ChemicalBook > CAS DataBase List > 1,3-Dimethyladamantane

1,3-Dimethyladamantane

Product Name
1,3-Dimethyladamantane
CAS No.
702-79-4
Chemical Name
1,3-Dimethyladamantane
Synonyms
Dimethyladamantane;1,3-DIMETHYL ADAMANTINE;MeMantine Related CoMpound A;Memantine USP RC A;1,3-Dimethyladamanta;1, 3-dimethylfungane;3-Dimethyl Adamantane;Adamantane Impurity A;Memantine intermediate;1,5-Dimethyladamantane
CBNumber
CB4335302
Molecular Formula
C12H20
Formula Weight
164.29
MOL File
702-79-4.mol
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1,3-Dimethyladamantane Property

Melting point:
-30 °C
Boiling point:
201.5 °C
Density 
0.886 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.478(lit.)
Flash point:
127 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
clear liquid
Specific Gravity
0.886
color 
Colorless to Almost colorless
Stability:
Stable. Incompatible with strong oxidizing agents. Flammable.
InChI
InChI=1S/C12H20/c1-11-4-9-3-10(5-11)7-12(2,6-9)8-11/h9-10H,3-8H2,1-2H3
InChIKey
CWNOIUTVJRWADX-UHFFFAOYSA-N
SMILES
C12(C)CC3CC(CC(C)(C3)C1)C2
CAS DataBase Reference
702-79-4(CAS DataBase Reference)
NIST Chemistry Reference
Adamantane, 1,3-dimethyl-(702-79-4)
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Safety

Hazard Codes 
F
Risk Statements 
10
Safety Statements 
16-60
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
HazardClass 
3
PackingGroup 
III
HS Code 
29021990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2449
Product name
Memantine Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$683.05
Updated
2025/07/31
Sigma-Aldrich
Product number
187836
Product name
1,3-Dimethyladamantane
Purity
≥99%
Packaging
5g
Price
$148.2
Updated
2025/07/31
Sigma-Aldrich
Product number
1380513
Product name
Memantine Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1300
Updated
2025/07/31
TCI Chemical
Product number
D1081
Product name
1,3-Dimethyladamantane
Purity
>99.0%(GC)
Packaging
5mL
Price
$54
Updated
2025/07/31
TCI Chemical
Product number
D1081
Product name
1,3-Dimethyladamantane
Purity
>99.0%(GC)
Packaging
25mL
Price
$159
Updated
2025/07/31
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1,3-Dimethyladamantane Chemical Properties,Usage,Production

Chemical Properties

clear colourless liquid

Uses

1,3-Dimethyladamantane is a dimethylated adamantane derivative. Memantine impurity A. Memantine Related Compound A (1,3-Dimethyladamantane).

Application

1,3-Dimethyladamantane was used in the synthesis of 1,3-dibromo-5,7-dimethyladamantane.

Definition

ChEBI: 1,3-dimethyladamantane is a polycyclic alkane and a member of adamantanes. It derives from a hydride of an adamantane.

General Description

1,3-Dimethyladamantane undergoes C-H insertion reaction with phenylchlorocarbene. It reacts with with molecular oxygen in the presence of N-hydroxyphthalimide combined with cobalt salts to yield 3,5-dimethyladamantan-1-ol and 5,7-dimethyladamantane-1,3-diol.

Synthesis

941-37-7

702-79-4

GENERAL METHODS: A thiocarbonate solution was prepared by dissolving 5 g (107 mg, 0.200 mmol) of 1-bromo-3,5-dimethyladamantane in CPME (0.5 mL). Subsequently, a solution of n-Bu3SnH (75.7 mg, 0.260 mmol) and AIBN (6.6 mg, 0.040 mmol) in CPME (1.5 mL) was slowly added dropwise by syringe pump to the above thiocarbonate solution, and the reaction lasted for 30 min at 90 °C. After completion of the reaction, the mixture was continued to be stirred at the same temperature for 30 min, followed by concentration. The residue was purified by 10% w/w K2CO3-silica gel fast column chromatography using gradient elution (hexane → hexane/EtOAc = 100/1 → 50/1 → 20/1) to afford 6 g of cis-consistently cyclized product (53.6 mg, 0.140 mmol, 70% yield) and a mixture of cis- and trans-consistently diastereoisomers (22.0 mg. 0.0572 mmol, 29% yield, cis-trans ratio of 2.8:1). For spectral analysis, these isomers were separated by repeated column chromatography.

