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Atorvastatin lactone

Product Name
Atorvastatin lactone
CAS No.
125995-03-1
Chemical Name
Atorvastatin lactone
Synonyms
5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide;PD-130694;ATORVASTATIN LACTONE;Atorvastatin USP RC H;Atorvastatin calcium-6;Atorvastatin d-Lactone;Atorvastatin Impurity H;LACTONE IMPURITY(IMP-H);(RS) Atorvastatin Lactone;Atorvastatin EP IMpurity H
CBNumber
CB4313438
Molecular Formula
C33H33FN2O4
Formula Weight
540.62
MOL File
125995-03-1.mol
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Atorvastatin lactone Property

Melting point:
103-106°C
alpha 
D +26.05° (c = 1 in chloroform)
Boiling point:
674.8±55.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
13.39±0.40(Predicted)
form 
Solid
color 
White to Light Yellow
Merck 
14,864
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Safety

HS Code 
2933.99.7500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1044582
Product name
Atorvastatin Related Compound H
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
20MG
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
A3114
Product name
Atorvastatin Lactone
Purity
>95.0%(HPLC)
Packaging
25mg
Price
$122
Updated
2024/03/01
TCI Chemical
Product number
A3114
Product name
Atorvastatin Lactone
Purity
>95.0%(HPLC)
Packaging
100mg
Price
$362
Updated
2024/03/01
Cayman Chemical
Product number
20951
Product name
Atorvastatin lactone
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20951
Product name
Atorvastatin lactone
Purity
≥95%
Packaging
5mg
Price
$116
Updated
2024/03/01
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Atorvastatin lactone Chemical Properties,Usage,Production

Chemical Properties

Slightly Yellow Solid

Uses

Atorvastatin intermediate as inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation

Uses

Atorvastatin Lactone (Atorvastatin EP Impurity H) is an intermediate of Atorvastatin, a inhibitor of MAP kinase and/or HMG-CoA reductase for the treatment of inflammation.

Atorvastatin lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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Atorvastatin lactone Suppliers

Americas 1 Canada 3 China 149 Europe 1 India 21 Japan 1 United Kingdom 2 United States 17 Global 195
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from Atorvastatin lactone manufacturers

Guangzhou PI PI BIOTECH INC
Product
Atorvastatin Impurity H(EP) 125995-03-1
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-06-04
Guangzhou PI PI BIOTECH INC
Product
Atorvastatin Impurity E Intermediate
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-06-04
Hangzhou ICH Biofarm Co., Ltd
Product
5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide 125995-03-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500
Release date
2023-07-06

125995-03-1, Atorvastatin lactoneRelated Search:

Phenyl salicylate Diphenyl ether Polyvinylpyrrolidone Atorvastatin calcium Isopropyl alcohol N-Methyl-2-pyrrolidone Pyrrolidine PHENYL VALERATE ISOPROPYL LAURATE N-Vinyl-2-pyrrolidone TRIOXSALEN Atorvastatin tert-Butyl (4R,6R)-2-[[[6-(2-4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate Defluoro Atorvastatin Atorvastatin Impurity 40 PHENYL RESIN Phenylacetic acid 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt

  • 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide
  • Atorvastatin EPIMp H (USP RCH)
  • Atorvastatin EP IMpurity H
  • Atorvastatin Related Compound H (20 mg) (5-(4-Fluorophenyl)-1-{2-[(2R, 4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-2-isopropyl-N,4-diphenyl-1H-pyrrole-3-carboxamide)
  • Diepoxide Atorvastatin Lactone Diepoxide
  • Atorvastatin Calcium Impurity D
  • Atorvastatin Impurity H
  • (RS) Atorvastatin Lactone
  • ATORVASTATIN LACTONE
  • Atorvastatin lactone (EP impurity H)
  • (4R,6R)-6-[2-[2-(4-flfluorophenyl)-5-(1-methylethyl)-3- phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]ethyl]-4- hydroxytetrahydro-2H-pyran-2-one
  • Atorvastatin Impurity H(EP)
  • Atorvastatin USP RC H
  • Atorvastatin EP Impurity H (USP RC H)Ator. Lacton
  • Atorvastatin impurity 9/Atorvastatin EP Impurity H/Atorvastatin Lactone/5-(4-fluorophenyl)-2-(1-methyl-ethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro- hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
  • Atorvastatin calcium-6
  • 5-(4-fluorophenyl)-1-(2-((2R,4R)
  • Atorvastatin Calcium Hydrate impurity H
  • Atorvastatin EP Impurity H (Atorvastatin Lactone)
  • 5-(4-Fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide
  • Atorvastatin d-Lactone
  • (4R,6R)-6-{2-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]ethyl}-4-hydroxytetrahydro-2H-pyran-2-one
  • 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide
  • (3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-yl]-3,5-dihydroxyheptanoic acid 1,5-lactone
  • (4R,6R)-6-[2-[2-(4-Fluorophenyl)-5-
  • Atorvastatin Lactone (Atorvastatin EP Impurity H)
  • PD-130694
  • 1H-Pyrrole-3-carboxamide, 5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-
  • 1-[2-[[(2R)-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2α-yl]ethyl]-5-(4-fluorophenyl)-2-isopropyl-4,N-diphenyl-1H-pyrrole-3-carboxamide
  • Atorvastatin lactone ( imp H)
  • USP Atorvastatin Related Compound H
  • Atorvastatin EP Impurity H/ Atorvastatin Related Compound H (Atorvastatin Lactone)
  • Atorvastatin D5 LactoneQ: What is Atorvastatin D5 Lactone Q: What is the CAS Number of Atorvastatin D5 Lactone Q: What is the storage condition of Atorvastatin D5 Lactone Q: What are the applications of Atorvastatin D5 Lactone
  • Atorvastatin LactoneQ: What is Atorvastatin Lactone Q: What is the CAS Number of Atorvastatin Lactone Q: What is the storage condition of Atorvastatin Lactone Q: What are the applications of Atorvastatin Lactone
  • Atorvastatin Related Compound H (1044582)Q: What is Atorvastatin Related Compound H (1044582) Q: What is the CAS Number of Atorvastatin Related Compound H (1044582)
  • AtorvastatinEPImpurityH-d5
  • Atorvastatin USP Related Compound H
  • Atorvastatin Calcium Trihydrate EP Impurity H
  • LACTONE IMPURITY(IMP-H)
  • Atorvastatin Calcium Trihydrate Impurity H
  • Atorvastatin calcium impurity H
  • Atorvastatin EP Impurity H (Atorvastatin USP Related Compound H, Atorvastatin Lactone)
  • 125995-03-1
  • C33H33FN2O4
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals