2,6-Dimethylfluorobenzene

Product Name: 2,6-Dimethylfluorobenzene
CAS No.: 443-88-9
Chemical Name: 2,6-Dimethylfluorobenzene
Synonyms: 2-FLUORO-1,3-DIMETHYLBENZENE;2-FLUORO-M-XYLENE;Fluoroxylene3;FLUORO-M-XYLENE;2-Fluoro-m-xylene>2-Fluoro-m-xylene,98%;2,6-DIMETHYLFLUOROBENZENE;2,5-DIMETHYLFLUOROBENZENE;1-FLUORO-2,6-DIMETHYLBENZENE;1,3-dimethyl-2-fluorobenzene
CBNumber: CB4367264
Molecular Formula: C8H9F
Formula Weight: 124.16
MOL File: 443-88-9.mol

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2,6-Dimethylfluorobenzene Property

Boiling point:: 147-148 °C(lit.)
Density: 0.988 g/mL at 25 °C(lit.)
refractive index: n20/D 1.479(lit.)
Flash point:: 87 °F
storage temp.: 2-8°C
form: liquid
color: Clear, colourless
Specific Gravity: 0.988
Water Solubility: Not miscible or difficult to mix in water.
BRN: 1857413
InChI: InChI=1S/C8H9F/c1-6-4-3-5-7(2)8(6)9/h3-5H,1-2H3
InChIKey: JTAUTNBVFDTYTI-UHFFFAOYSA-N
SMILES: C1(C)=CC=CC(C)=C1F
CAS DataBase Reference: 443-88-9(CAS DataBase Reference)
NIST Chemistry Reference: 2,6-Dimethylfluorobenzene(443-88-9)

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Safety

Hazard Codes: F,Xn
Risk Statements: 10
Safety Statements: 16
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
Hazard Note: Flammable
HazardClass: 3
PackingGroup: III
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 452866
Product name: 2-Fluoro-1,3-dimethylbenzene
Purity: 97%
Packaging: 5ml
Price: $87.3
Updated: 2023/06/20

TCI Chemical

Product number: F0402
Product name: 2-Fluoro-m-xylene
Purity: >98.0%(GC)
Packaging: 5g
Price: $39
Updated: 2025/07/31

TCI Chemical

Product number: F0402
Product name: 2-Fluoro-m-xylene
Purity: >98.0%(GC)
Packaging: 25g
Price: $189
Updated: 2025/07/31

TRC

Product number: D465758
Product name: 2,6-Dimethylfluorobenzene
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: D465758
Product name: 2,6-Dimethylfluorobenzene
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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2,6-Dimethylfluorobenzene Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid

Uses

It is used in the spectroscopic observation of jet-cooled 2-fluoro-m-xylyl radical.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 21, p. 906, 1978 DOI: 10.1021/jm00207a013

Synthesis

87-62-7

443-88-9

Example 2: General procedure for synthesizing 2-fluoro-1,3-dimethylbenzene from 2,6-dimethylaniline The diazotization of 2,6-dimethylaniline (2.3 g, 0.02 mol) was carried out in an Et3N-3HF system under the same conditions as for 2,4,6-trimethylaniline in Example 1. Upon initial addition of sodium nitrite (2.0 g, 0.03 mol), the color of the reaction mixture gradually changed from yellow to red. A small amount of tar is generated during the reaction, which can be easily separated by solvent extraction. The post-treatment was consistent with the description of 2,4,6-trimethylaniline. The organic layer was extracted from the aqueous phase using diethyl ether (150 mL), and the organic extract was dried over magnesium sulfate and fractionated by solvent to give an orange colored oil. The oily substance was distilled at 141-143 °C and atmospheric pressure to give the colorless liquid 1-fluoro-2,6-dimethylbenzene (2.0 g, 86.3% yield). The distillation process was completed in 1 hour. The 1H NMR (CDCl3) spectrum of the product showed: δ 2.25 (2-CH3 and 6-CH3, d, J = 2.0 Hz, 6H); δ 6.91 (3-H and 5-H, dd, J = 8.3 Hz and J = 6.5 Hz, 2H); and δ 7.01 (4-H, t, J = 8.0 Hz, 1H).19F NMR (CDCl3) spectrum was found to be at δ 122.5 (1-F, ts, J = 6.5 Hz and J = 2.0 Hz) showed signals. Mass spectrometry analysis showed the molecular ion peak at m/z 124 and characteristic fragmentation peaks of 1-fluoro-2,6-dimethylbenzene were observed at m/z 109, 103, 96, 89, 83 and 77.

References

[1] Patent: US6179970, 2001, B2
[2] Journal of the American Chemical Society, 1992, vol. 114, # 7, p. 2482 - 2494
[3] Proceedings - Indian Academy of Sciences, Section A, 1959, vol. 50, p. 51,56, 58, 59
[4] Journal of Medicinal Chemistry, 1978, vol. 21, # 9, p. 906 - 913
[5] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1995, vol. 50, # 7, p. 1075 - 1078

2,6-Dimethylfluorobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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2,6-Dimethylfluorobenzene Suppliers

Americas 1 Belgium 1 China 157 Europe 3 France 1 Germany 4 India 4 Italy 1 Japan 1 Slovakia 1 Switzerland 2 United Kingdom 16 United States 25 Global 217

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View Lastest Price from 2,6-Dimethylfluorobenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2,6-Dimethylfluorobenzene 443-88-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Speranza Chemical Co., Ltd.

Product: 2,6-dimethylfluorobenzene 443-88-9
Price: US $20.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 200MT/ year
Release date: 2020-03-11

Henan Fengda Chemical Co., Ltd

Product: 2,6-Dimethylfluorobenzene 443-88-9
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

443-88-9, 2,6-DimethylfluorobenzeneRelated Search:

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2,6-DIMETHYLFLUOROBENZENE

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2,6-Dimethyl-1-fluorobenzene

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1,3-Dimethyl-2-fluorobenzene 98%

2-Fluoro-m-xylene&gt

2,6-Dimethylfluorobenzene ISO 9001：2015 REACH

443-88-9

443-89-9

433-88-9

CH32C6H3F

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