ChemicalBook > CAS DataBase List > CHES

CHES

Product Name
CHES
CAS No.
103-47-9
Chemical Name
CHES
Synonyms
CHES;2-(N-CYCLOHEXYLAMINO)ETHANESULPHONIC ACID;N-CycL;CHES),CH;CHES, 98+%;CHES, ULTROL;CHES ULTRAPURE;CHES SIGMAULTRA;TIANFU-CHEM CHES;Cyclohexyltaurine
CBNumber
CB4356976
Molecular Formula
C8H17NO3S
Formula Weight
207.29
MOL File
103-47-9.mol
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CHES Property

Melting point:
≥300 °C
Density 
1.2045 (rough estimate)
vapor pressure 
0Pa at 25℃
refractive index 
1.5364 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
H2O: 0.5 M at 20 °C, clear, colorless
form 
Solid
color 
White
PH
3.0-5.0 (25℃, 0.5M in H2O)
pka
9.3(at 25℃)
PH Range
8.6 - 10.0
Odor
Odorless
Water Solubility 
Soluble
Sensitive 
Hygroscopic
λmax
λ: 260 nm Amax: 0.08
λ: 280 nm Amax: 0.05
Merck 
14,2055
BRN 
2967601
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
MKWKNSIESPFAQN-UHFFFAOYSA-N
LogP
-2.2 at 20℃
CAS DataBase Reference
103-47-9(CAS DataBase Reference)
EPA Substance Registry System
Ethanesulfonic acid, 2-(cyclohexylamino)- (103-47-9)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36-20/22
Safety Statements 
26-28-24/25-16-60
WGK Germany 
3
3
TSCA 
Yes
HS Code 
29213099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
29311
Product name
CHES
Purity
BioUltra, ≥99.5% (T)
Packaging
10g
Price
$83.2
Updated
2024/03/01
Sigma-Aldrich
Product number
29311
Product name
CHES
Purity
BioUltra, ≥99.5% (T)
Packaging
50g
Price
$268
Updated
2024/03/01
Sigma-Aldrich
Product number
239779
Product name
CHES,ULTROLGrade-CAS103-47-9-Calbiochem
Purity
AzwitterionicbufferthatisusefulinthepH8.6-10.0range.HasapKaof9.15
Packaging
100g
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
RES1299C-B7
Product name
CHES
Purity
PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture
Packaging
1pkg
Price
$250
Updated
2022/05/15
Sigma-Aldrich
Product number
3100-OP
Product name
OmniPur CHES - CAS 103-47-9 - Calbiochem
Packaging
100g
Price
$127
Updated
2022/05/15
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CHES Chemical Properties,Usage,Production

Chemical Properties

White/clear cryst. powder

Uses

CHES is zwitterionic buffer useful in pH range 8.6 to 10.0.CHES is widely utilized as a buffer which is used for investigations on pH-dependent processes in enzymology. It has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.

Uses

2-(Cyclohexylamino)ethanesulfonic acid (CHES) has been used in the preparation of dimethyl trisulfide- polysorbate 80 (DMTS-PS80) formulation.

Definition

ChEBI: N-cyclohexyl-2-aminoethanesulfonic acid is an alkanesulfonic acid that is cyclohexanamine in which one of the amino hydrogens is substituted by a 2-sulfoethyl group. It is used as a buffer (pH range of 8.6-10.0) for studying pH-dependent processes in enzymology. It has a role as a Good's buffer substance. It is an alkanesulfonic acid and a secondary aliphatic amine.

Application

CHES belongs to the class of organic compounds known as cyclohexylamines. These are organic compounds containing a cyclohexylamine moiety, which consist of a cyclohexane ring attached to an amine group. It is often used as biological buffer. It can bind to hemagglutinin (HA) emulating with sialic acid (SA) and receptor binding site (RBS)-targeting broadly neutralizing antibodies.

General Description

CHES (2-(N-cyclohexylamino)ethanesulphonic acid) is regarded as Good′s buffers for its self-buffering and biocompatible feature. It is used in protein stabilization and does not interact with metals.

Flammability and Explosibility

Not classified

CHES Preparation Products And Raw materials

Raw materials

Preparation Products

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CHES Suppliers

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View Lastest Price from CHES manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
N-Cyclohexyltaurine 103-47-9
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
500kgs
Release date
2021-08-27
Hebei Yanxi Chemical Co., Ltd.
Product
N-Cyclohexyltaurine 103-47-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-13
Hebei Weibang Biotechnology Co., Ltd
Product
N-Cyclohexyltaurine 103-47-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25

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