References

[1] Tetrahedron, 2013, vol. 69, # 10, p. 2251 - 2259
[2] Organic Letters, 2008, vol. 10, # 4, p. 533 - 536
[3] Journal of Organic Chemistry, 1983, vol. 48, # 16, p. 2762 - 2765

1,3-Dimethyladamantane Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 1,3-Dimethyladamantane manufacturers

Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
Product
1,3-Dimethyladamantane 702-79-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-09-26
Wuhan JiyunZen Tech Co., Ltd.
Product
1,3-Dimethyladamantane 702-79-4
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-05-30
Hebei Fengjia New Material Co., Ltd
Product
1,3-Dimethyladamantane 702-79-4
Price
US $30.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
100 tons
Release date
2024-08-08

702-79-4, 1,3-DimethyladamantaneRelated Search:

Altrenogest Decane Amantadine Adamantane Dimethyl 1,3-adamantanedicarboxylate 1,3-Adamantanediacetic acid 1,3-adamantanedimethanol 4,4'-(1,3-ADAMANTANEDIYL)DIPHENOL 1,3-Adamantanedicarboxylic acid 1-Acetamido-3,5-dimethyladamantane 1-Hydroxy-3,5-dimethyladamantane 1-Amino-3,5-dimethyladamantane Memantine HCl 1-BROMO-3,5-DIMETHYLADAMANTANE 3,5-DIMETHYLADAMANTANE-1-CARBOXYLIC ACID 5-chloro-1,3-dimethyladamantane,1-CHLORO-3,5-DIMETHYLADAMANTANE 1,3-BIS(4-METHYLPHENYL)ADAMANTANE 3-(1,1,2,3,3,3-HEXAFLUOROPROPYL)ADAMANTANE-1-CARBOXYLIC ACID

  • Tricyclo[3.3.1.1(3,7)]decane, 1,3-dimethyl-
  • tricyclo[3.3.1.13,7]decane,1,3-dimethyl-
  • 1,3-DIMETHYLADAMANTANE, 99+%
  • Memantine intermediate
  • 1,3-Dimethyladamanta
  • 1,3-diMethyl alkyl fund just
  • 1,3-diMethyl adaMantanone
  • 1,3-Dimethyladamantane,98%
  • 1,5-Dimethyladamantane
  • Dimethyladamantane
  • MeMantine Related CoMpound A
  • Memantine USP RC A
  • Memantine USP Related Compound A
  • Memantine Hydrochloride Impurity A
  • 1,3-Dimethyladamantane 98%
  • 1,3-Dimethyltricyclo[3.3.1.13,7]decane
  • 1,3-DIMETHYLADAMANTANE
  • 1,3-DIMETHYL ADAMANTINE
  • Memantine Impurity 6(Memantine USP RC A)
  • (1r,3r,5s,7s)-1,3-dimethyladamantane
  • 1,3-Dimethyladamantane &gt
  • 3-Dimethyl Adamantane
  • Memantine Related Compund A (1,3-Dimethyladamantane)
  • MemantineRelatedCompoundA(1,3-Dimethyladamantane)
  • TIANFUCHEM--High purity 1,3-Dimethyladamantane factory price
  • Memantine Related Compound A (1,3-Dimethyladamantane) (1380513)
  • 1, 3-dimethylfungane
  • Memantine Related Compound A (1r,3r,5s,7s)-1,3-dimethyladamantane
  • 1,3-Dimethyladamantane in isooctane
  • Adamantane Impurity A
  • 1,3-Dimethyladamentane
  • 702-79-4
  • C12H20
  • Adamantanes
  • Cyclic
  • Organic Building Blocks
  • Alkanes
  • Building Blocks
  • Chemical intermediate for Memantine HCl
  • Adamantane derivatives
  • Adamantanes
  • Alkanes
  • Cyclic
  • Organic Building Blocks
  • bc0001
  • 702-79-4