properties,Usage,Production

Uses

Ethyl 4,6-Dichloronicotinate acts as a reactant in the preparation of (acylamino)aminonaphthyridinones as novobiocin analogs and Hsp90 inhibitors, their antitumor activities in human breast cancer cell lines, and the effects on aptoptosis and cell cycle advancement of selected compounds.

Chemical Properties

White solid

Uses

Ethyl 4,6-dichloronicotinate is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals, and dyestuffs. It is also used as a fine chemical intermediate. Ethyl-4,6-dichloronicotinate could be used as a starting material to synthesize 6-chlorothieno[3,2-c]pyridine-2-carbohydrazide-hydrazone subsidiaries[1].

References

[1] N. Rao, K. Prasad, M. Rao. “Synthesis and Antibacterial Evaluation of Hydrazone Derivatives Bearing 6-Chlorothieno[3,2-c]pyridine Moiety.” Asian Journal of Chemistry 1 1 (2019).

Ethyl 4,6-dichloronicotinate Preparation Products And Raw materials

Raw materials

Diethyl 1,3-acetonedicarboxylate Ammonium hydroxide Ethanol Acetic anhydride Triethyl orthoformate Phosphorus oxychloride Hydrochloric acid Sodium hydroxide

Preparation Products

More
Less

Ethyl 4,6-dichloronicotinate Suppliers

Americas 1 Belgium 1 China 279 Europe 1 France 3 Germany 6 India 12 Japan 1 Switzerland 2 The Netherlands 2 Ukraine 2 United Kingdom 9 United States 40 Global 359
Wuxi InterpiPharm, Inc.
Tel
510-83782303 13771177691
Fax
0510- 8378-9906
Email
sales@itppharm.com
Country
China
ProdList
110
Advantage
62
Changzhou Qinuo Chemical Co., Ltd.Co., Ltd.
Tel
0519-0519-83812535
Email
sales@qinuochem.com
Country
China
ProdList
287
Advantage
60
Taizhou FRIEND Chemical Co., Ltd.
Tel
0523-86200082 15380713688
Fax
0523-86200991
Email
Austin@fredchem.cn
Country
China
ProdList
206
Advantage
55
Zhenjiang Carbochem Pharmatech Co.,LTD
Tel
0511-82018158 18136818960
Email
sales4@carbo-chem.com
Country
China
ProdList
292
Advantage
58
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
971
Advantage
62
Lanzhou Ulight Chemical Technology Co. Ltd
Tel
13919285024
Fax
13919285024
Email
863719335@qq.com
Country
China
ProdList
65
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2963
Advantage
65
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098-8020 13817598959
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
181
Advantage
55
Chiba Pharmaceutical Science and technology Co, Ltd.
Tel
0531-81313138 13066006660
Fax
QQ: 3366077777
Email
chibapharm@foxmail.com
Country
China
ProdList
4056
Advantage
55
Nanjing JinruiJiuAn Biotechnology Co., Ltd.
Tel
025-58196018 800028039
Fax
025-83453306
Email
sales@fartop.net
Country
China
ProdList
2229
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9459
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
Shanghai potentpharm CO.,Ltd
Tel
(86) 21 51969655
Fax
(86) 21 51969655， QQ：33109286， 263541193
Country
China
ProdList
487
Advantage
22
China Shenyang Tyschem CO. ,LTD
Tel
+86-024-83607930; 18640359690
Fax
024-83607930
Email
sales@honghuchem.com
Country
China
ProdList
126
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Chainpharm Bio-medical Technology Co., Ltd.
Tel
021-61727342 13611721451
Fax
021-61294107
Email
sales@chainpharm.com
Country
China
ProdList
957
Advantage
58
Shanghai Hong-chuang Pharma Tech Co., Ltd.
Tel
18151128828
Fax
-
Email
hc-sales@foxmail.com
Country
China
ProdList
2598
Advantage
55
Aloespharm Co., Ltd.
Tel
021-20960837
Fax
021-20960837
Email
market@aloespharm.com
Country
China
ProdList
1302
Advantage
55
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Taizhou Tongxin Bio-Tech Co., Ltd
Tel
0523-18601685-898 18652728585
Email
sales@allyrise.com
Country
China
ProdList
2769
Advantage
60
Beijin Yangguang Furui Chemical co.,Ltd.
Tel
010-57495520 13521095525
Email
zhw512@foxmail.com
Country
China
ProdList
488
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Hangzhou Trylead Chemical Technology Co.,LTD
Tel
0571-87086220 13516718938
Fax
0571-87012927
Email
zyf@trylead-chem.com
Country
China
ProdList
307
Advantage
64
Zhengzhou HongSheng Pharmaceutical Co., Ltd.
Tel
0371-13526885213 15637198702
Fax
0371-63709726
Email
xpkchem@163.com
Country
China
ProdList
3990
Advantage
58
Chemfun Medical Technology(Shanghai) Co., Ltd.
Tel
021-67220633 021-54824098
Fax
+86-21-54824069
Email
chemfun@chemfun.net
Country
China
ProdList
491
Advantage
58
Modachem Shanghai Co., Ltd
Tel
+86 (0)21 51320687 51371369 1744605818
Fax
+86 (0)21 51371369
Country
China
ProdList
1578
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10276
Advantage
55
Jinan LuoHe PharmaTech Co., Ltd.
Tel
0531-68658065 15726150375
Fax
0531-68658065
Email
jinanluohe@163.com
Country
China
ProdList
493
Advantage
58
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4767
Advantage
60
More
Less

