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CHES

Product Name
CHES
CAS No.
103-47-9
Chemical Name
CHES
Synonyms
CHES;2-(N-CYCLOHEXYLAMINO)ETHANESULPHONIC ACID;N-CycL;CHES),CH;CHES, 98+%;CHES, ULTROL;CHES ULTRAPURE;CHES SIGMAULTRA;TIANFU-CHEM CHES;Cyclohexyltaurine
CBNumber
CB4356976
Molecular Formula
C8H17NO3S
Formula Weight
207.29
MOL File
103-47-9.mol
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CHES Property

Melting point:
≥300 °C
Density 
1.2045 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.5364 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: 0.5 M at 20 °C, clear, colorless
form 
Solid
color 
White
PH
3.0-5.0 (25℃, 0.5M in H2O)
pka
9.3(at 25℃)
PH Range
8.6 - 10.0
Odor
Odorless
Water Solubility 
Soluble
Sensitive 
Hygroscopic
λmax
λ: 260 nm Amax: 0.08
λ: 280 nm Amax: 0.05
Merck 
14,2055
BRN 
2967601
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
MKWKNSIESPFAQN-UHFFFAOYSA-N
LogP
-2.2 at 20℃
CAS DataBase Reference
103-47-9(CAS DataBase Reference)
EPA Substance Registry System
Ethanesulfonic acid, 2-(cyclohexylamino)- (103-47-9)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-20/22
Safety Statements 
26-28-24/25-16-60
WGK Germany 
3
3
TSCA 
Yes
HS Code 
29213099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
29311
Product name
CHES
Purity
BioUltra, ≥99.5% (T)
Packaging
10g
Price
$83.2
Updated
2024/03/01
Sigma-Aldrich
Product number
29311
Product name
CHES
Purity
BioUltra, ≥99.5% (T)
Packaging
50g
Price
$268
Updated
2024/03/01
Sigma-Aldrich
Product number
239779
Product name
CHES,ULTROLGrade-CAS103-47-9-Calbiochem
Purity
AzwitterionicbufferthatisusefulinthepH8.6-10.0range.HasapKaof9.15
Packaging
100g
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
RES1299C-B7
Product name
CHES
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture
Packaging
1pkg
Price
$250
Updated
2022/05/15
Sigma-Aldrich
Product number
3100-OP
Product name
OmniPur CHES - CAS 103-47-9 - Calbiochem
Packaging
100g
Price
$127
Updated
2022/05/15
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CHES Chemical Properties,Usage,Production

Chemical Properties

White/clear cryst. powder

Uses

CHES is zwitterionic buffer useful in pH range 8.6 to 10.0.CHES is widely utilized as a buffer which is used for investigations on pH-dependent processes in enzymology. It has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.

Uses

2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.

Definition

ChEBI: N-cyclohexyl-2-aminoethanesulfonic acid is an alkanesulfonic acid that is cyclohexanamine in which one of the amino hydrogens is substituted by a 2-sulfoethyl group. It is used as a buffer (pH range of 8.6-10.0) for studying pH-dependent processes in enzymology. It has a role as a Good's buffer substance. It is an alkanesulfonic acid and a secondary aliphatic amine.

Application

CHES belongs to the class of organic compounds known as cyclohexylamines. These are organic compounds containing a cyclohexylamine moiety, which consist of a cyclohexane ring attached to an amine group. It is often used as biological buffer. It can bind to hemagglutinin (HA) emulating with sialic acid (SA) and receptor binding site (RBS)-targeting broadly neutralizing antibodies.

General Description

CHES (2-(N-cyclohexylamino)ethanesulphonic acid) is regarded as Good′s buffers for its self-buffering and biocompatible feature. It is used in protein stabilization and does not interact with metals.

Flammability and Explosibility

Not classified

CHES Preparation Products And Raw materials

Raw materials

Preparation Products

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CHES Suppliers

Hunan Hengfei bio-pharmaceutical Co. , Ltd.
Tel
0746-6222194 13874779848
Fax
0746-6222194
Email
57182844@qq.com
Country
China
ProdList
86
Advantage
58
Hubei Chenxin Pharmaceutical Co., Ltd.
Tel
17362916295 17362916295
Fax
QQ:840947394
Email
w17362916295@163.com
Country
China
ProdList
3026
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Nanjing Search Biotech Co., Ltd
Tel
+86-025-81682922 +86-13515111588
Fax
025-85860962
Email
sales@searchbio.com.cn
Country
China
ProdList
135
Advantage
68
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View Lastest Price from CHES manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
N-Cyclohexyltaurine 103-47-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-09-07
Suzhou Genemill Biotechnology Co.,Ltd
Product
CHES 103-47-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.995
Supply Ability
1000tons
Release date
2023-09-14
Suzhou Genemill Biotechnology Co.,Ltd
Product
CHES-2-Cyclohexylaminoethanesulfonic Acid 103-47-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.995
Supply Ability
1000tons
Release date
2023-10-23

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