PROFOXYDIM-LITHIUM
- Product Name
- PROFOXYDIM-LITHIUM
- CAS No.
- 139001-49-3
- Chemical Name
- PROFOXYDIM-LITHIUM
- Synonyms
- AIK;AURA;STK7;BTAK;STK6;ARK1;AIRK1;AURKA;STK15;TETRIS
- CBNumber
- CB4320465
- Molecular Formula
- C24H32ClNO4S
- Formula Weight
- 466.03
- MOL File
- 139001-49-3.mol
PROFOXYDIM-LITHIUM Property
- Melting point:
- <25 °C
- Boiling point:
- 597.2±60.0 °C(Predicted)
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- -70°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 4.25±0.25(Predicted)
- color
- White to Off-White
- Stability:
- Hygroscopic, Unstable in Solution
- EPA Substance Registry System
- Profoxydim (139001-49-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H351Suspected of causing cancer
- Precautionary statements
-
P201Obtain special instructions before use.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SRP5034
- Product name
- GRK2, active, GST tagged human
- Purity
- PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 10μG
- Price
- $520
- Updated
- 2024/03/01
- Product number
- CHM0290689
- Product name
- PROFOXYDIM-LITHIUM
- Purity
- 98.00%
- Packaging
- 1G
- Price
- $1238.16
- Updated
- 2021/12/16
PROFOXYDIM-LITHIUM Chemical Properties,Usage,Production
Uses
Profoxydim Lithium Salt is a salt of Profoxydim (139001-49-3) and an herbicide.
Definition
ChEBI: Profoxydim is a cyclic ketone that is 3-hydroxycyclohex-2-en-1-one substituted by a N-[2-(4-chlorophenoxy)propoxy]butanimidoyl group at position 2 and by a thian-3-yl group at position 5. It is a herbicide used for the control of grass weeds in rice. It has a role as a herbicide and an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. It is an oxime O-ether, a member of monochlorobenzenes, an aromatic ether, an enol, an organosulfur heterocyclic compound and a cyclic ketone.
General Description
G-protein-coupled receptor kinase 2 (GRK2), which is officially known as adrenergic, beta, receptor kinase 1 (ADRBK1), gene codes for a 689 amino acid protein, that is of 79.573kDa. This gene has 12 catalytic region subdomains. GRK2 is expressed in the vascular endothelium, arterial smooth muscle, myocardium, kidney and in the renal proximal tubule. It is mapped to human chromosome 11q13.
Biochem/physiol Actions
G-protein-coupled receptor kinase 2 (GRK2) or ADRBK1 is a ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G protein-coupled receptors. GRK2 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. RAF kinase inhibitor protein RKIP is a physiologic inhibitor of GRK2. After stimulation of G protein-coupled receptors, RKIP dissociates from its known target, RAF1 to associate with GRK2 and block its activity. G-protein-coupled receptor kinase 2 (GRK2) controls several intracellular mechanisms. It helps to maintain the structure and activities of the heart. Hence it participates in several cardiovascular diseases. GRK2 also modulates ion and fluid transport and eventually, blood pressure. It increases the synthesis of mitochondrial superoxide and reduces oxygen utilization and ATP synthesis. This protein serves as a major onco-modulator.
PROFOXYDIM-LITHIUM Preparation Products And Raw materials
Raw materials
Preparation Products
PROFOXYDIM-LITHIUM Suppliers
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- China
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View Lastest Price from PROFOXYDIM-LITHIUM manufacturers
- Product
- Profoxydim-lithium 139001-49-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2020-01-13
- Product
- PROFOXYDIM-LITHIUM 139001-49-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 10kg
- Release date
- 2018-12-18