View Lastest Price from Ethyl 4,6-dichloronicotinate manufacturers

Suzhou Nordica Biopharma CO.,LTD
Product
Ethyl 4,6-dichloronicotinate 40296-46-6
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
0.99
Supply Ability
1 ton
Release date
2024-11-15
hebei hongtan Biotechnology Co., Ltd
Product
Ethyl 4,6-dichloronicotinate 40296-46-6
Price
US $20.00/g
Min. Order
10g
Purity
98%
Supply Ability
2000kg
Release date
2024-03-26
Hebei Yanxi Chemical Co., Ltd.
Product
Ethyl 4,6-dichloronicotinate 40296-46-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-22

40296-46-6, Ethyl 4,6-dichloronicotinateRelated Search:

Ethyl acetoacetate 4,6-Dichloronicotinic acid 6-Chloronicotinic acid Ethyl pyruvate Ethyl acrylate Thionyl chloride Ethyl oleate Ethyl acetate Ethanol 2-Chloronicotinic acid Ethyl nicotinate 2,5-Dichloronicotinic acid 2,6-Dichloronicotinic acid Tris(trimethylsilyl)phosphate 5,6-Dichloronicotinic acid Ethyl formate Ethyl cyanoacetate Ethylparaben

  • 4,6-Dichloronicotinic acid ethyl ester ,97%
  • ethyl 4,6-dichloronicotinate (en)
  • Ethyl 4,6-dichloronicotinate ,97%
  • ethyl 4,6-dichloropyridine-3-carboxylate
  • 3-Pyridinecarboxylicacid,4,6-dichloro-,ethylester
  • 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER
  • 4,6-DICHLORONICOTINIC ACID ETHYL ESTER
  • ETHYL 4,6-DICHLORONICOTINATE
  • 2,4-Dichloro-5-carbethoxypyridine
  • 2,4-dichloropyridin-5-carboxylic acid,ethyl ester
  • Ethyl 4,6-dicholoronicotinate
  • Ethyl 4,6-dichloropyridine-3-carboxylate, 2,4-Dichloro-5-(ethoxycarbonyl)pyridine
  • Ethyl 4,6-Dichloronicotinate &gt
  • Ethyl 4,6-dichloronitinate
  • Novobiocin Impurity 5
  • Ethyl 4,6-dichloronicotinate ISO 9001：2015 REACH
  • Ethyl 4,6-dichloro-3-pyridinecarboxylate
  • Ethy14,6-dichloronicotinate
  • 40296-46-6
  • Pyridine series
  • Boronic Acid