beta-Sitosterol
- Product Name
- beta-Sitosterol
- CAS No.
- 83-46-5
- Chemical Name
- beta-Sitosterol
- Synonyms
- β-Sitosterol;SITOSTEROL;PHYTOSTEROL;B-SITOSTEROL;22,23-DIHYDROSTIGMASTEROL;Sterol;Stigmast-5-en-3beta-ol;sobatum;Quebrachol;nimbosterol
- CBNumber
- CB4345688
- Molecular Formula
- C29H50O
- Formula Weight
- 414.72
- MOL File
- 83-46-5.mol
beta-Sitosterol Property
- Melting point:
- 136-140 °C(lit.)
- alpha
- -28 º (c=2, CHCl3)
- Boiling point:
- 473.52°C (rough estimate)
- Density
- 0.9540 (rough estimate)
- refractive index
- 1.5000 (estimate)
- storage temp.
- 2-8°C
- solubility
- chloroform: 20 mg/mL, clear, colorless
- form
- White solid
- pka
- 15.03±0.70(Predicted)
- color
- White to Off-White
- optical activity
- -3725 (c 2, CHCl3)
- Water Solubility
- INSOLUBLE
- Merck
- 14,8556
- BRN
- 1916165
- InChIKey
- KZJWDPNRJALLNS-VJSFXXLFSA-N
- LogP
- 10.482 (est)
- CAS DataBase Reference
- 83-46-5(CAS DataBase Reference)
- NIST Chemistry Reference
- «beta»-Sitosterol(83-46-5)
- EPA Substance Registry System
- .beta.-Sitosterol (83-46-5)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-38-40-48/20/22-36/37/38-67-36/38-20-63
- Safety Statements
- 22-24/25-36-26-36/37
- RIDADR
- UN 1888 6.1/PG 3
- WGK Germany
- 3
- RTECS
- WJ2600000
- F
- 10
- HS Code
- 29061990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P273Avoid release to the environment.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- PHR2693
- Product name
- β-Sitosterol
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200?mg
- Packaging
- 200MG
- Price
- $292
- Updated
- 2024/03/01
- Product number
- PHL89283
- Product name
- β-Sitosterol
- Purity
- phyproof? Reference Substance
- Packaging
- 25MG
- Price
- $377
- Updated
- 2024/03/01
- Product number
- 567152
- Product name
- β-Sitosterol - CAS 83-46-5 - Calbiochem
- Purity
- Common plant steroid that possesses anticholesteremic properties.
- Packaging
- 5G
- Price
- $54.7
- Updated
- 2024/03/01
- Product number
- 567152
- Product name
- β-Sitosterol - CAS 83-46-5 - Calbiochem
- Purity
- Common plant steroid that possesses anticholesteremic properties.
- Packaging
- 25G
- Price
- $239
- Updated
- 2024/03/01
- Product number
- 47133
- Product name
- β-Sitosterol
- Purity
- certified reference material, 100?μg/mL in chloroform
- Packaging
- 1mL
- Price
- $45.5
- Updated
- 2024/03/01
beta-Sitosterol Chemical Properties,Usage,Production
Description
24α-ethyl Cholesterol is a naturally occurring plant sterol with antioxidant, anticancer, anti-
Chemical Properties
White powder
Uses
antiinflammatory, immunomodulator
Uses
A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma.This compound is a contaminant of emerging concern (CECs)
Definition
A steroid with long aliphatic side chains (8–10 carbons) and at least one hydroxyl group. They are lipidsoluble and often occur in membranes. Examples are cholesterol and ergosterol.
Definition
sterol: Any of a group of steroidbasedalcohols having a hydrocarbonside-chain of 8–10 carbon atoms.Sterols exist either as free sterols oras esters of fatty acids. Animal sterols(zoosterols) include cholesterol andlanosterol. The major plant sterol(phytosterol) is beta-sitosterol, whilefungal sterols (mycosterols) includeergosterol.
Definition
ChEBI: A phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3.
General Description
Sitosterol, also called as β-sitosterol, is synthesized through the mevalonate and deoxy xylulose pathways. Synthetically, it is synthesized from stigmasterol by Δ22–23 alkene group hydrogenation. Structurally sitosterol differ from cholesterol with ethyl (sitosterol) group in C24 position of side chain(65). Sitosterol is a lipid component of membranes. It corresponds to a molecular mass of 414.71 g/mol).
Biochem/physiol Actions
Sitosterol promotes the antioxidant levels and is used as an effective anti-inflammatory, antiapoptotic and anticancer agent in medicinal preparations. It acts as a neutralizing agent for the venom from viper and cobra. Sitosterol acts on protein kinase C (PKC) and in the sphingomyelin cycle to mediate tumor progression inhibition.
Purification Methods
Crystallise -sitosterol from EtOH, MeOH, Me2CO, Me2CO/EtOH or Me2CO/MeOH. It has also been purified by zone melting. The acetate crystallises from MeOH or EtOH as plates with m 127128o and [] D 20 -41o (c 2, CHCl3). The benzoate crystallises from EtOH as needles with m 146-147o and [] D 20 –13.8o (c 2, CHCl3). [Fujimoto & Jacobson J Org Chem 29 3377, 3381 1964, Shoppee J Chem Soc 10431948, Heilbron et al. J Chem Soc 344, 347 1941, Beilstein 6 III 2696.]
beta-Sitosterol Preparation Products And Raw materials
Raw materials
Preparation Products
beta-Sitosterol Suppliers
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- nfo@matrix-fine-chemicals.com
- Country
- Switzerland
- ProdList
- 6968
- Advantage
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- Tel
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- Fax
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- info@aschem.ch
- Country
- Switzerland
- ProdList
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- Tel
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- Country
- Switzerland
- ProdList
- 6896
- Advantage
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View Lastest Price from beta-Sitosterol manufacturers
- Product
- beta-Sitosterol 83-46-5
- Price
- US $100.00-75.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000Ton
- Release date
- 2024-08-09
- Product
- beta-Sitosterol 83-46-5
- Price
- US $20.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/Week
- Release date
- 2024-05-06
- Product
- beta-Sitosterol; Soybean extract 83-46-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- ≥ 98% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-23